WCD: Methotrexate found safer but less effective than cyclosporine in atopic dermatitis

VANCOUVER, B.C. – In the first head-to-head trial in atopic dermatitis, cyclosporine was about five times more effective in terms of SCORAD 50 but was associated with more adverse events, Dr. Catherine Goujon-Henry reported at the World Congress of Dermatology. Based on the findings,...googletag.display('div-gpt-ad-cta');
Source: Skin and Allergy News - Category: Dermatology Tags: SAN Conference News IMN Conferences SAN Atopic Dermatitis SAN Clinical News SAN News IMN News IMN Dermatology Source Type: news

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Conclusions: Keeping a dog at home before and during pregnancy decreased the risk of food allergy in 1-year-old children. This effect was eliminated in case of having a cat, hamster, guinea pig, or rabbit. PMID: 32489363 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
​Emergency providers expeditiously sift and sort patients on their shifts and streamline procedures like how to place an ear wick in a patient with otitis externa, a quick and useful procedure for a patient who will reap the rewards.Standard ear wicks. The material is made from a dehydrated sponge composed of hydroxylated poly(vinyl acetate). It increases in size when liquid is applied. Photo by M. Roberts.Otitis externa can cause significant swelling, irritation, pruritis, and pain to the ear canal. Occasionally, the canal is so swollen it may be difficult to administer ear drops. An ear wick can be inserted between the...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Publication date: June 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 6Author(s): Eun Lee, So-Yeon Lee, Hwan-Cheol Kim, Kil Yong Choi, Hyo-Bin Kim, Min Jee Park, Eun-Sang Rhee, Ji-Sun Yoon, Hyun-Ju Cho, Sungsu Jung, Kangmo Ahn, Kyung Won Kim, Youn Ho Sheen, Dong In Suh, Soo-Jong Hong
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: June 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 6Author(s):
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: June 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 6Author(s): Takashi Nomura, Jianni Wu, Kenji Kabashima, Emma Guttman-Yassky
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Are those with atopic dermatitis more likely to develop food allergies?Current Opinion in Allergy and Clinical Immunology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Allergy & Clinical Immunology Journal Article Source Type: news
ConclusionsSensitization to skin resident fungi includingMalassezia globosa is uncommon in European CholU patients, but is associated with atopy and pronounced wheal formation upon dermal contact with their own sweat.Trial registration German Clinical Trials Registry DRKS-ID: DRKS00004277
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
The fundamental defect(s) that drives atopic dermatitis (AD) remains controversial. “Outside in” proponents point to the important association of filaggrin gene mutations and other skin barrier defects with AD. The “inside out” proponents derive support from evidence that AD occurs in genetic animal models with overexpression of type 2 immune pathways in their skin, and hum ans with gain-of-function mutations in their type 2 response develop severe AD. The observation that therapeutic biologics, targeting type 2 immune responses, can reverse AD provides compelling support for the importance of &ldqu...
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Reviews and feature articles Source Type: research
Chronic pruritus, or itch lasting>6 weeks, is a common symptom and has a profoundly negative impact on quality of life. While many primary dermatologic disorders such as atopic dermatitis and chronic urticaria are characterized by pruritus, numerous other allergic, hepatobiliary, lymphoproliferative, neurologic, and renal disorders are associated with chronic pruritus. Itch involves complex interactions orchestrated by a variety of factors released from and acting on the skin, immune system, and the sensory nervous system.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research
Authors: Nowicki RJ, Trzeciak M, Kaczmarski M, Wilkowska A, Czarnecka-Operacz M, Kowalewski C, Rudnicka L, Kulus M, Mastalerz-Migas A, Peregud-Pogorzelski J, Sokołowska-Wojdyło M, Śpiewak R, Adamski Z, Czuwara J, Kapińska-Mrowiecka M, Kaszuba A, Krasowska D, Krêcisz B, Narbutt J, Majewski S, Reich A, Samochocki Z, Szepietowski J, Woźniak K Abstract Atopic dermatitis is a chronic and recurrent inflammatory dermatosis with concomitant intensive pruritus, and is diagnosed both in children and adults. Atopic dermatitis-patients are predisposed to have bacterial, viral and fungal skin infections; they also su...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
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