Molecules, Vol. 27, Pages 6360: Phytochemical Composition, Antibacterial, Antioxidant and Antidiabetic Potentials of Cydonia oblonga Bark
The objective of this study was to evaluate the phytochemical composition, and antibacterial, antioxidant, and ant-diabetic potentials of methanolic extracts of Cydonia oblonga bark. The Cydonia oblonga bark extraction was fractionated through HPLC and seven purified fractions labeled as F1, F2, F3, F4, F5, F6, and F7 were obtained. The HPLC-UV analysis of methanolic extract showed the presence of a number of possible compounds. The GC-MS and HPLC analysis confirmed the presence of the following bioactive compounds in the crude extract and purified fractions: malic acid, mandelic acid, quercetin, caffeic acid, catechin hyd...
Source: Molecules - September 26, 2022 Category: Chemistry Authors: Shaymaa Najm Abed Sania Bibi Marwa Jan Muhammad Talha Noor Ul Islam Muhammad Zahoor Fakhria A. Al-Joufi Tags: Article Source Type: research
UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang < em > Cydonia oblonga < /em > Mill. for Antiatherosclerosis
In this study, the quality markers of quince were investigated by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method and network pharmacology method to highlight the three core elements which are, respectively, traceability transmission, measurability, and validity. At the first step, 72 components were identified by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method. In the next step, 46 candidate components of COM anti-AS were obtained by network pharmacology, and then, 27 active components were filte...
Source: Biomed Res - June 7, 2022 Category: Research Authors: Jimilihan Simayi Abulaiti Abulizi Maimaitiming Nuermaimaiti Nawaz Khan Sendaer Hailati Mengyuan Han Ziruo Talihati Kayisaier Abudurousuli Nulibiya Maihemuti Muhadaisi Nuer Wenting Zhou Ainiwaer Wumaier Source Type: research
UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang < em > Cydonia oblonga < /em > Mill. for Antiatherosclerosis
In this study, the quality markers of quince were investigated by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method and network pharmacology method to highlight the three core elements which are, respectively, traceability transmission, measurability, and validity. At the first step, 72 components were identified by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method. In the next step, 46 candidate components of COM anti-AS were obtained by network pharmacology, and then, 27 active components were filte...
Source: Atherosclerosis - June 7, 2022 Category: Cardiology Authors: Jimilihan Simayi Abulaiti Abulizi Maimaitiming Nuermaimaiti Nawaz Khan Sendaer Hailati Mengyuan Han Ziruo Talihati Kayisaier Abudurousuli Nulibiya Maihemuti Muhadaisi Nuer Wenting Zhou Ainiwaer Wumaier Source Type: research
UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang < em > Cydonia oblonga < /em > Mill. for Antiatherosclerosis
In this study, the quality markers of quince were investigated by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method and network pharmacology method to highlight the three core elements which are, respectively, traceability transmission, measurability, and validity. At the first step, 72 components were identified by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method. In the next step, 46 candidate components of COM anti-AS were obtained by network pharmacology, and then, 27 active components were filte...
Source: Biomed Res - June 7, 2022 Category: Research Authors: Jimilihan Simayi Abulaiti Abulizi Maimaitiming Nuermaimaiti Nawaz Khan Sendaer Hailati Mengyuan Han Ziruo Talihati Kayisaier Abudurousuli Nulibiya Maihemuti Muhadaisi Nuer Wenting Zhou Ainiwaer Wumaier Source Type: research
UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang < em > Cydonia oblonga < /em > Mill. for Antiatherosclerosis
In this study, the quality markers of quince were investigated by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method and network pharmacology method to highlight the three core elements which are, respectively, traceability transmission, measurability, and validity. At the first step, 72 components were identified by applying the ultraperformance liquid chromatography-time-of-flight mass spectrometry (UHPLC/Q-TOF-MS/MS) method. In the next step, 46 candidate components of COM anti-AS were obtained by network pharmacology, and then, 27 active components were filte...
Source: Atherosclerosis - June 7, 2022 Category: Cardiology Authors: Jimilihan Simayi Abulaiti Abulizi Maimaitiming Nuermaimaiti Nawaz Khan Sendaer Hailati Mengyuan Han Ziruo Talihati Kayisaier Abudurousuli Nulibiya Maihemuti Muhadaisi Nuer Wenting Zhou Ainiwaer Wumaier Source Type: research
Clinical Efficacy of Persian Medicine Diet Combined with Western Medicine-Based Diet on Proteinuria in Pediatric Nephrotic Syndrome: A Randomized Controlled Clinical Trial
CONCLUSION: The results of this study showed that adding dietary recommendations of the Persian medicine to the general rules of the Western medicine diet reduced proteinuria and improved the combat against nephrotic syndrome.PMID:35656469 | PMC:PMC9155912 | DOI:10.1155/2022/2279209 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - June 3, 2022 Category: Complementary Medicine Authors: Alireza Rahmani Mohsen Naseri Masoumeh Mohkam Monireh Sadat Motaharifard Mahsa Bakhtiary Nezhat Shakeri Reza Ilkhani Source Type: research
Volatile Constituents of Some Selected Plant Species Traditionally Used as Tea in the Sharri Mountains (Kosovo)
ScientificWorldJournal. 2022 May 16;2022:2594195. doi: 10.1155/2022/2594195. eCollection 2022.ABSTRACTThe study evaluates the chemical composition of the volatile constituents of ten plant species traditionally used as herbal tea in the Sharri Mountain regions (Kosovo and North Macedonia). Volatile constituents responsible for the flavour and fragrance of selected species (Crataegus monogyna, Cydonia oblonga, Malus sylvestris, Matricaria chamomilla, Morus alba, Morus nigra, Rosa canina, Sambucus nigra, Tilia cordata, and Vaccinium myrtillus) were separated and then identified using GC-MS, whereas GC-FID is employed for the...
Source: The Scientific World Journal - May 26, 2022 Category: Science Authors: Avni Hajdari Nita Kelmendi Genista Mustafa Behxhet Mustafa Dashnor Nebija Source Type: research
Molecules, Vol. 27, Pages 2462: Phenolic Acids and Flavonoids in Acetonic Extract from Quince (Cydonia oblonga Mill.): Nutraceuticals with Antioxidant and Anti-Inflammatory Potential
In this study polyphenols from quince fruit were extracted with aqueous acetone at different ratios. A polyphenol profile was identified and quantified by LC-ESI-QqQ. The antioxidant capacity (ORAC and DPPH) and anti-inflammatory effect (inhibition of COX-2 cyclooxygenase) were evaluated in vitro. The results indicated an effect of the aqueous acetone ratio on the extraction of polyphenolic compounds. The higher extraction yields of polyphenolic compounds were attained with 60&ndash;75% aqueous acetone. However, extracts obtained with 85% aqueous acetone promoted higher antioxidant and anti-inflammatory effects. Op...
Source: Molecules - April 11, 2022 Category: Chemistry Authors: Karen Marlenne Herrera-Rocha Nuria Elizabeth Rocha-Guzm án Jos é Alberto Gallegos-Infante Rub én Francisco González-Laredo Mar Larrosa-P érez Martha Roc ío Moreno-Jiménez Tags: Article Source Type: research
Nano-hydroxyapatite incorporated quince seed mucilage bioscaffolds for osteogenic differentiation of human adipose-derived mesenchymal stem cells
In this study, the therapeutic hydrocolloid quince seed mucilage (QSM) from Cydonia oblonga Miller fruit is enriched with needle-like nano-hydroxyapatite (nHAp) crystals to fabricate a novel biomimetic osteogenic bioscaffold. The molecular weight (Mw) of water-based extracted QSM was measured with GPC (8.67 × 105 g/mol), and the composite blend was prepared at a ratio of 1:1 (w/w) QSMaq and nHAp. The porous bioscaffolds were manufactured by the freeze-drying method, and evaluated in-depth with advanced analyses. The XRD, ATR-FTIR, SEM-EDX, and elemental mapping analyses revealed a uniform coated semi-crystalline structure...
Source: International Journal of Biological Macromolecules - December 18, 2021 Category: Biochemistry Authors: Cigdem Cetin Genc Hilal Deniz Yilmaz Burak Karaca Fadime Kiran Yavuz Emre Arslan Source Type: research
3D printing and properties of cellulose nanofibrils-reinforced quince seed mucilage bio-inks
Int J Biol Macromol. 2021 Oct 16;192:1098-1107. doi: 10.1016/j.ijbiomac.2021.10.078. Online ahead of print.ABSTRACTPlant-based hydrogels have attracted great attention in biomedical fields since they are biocompatible and based on natural, sustainable, cost-effective, and widely accessible sources. Here, we introduced new viscoelastic bio-inks composed of quince seed mucilage and cellulose nanofibrils (QSM/CNF) easily extruded into 3D lattice structures through direct ink writing in ambient conditions. The QSM/CNF inks enabled precise control on printing fidelity where CNF endowed objects with shape stability after freeze-...
Source: International Journal of Biological Macromolecules - October 19, 2021 Category: Biochemistry Authors: Hossein Baniasadi Roberta Teixeira Polez Erfan Kimiaei Zahraalsadat Madani Orlando J Rojas Monika Österberg Jukka Sepp älä Source Type: research
