Dexmedetomidine Pretreatment Confers Myocardial Protection and Reduces Mechanical Ventilation Duration for Patients Undergoing Cardiac Valve Replacement under Cardiopulmonary Bypass
CONCLUSION: The study suggests that 0.50 µg/kg Dex pretreatment could reduce propofol use and the duration of mechanical ventilation, and confer myocardial protection without increased adverse events during cardiac valve replacement.PMID:38684422 | DOI:10.5761/atcs.oa.23-00210 (Source: Annals of Thoracic and Cardiovascular Surgery)
Source: Annals of Thoracic and Cardiovascular Surgery - April 29, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Binglin Yuan Xiqiang Huang Junlin Wen Mengzhe Peng Source Type: research

To Compare the Anesthetic Effect of Remimazolam and Propofol in Painless Hysteroscopic Minimally Invasive Surgery
CONCLUSION: Intravenous induction of remimazolam at 6 mg·kg-1·h-1 and maintenance of anesthesia at 1-2 mg·kg-1·h-1 have less effect on hemodynamics, faster recovery time and lower incidence of adverse reactions compared with propofol when used in minimally invasive hysteroscopic surgery. Remimazolam can be safely and effectively used in this kind of surgery.PMID:38684498 | DOI:10.62713/aic.3291 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Fei Gao Yanjun Xie Hengwei Zhu Chen Chen Hongyan Fu Source Type: research

Dexmedetomidine Pretreatment Confers Myocardial Protection and Reduces Mechanical Ventilation Duration for Patients Undergoing Cardiac Valve Replacement under Cardiopulmonary Bypass
CONCLUSION: The study suggests that 0.50 µg/kg Dex pretreatment could reduce propofol use and the duration of mechanical ventilation, and confer myocardial protection without increased adverse events during cardiac valve replacement.PMID:38684422 | PMC:PMC11082494 | DOI:10.5761/atcs.oa.23-00210 (Source: Annals of Thoracic and Cardiovascular Surgery)
Source: Annals of Thoracic and Cardiovascular Surgery - April 29, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Binglin Yuan Xiqiang Huang Junlin Wen Mengzhe Peng Source Type: research

To Compare the Anesthetic Effect of Remimazolam and Propofol in Painless Hysteroscopic Minimally Invasive Surgery
CONCLUSION: Intravenous induction of remimazolam at 6 mg·kg-1·h-1 and maintenance of anesthesia at 1-2 mg·kg-1·h-1 have less effect on hemodynamics, faster recovery time and lower incidence of adverse reactions compared with propofol when used in minimally invasive hysteroscopic surgery. Remimazolam can be safely and effectively used in this kind of surgery.PMID:38684498 | DOI:10.62713/aic.3291 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Fei Gao Yanjun Xie Hengwei Zhu Chen Chen Hongyan Fu Source Type: research

Dexmedetomidine Pretreatment Confers Myocardial Protection and Reduces Mechanical Ventilation Duration for Patients Undergoing Cardiac Valve Replacement under Cardiopulmonary Bypass
CONCLUSION: The study suggests that 0.50 µg/kg Dex pretreatment could reduce propofol use and the duration of mechanical ventilation, and confer myocardial protection without increased adverse events during cardiac valve replacement.PMID:38684422 | PMC:PMC11082494 | DOI:10.5761/atcs.oa.23-00210 (Source: Annals of Thoracic and Cardiovascular Surgery)
Source: Annals of Thoracic and Cardiovascular Surgery - April 29, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Binglin Yuan Xiqiang Huang Junlin Wen Mengzhe Peng Source Type: research

To Compare the Anesthetic Effect of Remimazolam and Propofol in Painless Hysteroscopic Minimally Invasive Surgery
CONCLUSION: Intravenous induction of remimazolam at 6 mg·kg-1·h-1 and maintenance of anesthesia at 1-2 mg·kg-1·h-1 have less effect on hemodynamics, faster recovery time and lower incidence of adverse reactions compared with propofol when used in minimally invasive hysteroscopic surgery. Remimazolam can be safely and effectively used in this kind of surgery.PMID:38684498 | DOI:10.62713/aic.3291 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Fei Gao Yanjun Xie Hengwei Zhu Chen Chen Hongyan Fu Source Type: research

Dexmedetomidine Pretreatment Confers Myocardial Protection and Reduces Mechanical Ventilation Duration for Patients Undergoing Cardiac Valve Replacement under Cardiopulmonary Bypass
CONCLUSION: The study suggests that 0.50 µg/kg Dex pretreatment could reduce propofol use and the duration of mechanical ventilation, and confer myocardial protection without increased adverse events during cardiac valve replacement.PMID:38684422 | PMC:PMC11082494 | DOI:10.5761/atcs.oa.23-00210 (Source: Annals of Thoracic and Cardiovascular Surgery)
Source: Annals of Thoracic and Cardiovascular Surgery - April 29, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Binglin Yuan Xiqiang Huang Junlin Wen Mengzhe Peng Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Mol Biol Cell - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research

In Vitro Hepatotoxicity of Routinely Used Opioids and Sedative Drugs
Curr Issues Mol Biol. 2024 Mar 30;46(4):3022-3038. doi: 10.3390/cimb46040189.ABSTRACTA hepatocyte cell line was used to determine the hepatotoxicity of sedatives and opioids, as the hepatotoxicity of these drugs has not yet been well characterized. This might pose a threat, especially to critically ill patients, as they often receive high cumulative doses for daily analgosedation and often already have impaired liver function due to an underlying disease or complications during treatment. A well-established biosensor based on HepG2/C3A cells was used for the determination of the hepatotoxicity of commonly used sedatives an...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Katharina Haller Sandra Do ß Martin Sauer Source Type: research