Restrictive physiology masked by cardiac tamponade: A rare cooccurrence in a child with lymphoblastic T-cell lymphoma
We describe a 14-year-old boy with advanced T-cell lymphoma presenting with cardiac tamponade. Repeat echocardiography after pericardiocentesis revealed mediastinal mass infiltrating cardiac chambers and great vessels along with features of RCM secondary to tumor infiltration. (Source: Annals of Pediatric Cardiology)
Source: Annals of Pediatric Cardiology - June 14, 2022 Category: Cardiology Authors: Atit A Gawalkar Soumitra Ghosh Dinakar Bootla Pruthvi C Revaiah Charanpreet Singh Parminder Singh Otaal Source Type: research

Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction
Circ Res. 2022 Jun 10;130(12):1888-1905. doi: 10.1161/CIRCRESAHA.122.320246. Epub 2022 Jun 9.ABSTRACTHeart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic dysfunction, or both. Several factors chronically lead to HF, including cardiac volume and pressure overload that may result from hypertension, valvular lesions, acute, or chronic ischemic injuries. Major forms of HF include hypertrophic, dilated, and restrictive cardiomyopathy. The s...
Source: Circulation Research - June 9, 2022 Category: Cardiology Authors: Patrick M Pilz Jennifer E Ward Wei-Ting Chang Attila Kiss Edward Bateh Alokkumar Jha Sudeshna Fisch Bruno K Podesser Ronglih Liao Source Type: research

Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction
Circ Res. 2022 Jun 10;130(12):1888-1905. doi: 10.1161/CIRCRESAHA.122.320246. Epub 2022 Jun 9.ABSTRACTHeart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic dysfunction, or both. Several factors chronically lead to HF, including cardiac volume and pressure overload that may result from hypertension, valvular lesions, acute, or chronic ischemic injuries. Major forms of HF include hypertrophic, dilated, and restrictive cardiomyopathy. The s...
Source: Circulation Research - June 9, 2022 Category: Cardiology Authors: Patrick M Pilz Jennifer E Ward Wei-Ting Chang Attila Kiss Edward Bateh Alokkumar Jha Sudeshna Fisch Bruno K Podesser Ronglih Liao Source Type: research

Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction
Circ Res. 2022 Jun 10;130(12):1888-1905. doi: 10.1161/CIRCRESAHA.122.320246. Epub 2022 Jun 9.ABSTRACTHeart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic dysfunction, or both. Several factors chronically lead to HF, including cardiac volume and pressure overload that may result from hypertension, valvular lesions, acute, or chronic ischemic injuries. Major forms of HF include hypertrophic, dilated, and restrictive cardiomyopathy. The s...
Source: Circulation Research - June 9, 2022 Category: Cardiology Authors: Patrick M Pilz Jennifer E Ward Wei-Ting Chang Attila Kiss Edward Bateh Alokkumar Jha Sudeshna Fisch Bruno K Podesser Ronglih Liao Source Type: research

Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction
Circ Res. 2022 Jun 10;130(12):1888-1905. doi: 10.1161/CIRCRESAHA.122.320246. Epub 2022 Jun 9.ABSTRACTHeart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic dysfunction, or both. Several factors chronically lead to HF, including cardiac volume and pressure overload that may result from hypertension, valvular lesions, acute, or chronic ischemic injuries. Major forms of HF include hypertrophic, dilated, and restrictive cardiomyopathy. The s...
Source: Circulation Research - June 9, 2022 Category: Cardiology Authors: Patrick M Pilz Jennifer E Ward Wei-Ting Chang Attila Kiss Edward Bateh Alokkumar Jha Sudeshna Fisch Bruno K Podesser Ronglih Liao Source Type: research

Large and Small Animal Models of Heart Failure With Reduced Ejection Fraction
Circ Res. 2022 Jun 10;130(12):1888-1905. doi: 10.1161/CIRCRESAHA.122.320246. Epub 2022 Jun 9.ABSTRACTHeart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic dysfunction, or both. Several factors chronically lead to HF, including cardiac volume and pressure overload that may result from hypertension, valvular lesions, acute, or chronic ischemic injuries. Major forms of HF include hypertrophic, dilated, and restrictive cardiomyopathy. The s...
Source: Circulation Research - June 9, 2022 Category: Cardiology Authors: Patrick M Pilz Jennifer E Ward Wei-Ting Chang Attila Kiss Edward Bateh Alokkumar Jha Sudeshna Fisch Bruno K Podesser Ronglih Liao Source Type: research

Cardiac amyloidosis in Latin America: Gaps and opportunities to increase awareness of the disease. Findings from the AMILO-LATAM research group
ConclusionsThe surveys demonstrated the need for educational programs and other measures to increase clinical awareness and early detection of CA, so patients receive timely treatment and management of the disease. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - May 31, 2022 Category: Nuclear Medicine Source Type: research

Clinical genetic testing in four highly suspected pediatric restrictive cardiomyopathy cases
Restrictive cardiomyopathy (RCM) presents a high risk for sudden cardiac death in pediatric patients. Constrictive pericarditis (CP) exhibits a similar clinical presentation to RCM and requires differential di... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - May 25, 2022 Category: Cardiology Authors: Min Zheng, Hong Huang, Xu Zhu, Harvey Ho, Liling Li and Xiaojuan Ji Tags: Research Source Type: research

Endomyocardial fibrosis in a non ‐tropical patient who presented with chest pain mimicking ACS and left ventricular thrombus, case report
This report aims to increase the attention and awareness of this disease. We present a case of a 53-year-old man referred to the emergency department for sudden chest pain, left-sided and non-radiating lasted for several minutes, awoke him from sleep with no associated symptoms. He is known to have Diabetes type-2 and hypertension on oral therapy. Cardiac markers were within the normal limit. The patient was discharged home with an appointment at the cardiology outpatient clinic. Echocardiography was done and revealed mildly reduced left ventricular (LV) systolic function, Ejection Fraction of 46%, asymmetric LV hypertroph...
Source: Clinical Case Reports - May 23, 2022 Category: General Medicine Authors: Ahmad S. Matarneh, Yousef M. Ali Hailan, Sabir Abdul Karim, Maryam  A. Al Kuwari, Wafer A. Dabdoob Tags: CASE REPORT Source Type: research

Overview of Restrictive Cardiomyopathies
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):4-16. doi: 10.14797/mdcvj.1078. eCollection 2022.ABSTRACTRestrictive cardiomyopathy (RCM) includes a heterogeneous group of diseases that cause increased myocardial stiffness, leading to impaired ventricular relaxation and severe diastolic dysfunction. Given that it is the least common type of cardiomyopathy, it can be a diagnostic challenge due to its varied pathogenesis, clinical presentation, and diagnostic evaluation. In this review, we provide an overview of different etiologies of RCM and examine the diagnostic and treatment approaches for various types.PMID:35414858 ...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Smitha Narayana Gowda Hyeon-Ju Ali Imad Hussain Source Type: research

It Takes a Village: Multimodality Imaging of Cardiac Amyloidosis
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):47-58. doi: 10.14797/mdcvj.1072. eCollection 2022.ABSTRACTCardiac amyloidosis (CA) is the buildup and infiltration of amyloid plaque in cardiac muscle. An underdiagnosed form of restrictive cardiomyopathy, CA can rapidly progress into heart failure. CA is evaluated using a multimodality approach that includes echocardiography, cardiac magnetic imaging, and nuclear imaging. Echocardiography remains an essential first-line modality that raises suspicion for CA and establishes functional baselines. Cardiac magnetic imaging provides additional incremental value via high-resolut...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Jean Michel Saad Ahmed Ibrahim Ahmed Dixitha Anugula Yushui Han Moath Said Alfawara Mouaz H Al-Mallah Source Type: research

Cardiac Amyloidosis Treatment
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):59-72. doi: 10.14797/mdcvj.1050. eCollection 2022.ABSTRACTCardiac amyloidosis (CA) is a restrictive cardiomyopathy with a traditionally poor prognosis. Until recently, CA treatment options were limited and consisted predominantly of managing symptoms and disease-related complications. However, the last decade has seen significant advances in disease-modifying therapies, increased awareness of CA, and improved diagnostic methods resulting in earlier diagnoses. In this review, we provide an overview of current and experimental treatments for the predominant types of CA: trans...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Lily K Stern Jignesh Patel Source Type: research

Overview of Restrictive Cardiomyopathies
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):4-16. doi: 10.14797/mdcvj.1078. eCollection 2022.ABSTRACTRestrictive cardiomyopathy (RCM) includes a heterogeneous group of diseases that cause increased myocardial stiffness, leading to impaired ventricular relaxation and severe diastolic dysfunction. Given that it is the least common type of cardiomyopathy, it can be a diagnostic challenge due to its varied pathogenesis, clinical presentation, and diagnostic evaluation. In this review, we provide an overview of different etiologies of RCM and examine the diagnostic and treatment approaches for various types.PMID:35414858 ...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Smitha Narayana Gowda Hyeon-Ju Ali Imad Hussain Source Type: research

It Takes a Village: Multimodality Imaging of Cardiac Amyloidosis
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):47-58. doi: 10.14797/mdcvj.1072. eCollection 2022.ABSTRACTCardiac amyloidosis (CA) is the buildup and infiltration of amyloid plaque in cardiac muscle. An underdiagnosed form of restrictive cardiomyopathy, CA can rapidly progress into heart failure. CA is evaluated using a multimodality approach that includes echocardiography, cardiac magnetic imaging, and nuclear imaging. Echocardiography remains an essential first-line modality that raises suspicion for CA and establishes functional baselines. Cardiac magnetic imaging provides additional incremental value via high-resolut...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Jean Michel Saad Ahmed Ibrahim Ahmed Dixitha Anugula Yushui Han Moath Said Alfawara Mouaz H Al-Mallah Source Type: research

Cardiac Amyloidosis Treatment
Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):59-72. doi: 10.14797/mdcvj.1050. eCollection 2022.ABSTRACTCardiac amyloidosis (CA) is a restrictive cardiomyopathy with a traditionally poor prognosis. Until recently, CA treatment options were limited and consisted predominantly of managing symptoms and disease-related complications. However, the last decade has seen significant advances in disease-modifying therapies, increased awareness of CA, and improved diagnostic methods resulting in earlier diagnoses. In this review, we provide an overview of current and experimental treatments for the predominant types of CA: trans...
Source: Methodist DeBakey Cardiovascular Journal - April 13, 2022 Category: Cardiology Authors: Lily K Stern Jignesh Patel Source Type: research