There's Relief In Sight For People With Perpetually Dry Eyes
By Janice Neumann (Reuters Health) - Tiny plugs inserted into the tear duct may safely curb the annoying and damaging effects of dry eyes, according to a new analysis of previous research. "Plugs are generally well tolerated," said Dr. Marcus Marcet, an ophthalmologist at the University of Hong Kong and the study's first author. "Overall the extent of relief depends on both the type of dry eye and the type of plug." Patients with dry eyes who might benefit from plugs are those who have already tried eye drops and gels but still have itchy, red, painful eyes, blurred vision and the sensation of a foreign body in the eye, ...
Source: Science - The Huffington Post - June 23, 2015 Category: Science Source Type: news

Consider combining therapies for atopic dermatitis
Cyclosporine and oral antihistamine therapy showed inconsistent effects on clinical and laboratory markers of atopic dermatitis in older children and adults, based on data from a study of 48 patients. A total of 25 patients aged 16-42 years received oral cyclosporine and 23 patients aged 15-32...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 9, 2015 Category: Dermatology Tags: IMN News IMN Dermatology FPN News FPN Dermatology SAN Clinical News SAN News SAN Atopic Dermatitis Source Type: news

3-D printed, mechanically robust carrier used to deliver immunosuppressive drug, and cells
(Cell Transplantation Center of Excellence for Aging and Brain Repair) After a 3-D printer was used to create a micro but mechanically robust drug and cell carrier for local and sustained delivery of the immunosuppressive drug cyclosporine, researchers demonstrated in tests with animal models that the carrier, a combination of microspheres and hydrogel, maintained robust shape and integrity and delivered a local, sustained release of CsA in an amount that prevented acceleration of cytokines and overcame the need for additional drugs to treat immune rejection. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 23, 2015 Category: Global & Universal Source Type: news

The Hearts Of Mary Shelley
"Perhaps a corpse would be reanimated... perhaps the components parts of a creature might be manufactured, brought together and endued with vital warmth." -Mary Shelley On Valentine's Day, we consider the heart. The heart is biological; it is the organ on which our life most depends. The heart is emotional, full of love and sorrow. The heart is wandering. No one knew our central muscle's multiple meanings better than Mary Shelley. Mary Shelley was a writer's writer, depressive, miserable, and brilliant. So too the friends she gathered with, at the age of 18, in the spring of 1816 at two adjacent houses on Lake Geneva...
Source: Science - The Huffington Post - February 11, 2015 Category: Science Source Type: news

Celgene’s Otezla® (apremilast) receives European marketing authorisation
Celgene UK announced that the European Commission has licenced Otezla®, the company’s oral selective inhibitor of phosphodiesterase 4 (PDE4), in two therapeutic indications: (2) For the treatment of moderate-to-severe chronic plaque psoriasis in adult patients who failed to respond to, or who have a contraindication to, or are intolerant to other systemic therapy including cyclosporine, methotrexate or psoralen and ultraviolet-A light (PUVA). Alone or in combination with disease-modifying antirheumatic drugs (DMARDs), for the treatment of active psoriatic arthritis in adult patients who have had an inadequate r...
Source: Pharmacy Europe - January 16, 2015 Category: Drugs & Pharmacology Authors: Annabel De Coster Tags: *** Editor's Pick Clinical trials Practical therapeutics Industry News Legislation & regulation Dermatology Rheumatology Patient care chronic plaque psoriasis DMARD Latest News PDE4 inhibitor psoriatic arthritis PUVA Source Type: news

Dollars for Dudes: Almost no women among medical industry's top-paid speakers, consultants
The causes are not clear, but men account for more than 90 percent of the 300 doctors who received the most money from drug and medical device companies, according to new federal data. Alison Tendler, an ophthalmologist who works in Sioux Falls, S.D., is among the few women on a list of the doctors paid the most money by drug companies last year. That's primarily because she serves as the TV advertising spokeswoman for the eye drug Restasis. Centers for Medicare and Medicaid Services (CMS), ProPublicaNews Well, Medicareread more (Source: Mass Device)
Source: Mass Device - October 8, 2014 Category: Medical Equipment Authors: MassDevice Source Type: news

How Does Pediatric Psoriasis Present?
Discussion Psoriasis is an inflammatory skin disease that is chronic and relapsing with periods of remission. It occurs in genetically susceptible persons and is felt to be triggered by environmental factors including infection (especially Group A, β-hemolytic streptococcus), emotional and physical stress, and skin irritation including friction, rubbing, pressure and scratching. It is common in patients with certain HLA types including HLA-Cw*0602, HLA-Cw6, IL-15 plus others. It occurs in about 1% of the general population with two age-onset peaks: 16-22 years and ~60 years, but can occur at any age. Some studies show...
Source: PediatricEducation.org - April 14, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Roche launches new tests for monitoring transplant patients on immunosuppressive therapy
Roche today announced the global launch (except US) of two new highly sensitive therapeutic drug monitoring tests for the immunosuppressant medicines tacrolimus and cyclosporine. The new Elecsys Tacrolimus and Cyclosporine tests provide healthcare professionals with more accurate and reliable results. They are made for use on Roche’s cobas modular analysers, thus also supporting enhanced workflow and efficiency in medical laboratories. (Source: Roche Media News)
Source: Roche Media News - July 19, 2013 Category: Pharmaceuticals Source Type: news

Roche launches new tests for monitoring transplant patients on immunosuppressive therapy
Roche today announced the global launch (except US) of two new highly sensitive therapeutic drug monitoring tests for the immunosuppressant medicines tacrolimus and cyclosporine. The new Elecsys Tacrolimus and Cyclosporine tests provide healthcare professionals with more accurate and reliable results. They are made for use on Roche’s cobas modular analysers, thus also supporting enhanced workflow and efficiency in medical laboratories. (Source: Roche Investor Update)
Source: Roche Investor Update - July 19, 2013 Category: Pharmaceuticals Source Type: news

Everolimus vs Mycophenolate Mofetil in Heart TransplantationEverolimus vs Mycophenolate Mofetil in Heart Transplantation
In an open-label, 24-month trial, 721 de novo heart transplant recipients were randomized to everolimus 1.5 mg or 3.0 mg with reduced-dose cyclosporine, or mycophenolate mofetil 3 g/day with standard-dose cyclosporine. American Journal of Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2013 Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news

Cyclosporine May Be an Option in Allergic ConjunctivitisCyclosporine May Be an Option in Allergic Conjunctivitis
Topical cyclosporine may spare patients the adverse effects associated with corticosteroids, investigators say. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 9, 2013 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Infliximab Better Than Cyclosporine in Refractory ColitisInfliximab Better Than Cyclosporine in Refractory Colitis
Infliximab appears to be better than cyclosporine as salvage therapy for steroid-refractory acute severe ulcerative colitis (UC), researchers from Australia report. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New Automated Immunosuppressive Drug Assays Improve Therapeutic Drug Monitoring for Transplant Patients
For the first time, certain immunosuppressive drug (ISD) assays can now be performed automatically on cobas® modular platforms, allowing laboratories to consolidate testing for a wide range of transplant testing/monitoring assays onto a single platform. The new Roche automated assays for tacrolimus and cyclosporine will enhance therapeutic drug monitoring (TDM) of transplant recipients by providing the consistency and accuracy of an automated assay, while enhancing workflows, auditing and reporting capabilities in the laboratory. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - July 2, 2013 Category: Pharmaceuticals Source Type: news

600th Heart Attack Patient Recruited Into Phase III CicloMulsion® CIRCUS Trial
NeuroVive, a leading mitochondrial medicine company, announces that the 600th patient has been recruited to a pivotal Phase III European, multi-center trial (CIRCUS trial) assessing CicloMulsion® (a special formulation of cyclosporine for acute cardiac injuries) for the treatment of heart reperfusion injury following stenting in patients with myocardial infarction... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 27, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news

Abuse of Opana ER (oxymorphone) associated with thrombotic thrombocytopenic purpura
3.5 out of 5 stars Thrombotic Thrombocytopenic Purpura (TTP)-Like Illness Associated with Intravenous Opana ER Abuse — Tennessee, 2012. MMWR 2013 Jan 11;62:1-4. Full Text This paper describes a 2012  CDC investigation into a cluster of 15 cases of thrombotic thrombocytopenic purpura (TTP)-like illness in the state of Tennessee. TTP-like illness was defined as microangiopathic hemolytic anemia (hemolytic anemia anemia based on haptoglobin and lactate dehydrogenase with schistocytes and an admission platelet count < 50,000/μL. Typical TTP-like signs and symptoms included nausea (11 patients), abdominal pain (11), f...
Source: The Poison Review - January 15, 2013 Category: Toxicology Authors: Leon Tags: Medical opana oxymorphone thrombotic thrombocytopenic purpura ttp Source Type: news