Pulse wave analysis measurements: important, underestimated and undervalued parameters in cardiovascular health problems
CONCLUSIONS: Following such investigations, CABPS appears as a robust predominant factor in problems of arterial stiffness. Pulse wave analysis and PWV are important parameters in the evaluation and monitoring of arterial hypertension and cardiovascular diseases. There is a hypothesis that CAAP could be an important and even decisive parameter in the diagnosis of ADHD. Further investigation needed.PMID:38028442 | PMC:PMC10653328 | DOI:10.3389/fcvm.2023.1266258 (Source: Atherosclerosis)
Source: Atherosclerosis - November 29, 2023 Category: Cardiology Authors: Philip Jan Claessens Ruth Peeters Louis Claessens Christophe Claessens Jan Claessens Philip Maria Claessens Source Type: research

Quantitative analysis of drugs of abuse and cognitive enhancers in influent wastewater by means of two chromatographic methods
Two methods for qualitative and quantitative analysis of selected drugs of abuse and a cognitive enhancer in wastewater samples were successfully developed and validated. A two-column setup was necessary for the analysis of all analytes included in this method. Evaluation of proof-of-concept samples enabled quantification of several analytes in wastewater grab samples, allowing the method to be used for monitoring trends in the consumption of the included analytes in wastewater. AbstractSewage-based epidemiology using influent wastewater is used to estimate the consumption trends of (illicit) drugs over a short or long per...
Source: Drug Testing and Analysis - November 28, 2023 Category: Drugs & Pharmacology Authors: Fabian Frankenfeld, Lea Wagmann, Cathy M. Jacobs, Markus R. Meyer Tags: RESEARCH ARTICLE Source Type: research

Efficacy of methylphenidate treatment in childhood myotonic dystrophy type 1 and comorbid attention deficit hyperactivity disorder: A case report using eye tracking assessment
We describe a case study of an eleven-year-old male patient with myotonic dystrophy type 1 and comorbid ADHD that was treated with methylphenidate in a twice daily regime (0.60  mg/kg/day). Positive effects on learning and cognition were reported by the parents and teachers. (Source: Brain and Development)
Source: Brain and Development - November 24, 2023 Category: Neurology Authors: Dirk J.J. Sweere, Jos G.M. Hendriksen, R. Jeroen Vermeulen, Sylvia Klinkenberg Tags: Case Report Source Type: research

Efficacy and Safety of Methylphenidate and Atomoxetine in Medication-Naive Children with Attention-Deficit Hyperactivity Disorder in a Real-World Setting
ConclusionsOverall, MPH was more effective and better tolerated than ATX. The incidence of AEs in children treated with MPH varied with age, and was higher in young children and lower in children over 10 years of age. (Source: Drugs in R&D)
Source: Drugs in R&D - November 20, 2023 Category: Drugs & Pharmacology Source Type: research

The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
Molecular Psychiatry, Published online: 13 November 2023; doi:10.1038/s41380-023-02314-6The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment (Source: Molecular Psychiatry)
Source: Molecular Psychiatry - November 13, 2023 Category: Psychiatry Authors: Susu Qu Xiangyu Zhou Zhicheng Wang Yi Wei Han Zhou Xinshuang Zhang Qingjie Zhu Yanmin Wang Quanjun Yang Likun Jiang Yuan Ma Yuan Gao Lei Kong Li Zhang Source Type: research

A new mechanistic insight into the association between environmental perfluorooctane sulfonic acid (PFOS) exposure and attention deficit and hyperactivity disorder (ADHD)-like behavior
This study enriches our understanding of the pathogenic mechanisms underlying ADHD development and emphasizes the importance of focusing on the health risks pertaining to environmental exposure.PMID:37952603 | DOI:10.1016/j.neuro.2023.11.004 (Source: Neurotoxicology)
Source: Neurotoxicology - November 12, 2023 Category: Neurology Authors: Miao Zhang Xueyan Gu Liu Wu Nannan Wan Yu Liu Zaijun Xin Tianbing Chen Shuai Liu Mingqi Li Mi Deng Qiyu Wang Source Type: research

A new mechanistic insight into the association between environmental perfluorooctane sulfonic acid (PFOS) exposure and attention deficit and hyperactivity disorder (ADHD)-like behavior
This study enriches our understanding of the pathogenic mechanisms underlying ADHD development and emphasizes the importance of focusing on the health risks pertaining to environmental exposure.PMID:37952603 | DOI:10.1016/j.neuro.2023.11.004 (Source: Neurotoxicology)
Source: Neurotoxicology - November 12, 2023 Category: Neurology Authors: Miao Zhang Xueyan Gu Liu Wu Nannan Wan Yu Liu Zaijun Xin Tianbing Chen Shuai Liu Mingqi Li Mi Deng Qiyu Wang Source Type: research

A new mechanistic insight into the association between environmental perfluorooctane sulfonic acid (PFOS) exposure and attention deficit and hyperactivity disorder (ADHD)-like behavior
This study enriches our understanding of the pathogenic mechanisms underlying ADHD development and emphasizes the importance of focusing on the health risks pertaining to environmental exposure.PMID:37952603 | DOI:10.1016/j.neuro.2023.11.004 (Source: Neurotoxicology)
Source: Neurotoxicology - November 12, 2023 Category: Neurology Authors: Miao Zhang Xueyan Gu Liu Wu Nannan Wan Yu Liu Zaijun Xin Tianbing Chen Shuai Liu Mingqi Li Mi Deng Qiyu Wang Source Type: research