Exploring the antibacterial potential of magnetite/quince seed mucilage/ag nanocomposite: Synthesis, characterization, and activity assessment
In this study, we present a novel core-shell antibacterial agent designed for water disinfection purposes. The nanocomposite is synthesized by combining quince seed mucilage (QSM) as the shell material and Fe3O4 as the core material. The integration of antibacterial silver nanoparticles (Ag NPs) onto the QSM shell effectively prevents agglomeration of the Ag NPs, resulting in a larger contact surface area with bacteria and consequently exhibiting enhanced antibacterial activity. The incorporation of magnetic Fe3O4 NPs with a saturation magnetization of 55.2 emu·g-1 as the core allows for easy retrieval of the nanocomposit...
Source: International Journal of Biological Macromolecules - August 4, 2023 Category: Biochemistry Authors: Ahmad Reza Gharaati Alireza Allafchian Fathallah Karimzadeh Source Type: research

Exploration of curcumin-incorporated dual anionic alginate-quince seed gum films for transdermal drug delivery
Int J Biol Macromol. 2023 Jul 11:125798. doi: 10.1016/j.ijbiomac.2023.125798. Online ahead of print.ABSTRACTThe idea of combining bioextracted polymers for wound healing applications has emerged in hopes of developing highly flexible and mechanically stable hydrogel films with controlled drug delivery, biocompatibility, and high collagen deposition. In the present research, polysaccharide films composed of Alginate and Quince Seed Gum (QSG) were fabricated by ionic crosslinking, and their potential for curcumin delivery and wound healing were examined. In this regard, microstructure, mechanical properties, thermal stabilit...
Source: International Journal of Biological Macromolecules - July 13, 2023 Category: Biochemistry Authors: Amir Abbas Abedini Gholamreza Pircheraghi Alireza Kaviani Saadi Hosseini Source Type: research

Structural characterization of lignin-carbohydrate complexes from Chinese quince fruits extracted after enzymatic hydrolysis pretreatment
In this study, to elucidate the structural characteristics of the original LCC formed by lignin and pectin in CQF, single and multiple enzymatic hydrolysis pretreatments were innovatively performed, and the resulting LCC preparations were comprehensively characterized using a series of techniques. The enzymatic hydrolysis pretreatments significantly increase the LCC yield, releasing LCC fractions with low molecular weights (Mw = 4660-8288 Da). LCC-4, isolated by pretreatment with cellulase plus xylanase, had the highest galacturonic acid content (15.5 %), followed by LCC-2 (isolated by xylanase pretreatment) of 14.0 %. In ...
Source: International Journal of Biological Macromolecules - July 5, 2023 Category: Biochemistry Authors: Xi-Chuang Cheng Ya-Nan Wei Lu-Lu Yuan Zhao Qin Hua-Min Liu Xue-De Wang Source Type: research

Biosynthesis of Gold Nanoparticles Using Quince Seed Water Extract and Investigation of Their Anticancer Effect Against Cancer Cell Lines
In this study, gold nanoparticles (Au-NPs) were synthesized using HAuCl4 and quince seed mucilage (QSM) extract, which was characterized by conventional methods including Fourier transforms electron microscopy (FTIR), UV-Visible spectroscopy (UV-Vis), Field emission electron microscopy (FESEM), Transmission electron microscopy (TEM), Dynamic light spectroscopy (DLS), and Zeta-potential. The QSM acted as reductant and stabilizing agents simultaneously. The NP’s anticancer activity was also investigated against osteosarcoma cell lines (MG-63), which showed an IC50 of $317 \mu \text{g}$ /mL. (Source: IEE Transactions on NanoBioscience)
Source: IEE Transactions on NanoBioscience - June 28, 2023 Category: Nanotechnology Source Type: research

Design and fabrication of magnetic Fe < sub > 3 < /sub > O < sub > 4 < /sub > -QSM nanoparticles loaded with ciprofloxacin as a potential antibacterial agent
Int J Biol Macromol. 2023 Apr 21:124517. doi: 10.1016/j.ijbiomac.2023.124517. Online ahead of print.ABSTRACTIn this investigation, we have synthesized magnetite nanoparticles (Fe3O4 NPs) coated with quince seed mucilage (QSM) as a natural, biocompatible, and biodegradable component and loaded them with ciprofloxacin (CIP) to act as an antibacterial agent. The structural, magnetic, physicochemical, colloidal, and antibacterial properties of the samples were tested using various characterization tools such as XRD, TEM, FE-SEM, VSM, FT-IR, UV-Vis, DLS, BET, and disk diffusion for testing the antibacterial properties. XRD and ...
Source: International Journal of Biological Macromolecules - April 23, 2023 Category: Biochemistry Authors: Mehdi Shirazi Alireza Allafchian Hadi Salamati Source Type: research

Design and fabrication of magnetic Fe < sub > 3 < /sub > O < sub > 4 < /sub > -QSM nanoparticles loaded with ciprofloxacin as a potential antibacterial agent
Int J Biol Macromol. 2023 Apr 21:124517. doi: 10.1016/j.ijbiomac.2023.124517. Online ahead of print.ABSTRACTIn this investigation, we have synthesized magnetite nanoparticles (Fe3O4 NPs) coated with quince seed mucilage (QSM) as a natural, biocompatible, and biodegradable component and loaded them with ciprofloxacin (CIP) to act as an antibacterial agent. The structural, magnetic, physicochemical, colloidal, and antibacterial properties of the samples were tested using various characterization tools such as XRD, TEM, FE-SEM, VSM, FT-IR, UV-Vis, DLS, BET, and disk diffusion for testing the antibacterial properties. XRD and ...
Source: International Journal of Biological Macromolecules - April 21, 2023 Category: Biochemistry Authors: Mehdi Shirazi Alireza Allafchian Hadi Salamati Source Type: research

Design and fabrication of magnetic Fe < sub > 3 < /sub > O < sub > 4 < /sub > -QSM nanoparticles loaded with ciprofloxacin as a potential antibacterial agent
Int J Biol Macromol. 2023 Apr 21:124517. doi: 10.1016/j.ijbiomac.2023.124517. Online ahead of print.ABSTRACTIn this investigation, we have synthesized magnetite nanoparticles (Fe3O4 NPs) coated with quince seed mucilage (QSM) as a natural, biocompatible, and biodegradable component and loaded them with ciprofloxacin (CIP) to act as an antibacterial agent. The structural, magnetic, physicochemical, colloidal, and antibacterial properties of the samples were tested using various characterization tools such as XRD, TEM, FE-SEM, VSM, FT-IR, UV-Vis, DLS, BET, and disk diffusion for testing the antibacterial properties. XRD and ...
Source: International Journal of Biological Macromolecules - April 21, 2023 Category: Biochemistry Authors: Mehdi Shirazi Alireza Allafchian Hadi Salamati Source Type: research

Molecules, Vol. 28, Pages 3066: Changes in Physicochemical and Bioactive Properties of Quince (Cydonia oblonga Mill.) and Its Products
kadiusz Szterk Quince (Cydonia oblonga Miller) is a plant that is commonly cultivated around the world, known for centuries for its valuable nutritional and healing properties. Although quince fruit are extremely aromatic, due to their high hardness and sour, astringent, and bitter taste, they are not suitable for direct consumption in an unprocessed form. However, they are an important raw material in fruit processing, e.g., in the production of jams, jellies, and juices. Quince fruits fall under the category of temperate fruits, so their shelf life can be predicted. Considering that technological processing affects n...
Source: Molecules - March 29, 2023 Category: Chemistry Authors: Katarzyna Najman Sylwia Adrian Anna Sadowska Katarzyna Świąder Ewelina Hallmann Krzysztof Buczak Bo żena Waszkiewicz-Robak Arkadiusz Szterk Tags: Article Source Type: research

Interaction between Chinese quince fruit proanthocyanidins and bovine serum albumin: Antioxidant activity, thermal stability and heterocyclic amine inhibition
In this study, two PAs (F1 and F2) with different degrees of polymerization (DP) were extracted from Chinese quince fruits. These were combined with bovine serum albumin (BSA). The thermal stability, antioxidant capacity and HCAs inhibition of all four (F1, F2, F1-BSA, F2-BSA) were compared. The results showed that F1 and F2 interact with BSA to form complexes. Circular dichroism spectra indicate that complexes had fewer α-helices and more β-sheets, β-turns and random coils than BSA. Molecular docking studies indicated that hydrogen bonds and hydrophobic interactions are the forces holding the complexes together. The th...
Source: International Journal of Biological Macromolecules - March 18, 2023 Category: Biochemistry Authors: Hui-Hui Gao Nai-Chang Hou Xin Gao Jing-Yang Yuan Wan-Qing Kong Chen-Xia Zhang Zhao Qin Hua-Min Liu Xue-De Wang Source Type: research

Interaction between Chinese quince fruit proanthocyanidins and bovine serum albumin: Antioxidant activity, thermal stability and heterocyclic amine inhibition
In this study, two PAs (F1 and F2) with different degrees of polymerization (DP) were extracted from Chinese quince fruits. These were combined with bovine serum albumin (BSA). The thermal stability, antioxidant capacity and HCAs inhibition of all four (F1, F2, F1-BSA, F2-BSA) were compared. The results showed that F1 and F2 interact with BSA to form complexes. Circular dichroism spectra indicate that complexes had fewer α-helices and more β-sheets, β-turns and random coils than BSA. Molecular docking studies indicated that hydrogen bonds and hydrophobic interactions are the forces holding the complexes together. The th...
Source: International Journal of Biological Macromolecules - March 18, 2023 Category: Biochemistry Authors: Hui-Hui Gao Nai-Chang Hou Xin Gao Jing-Yang Yuan Wan-Qing Kong Chen-Xia Zhang Zhao Qin Hua-Min Liu Xue-De Wang Source Type: research

Investigation of the mixing ratio of quince seed gum, potato starch and gellan gum on the properties of the resulting film by Mixture Design
In this study, the impact of three different biopolymers, namely, quince seed gum, potato starch and gellan gum, at levels of zero to three, on optimizing the biodegradable film was investigated. In order to prepare the mixed edible film, the textural properties of the films, water vapor permeability, water-solubility, transparency, thickness, color parameters, acid solubility and microstructure of the made films were investigated. Numerical optimization of method variables was performed based on the maximum Young's modulus and minimum solubility in water, minimum solubility in acid and minimum water vapor permeability by ...
Source: International Journal of Biological Macromolecules - March 5, 2023 Category: Biochemistry Authors: Pegah Hosseini Mohammad Hojjatoleslamy Hooman Molavi Source Type: research

Investigation of the mixing ratio of quince seed gum, potato starch and gellan gum on the properties of the resulting film by Mixture Design
In this study, the impact of three different biopolymers, namely, quince seed gum, potato starch and gellan gum, at levels of zero to three, on optimizing the biodegradable film was investigated. In order to prepare the mixed edible film, the textural properties of the films, water vapor permeability, water-solubility, transparency, thickness, color parameters, acid solubility and microstructure of the made films were investigated. Numerical optimization of method variables was performed based on the maximum Young's modulus and minimum solubility in water, minimum solubility in acid and minimum water vapor permeability by ...
Source: International Journal of Biological Macromolecules - March 5, 2023 Category: Biochemistry Authors: Pegah Hosseini Mohammad Hojjatoleslamy Hooman Molavi Source Type: research

Quince extract resists atherosclerosis in rats by down-regulating the EGFR/PI3K/Akt/GSK-3 β pathway
Biomed Pharmacother. 2023 Feb 4;160:114330. doi: 10.1016/j.biopha.2023.114330. Online ahead of print.ABSTRACTWe identified the effective components and the underlying mechanisms of Quince (Cydonia oblonga Mill, COM) extract against atherosclerosis. The effective components of COM extract were identified with UHPLC-Q-TOF-MS/MS. Network pharmacology was performed. A rat model of atherosclerosis induced by high-fat emulsion combined with vitamin D3 was established. The anti-atherosclerosis effect of COM extract was evaluated from various aspects such as blood lipid regulation, anti-oxidative stress, anti-inflammatory response...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 6, 2023 Category: Drugs & Pharmacology Authors: Abulaiti Abulizi Jimilihan Simayi Maimaitiming Nuermaimaiti Mengyuan Han Sendaer Hailati Ziruo Talihati Nulibiya Maihemuti Muhadaisi Nuer Nawaz Khan Kayisaier Abudurousuli Dilihuma Dilimulati Nuerbiye Nueraihemaiti Nicholas Moore Ainiwaer Wumaier Wenting Source Type: research

Quince extract resists atherosclerosis in rats by down-regulating the EGFR/PI3K/Akt/GSK-3 β pathway
Biomed Pharmacother. 2023 Feb 4;160:114330. doi: 10.1016/j.biopha.2023.114330. Online ahead of print.ABSTRACTWe identified the effective components and the underlying mechanisms of Quince (Cydonia oblonga Mill, COM) extract against atherosclerosis. The effective components of COM extract were identified with UHPLC-Q-TOF-MS/MS. Network pharmacology was performed. A rat model of atherosclerosis induced by high-fat emulsion combined with vitamin D3 was established. The anti-atherosclerosis effect of COM extract was evaluated from various aspects such as blood lipid regulation, anti-oxidative stress, anti-inflammatory response...
Source: Atherosclerosis - February 6, 2023 Category: Cardiology Authors: Abulaiti Abulizi Jimilihan Simayi Maimaitiming Nuermaimaiti Mengyuan Han Sendaer Hailati Ziruo Talihati Nulibiya Maihemuti Muhadaisi Nuer Nawaz Khan Kayisaier Abudurousuli Dilihuma Dilimulati Nuerbiye Nueraihemaiti Nicholas Moore Ainiwaer Wumaier Wenting Source Type: research

Cardiovascular Effects of < em > Cydonia oblonga < /em > Miller (Quince)
This study paves the way for further studies on the cardiovascular effect of quince consumption as a beneficial nutraceutical in humans.PMID:36262168 | PMC:PMC9576383 | DOI:10.1155/2022/3185442 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - October 20, 2022 Category: Complementary Medicine Authors: Atefeh Amerizadeh Golnaz Vaseghi Nazgol Esmaeilian Sedigheh Asgary Source Type: research