NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research
Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients
CONCLUSIONS: This study demonstrates that MAC may be considered for select pediatric patients undergoing endoscopic removal of EFB, especially those who have ingested coins, who do not have reactive airways, who have fasted for >6 h, and in whom the endoscopic procedure is expected to be short and uncomplicated. Prospective multi-site studies are needed to confirm these findings.PMID:38591665 | DOI:10.1111/pan.14888 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 9, 2024 Category: Anesthesiology Authors: Hannah Lonsdale Kurt Rodriguez Ryan Shargo Morgan Ekblad Jerry M Brown Isabella Dolan Jamie L Fierstein Alexandra Miller Aditi Dey Jacquelin Peck Mohamed A Rehman Michael J Wilsey Source Type: research
Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients
CONCLUSIONS: This study demonstrates that MAC may be considered for select pediatric patients undergoing endoscopic removal of EFB, especially those who have ingested coins, who do not have reactive airways, who have fasted for >6 h, and in whom the endoscopic procedure is expected to be short and uncomplicated. Prospective multi-site studies are needed to confirm these findings.PMID:38591665 | DOI:10.1111/pan.14888 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 9, 2024 Category: Anesthesiology Authors: Hannah Lonsdale Kurt Rodriguez Ryan Shargo Morgan Ekblad Jerry M Brown Isabella Dolan Jamie L Fierstein Alexandra Miller Aditi Dey Jacquelin Peck Mohamed A Rehman Michael J Wilsey Source Type: research
Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients
CONCLUSIONS: This study demonstrates that MAC may be considered for select pediatric patients undergoing endoscopic removal of EFB, especially those who have ingested coins, who do not have reactive airways, who have fasted for >6 h, and in whom the endoscopic procedure is expected to be short and uncomplicated. Prospective multi-site studies are needed to confirm these findings.PMID:38591665 | DOI:10.1111/pan.14888 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 9, 2024 Category: Anesthesiology Authors: Hannah Lonsdale Kurt Rodriguez Ryan Shargo Morgan Ekblad Jerry M Brown Isabella Dolan Jamie L Fierstein Alexandra Miller Aditi Dey Jacquelin Peck Mohamed A Rehman Michael J Wilsey Source Type: research
Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients
CONCLUSIONS: This study demonstrates that MAC may be considered for select pediatric patients undergoing endoscopic removal of EFB, especially those who have ingested coins, who do not have reactive airways, who have fasted for >6 h, and in whom the endoscopic procedure is expected to be short and uncomplicated. Prospective multi-site studies are needed to confirm these findings.PMID:38591665 | DOI:10.1111/pan.14888 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 9, 2024 Category: Anesthesiology Authors: Hannah Lonsdale Kurt Rodriguez Ryan Shargo Morgan Ekblad Jerry M Brown Isabella Dolan Jamie L Fierstein Alexandra Miller Aditi Dey Jacquelin Peck Mohamed A Rehman Michael J Wilsey Source Type: research
Screening of potential biomarkers in propofol-induced neurotoxicity via bioinformatics prediction and experimental verification
CONCLUSIONS: Previous studies have demonstrated that EGR4, HAO1, ITK and GM14446 play a role in intellectual development, neuroinflammation and neuronal differentiation. These hub genes may help us to find new preventive and therapeutic targets for propofol-induced neurotoxicity.PMID:38586100 | PMC:PMC10994811 | DOI:10.62347/MTAY7931 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Tianping He Jianfeng Huang Bo Peng Mianhui Wang Qiuhao Shui Liang Cai Source Type: research
