Restrictive Cardiomyopathy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical features, etiology and survival in patients with restrictive cardiomyopathy: A single center experience
CONCLUSIONS: Genetic testing should be considered in every patient with RCM where light-chain amyloidosis has been excluded. Survival remains poor regardless of etiology. Increased concentrations of GDF15, hs-TNT, NT-proBNP and pericardial effusion are associated with worse prognosis. Further studies are warranted.PMID:37937352 | DOI:10.33963/v.kp.97879 (Source: Kardiologia Polska)
Source: Kardiologia Polska - November 8, 2023 Category: Cardiology Authors: Justyna A Szczygie ł Piotr Micha łek Gra żyna Truszkowska Joann Drozd-Soko łowska Aleksandra Wr óbel Maria Franaszczyk Monika Gawor-Prokopczyk Łukasz Mazurkiewicz Mateusz Ziarkiewicz Anna Waszczuk-Gajda Marta Legatowicz-Koprowska Ewa Walczak Piotr S Source Type: research

Clinical features, etiology and survival in patients with restrictive cardiomyopathy: A single center experience
CONCLUSIONS: Genetic testing should be considered in every patient with RCM where light-chain amyloidosis has been excluded. Survival remains poor regardless of etiology. Increased concentrations of GDF15, hs-TNT, NT-proBNP and pericardial effusion are associated with worse prognosis. Further studies are warranted.PMID:37937352 | DOI:10.33963/v.kp.97879 (Source: Polish Heart Journal)
Source: Polish Heart Journal - November 8, 2023 Category: Cardiology Authors: Justyna A Szczygie ł Piotr Micha łek Gra żyna Truszkowska Joann Drozd-Soko łowska Aleksandra Wr óbel Maria Franaszczyk Monika Gawor-Prokopczyk Łukasz Mazurkiewicz Mateusz Ziarkiewicz Anna Waszczuk-Gajda Marta Legatowicz-Koprowska Ewa Walczak Piotr S Source Type: research

VP163 Filaminopathy presenting as myofibrillar myopathy with nemaline bodies and ring fibers
The FLNC (filamin C) gene has been associated with autosomal dominant distal myopathy, autosomal dominant and autosomal recessive myofibrillar myopathy, autosomal dominant hypertrophic cardiomyopathy, and autosomal recessive restrictive cardiomyopathy, according to the 2023 version of the gene table of neuromuscular disorders. Myofibrillar myopathies are morphologically characterized by immunohistochemical ectopic expression of proteins, myofibrillar dissolution and disintegration of the Z-disk and abnormal accumulation of degradation products on electron microscopy. (Source: Neuromuscular Disorders)
Source: Neuromuscular Disorders - October 1, 2023 Category: Neurology Authors: A. Cotta, A da Cunha Junior, E. Carvalho, E. da Silveira, C. Costa e Silva, R. da Silva Neto, A. Cauhi, J. Valicek, A. Vargas Source Type: research

Thyroid hormone induces restrictive cardiomyopathy in β1-adrenoceptor knockout mice
Can J Physiol Pharmacol. 2023 Sep 25. doi: 10.1139/cjpp-2023-0153. Online ahead of print.ABSTRACTThe purpose of this study was to characterize the role of β1-AR signaling and its cross-talk between cardiac renin-angiotensin system and thyroid-hormone-induced cardiac hypertrophy. T3 was administered at 0.5 mg·kg-1·day-1 for 10 days in β1-KOT3 and WTT3 groups, while control groups received vehicle alone. Echocardiography and myocardial histology was performed; cardiac and serum ANGI/ANGII and ANP and cardiac levels of p-PKA, p-ERK1/2, p-p38-MAPK, p-AKT, p-4EBP1, and ACE were measured. WTT3 showed decreased IVSTd and incr...
Source: Canadian Journal of Physiology and Pharmacology - September 25, 2023 Category: Drugs & Pharmacology Authors: Anderson L B da Silveira Fernando A C Seara Danilo Lustrino Andr é S Mecawi Jos é Antunes-Rodrigues Ísis C Kettelhut Patr ícia Chakur-Brum Luis C Reis Emerson L Olivares Source Type: research