Prenatal Care: An Evidence-Based Approach
Am Fam Physician. 2023 Aug;108(2):139-150.ABSTRACTWell-coordinated prenatal care that follows an evidence-based, informed process results in fewer hospital admissions, improved education, greater satisfaction, and lower pregnancy-associated morbidity and mortality. Care initiated at 10 weeks or earlier improves outcomes. Identification and treatment of periodontal disease decreases preterm delivery risk. A prepregnancy body mass index greater than 25 kg per m2 is associated with gestational diabetes mellitus, hypertension, miscarriage, and stillbirth. Advanced maternal and paternal age (35 years or older) is associated wit...
Source: American Family Physician - August 17, 2023 Category: Primary Care Authors: Sarah In és Ramírez Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

Whole Blood Administration for Obstetric-Related Hemorrhage During Prehospital Transport
CONCLUSION: Whole blood can be successfully administered both in and out of the hospital setting, even for obstetric hemorrhage. The benefits of easily administered balanced resuscitation, limited donor exposure, and improved patient outcomes likely outweigh potential alloimmunization, especially in resource-limited settings. Addressing concerns of alloimmunization cannot be accomplished without more research, and we encourage others to investigate using whole blood in this population.PMID:37562035 | DOI:10.1097/AOG.0000000000005320 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 10, 2023 Category: OBGYN Authors: Abigail Polzin Kaihlen Smith Thomas Rumpza Source Type: research

In-vivo and human evidence for potential efficacy of therapeutic polyclonal RSV neutralizing antibodies for palivizumab-resistant RSV infections
CONCLUSIONS: RSV-IG and ribavirin use in immunocompromised patients requires further study.PMID:37542818 | DOI:10.1016/j.virol.2023.07.007 (Source: Virology)
Source: Virology - August 5, 2023 Category: Virology Authors: Kacy A Ramirez James Mond Jesse Papenburg Guy Boivin Brian E Gilbert Ann R Falsey Bindiya Bagga John P DeVincenzo Source Type: research

In-vivo and human evidence for potential efficacy of therapeutic polyclonal RSV neutralizing antibodies for palivizumab-resistant RSV infections
CONCLUSIONS: RSV-IG and ribavirin use in immunocompromised patients requires further study.PMID:37542818 | DOI:10.1016/j.virol.2023.07.007 (Source: Virology)
Source: Virology - August 5, 2023 Category: Virology Authors: Kacy A Ramirez James Mond Jesse Papenburg Guy Boivin Brian E Gilbert Ann R Falsey Bindiya Bagga John P DeVincenzo Source Type: research

News at a glance: Long Covid trials, fossil controversy, and an ancient necklace restored
PALEONTOLOGY Call for fossil’s return to Brazil Paleontologists from Brazil and Europe have published an open letter asking the German state of Baden-Württemberg to return a fossil of the dinosaur Irritator challengeri (illustration above) to Brazil. The remnant of the spinosaurid’s skull was discovered in Brazil and purchased from a fossil digger by the State Museum of Natural History Stuttgart in 1991; researchers used it to describe the species in a 1996 paper. But the authors of the open letter question the legality of the export to Germany, pointing to a 1942 Brazilian...
Source: Science of Aging Knowledge Environment - August 3, 2023 Category: Geriatrics Source Type: research

Preemptive immune globulin therapy in sensitized lung transplant recipients
CONCLUSION: These findings are hypothesis generating and emphasize the need for larger, randomized studies to determine association of immune globulin therapy with clinical outcomes.PMID:37499884 | DOI:10.1016/j.trim.2023.101904 (Source: Transplant Immunology)
Source: Transplant Immunology - July 27, 2023 Category: Transplant Surgery Authors: Jessica Goldsby Kristi Beermann Courtney Frankel Alice Parish Nicolas Stauffer Amanda Schandert Alaattin Erkanli John M Reynolds Source Type: research

Preemptive immune globulin therapy in sensitized lung transplant recipients
CONCLUSION: These findings are hypothesis generating and emphasize the need for larger, randomized studies to determine association of immune globulin therapy with clinical outcomes.PMID:37499884 | DOI:10.1016/j.trim.2023.101904 (Source: Transplant Immunology)
Source: Transplant Immunology - July 27, 2023 Category: Transplant Surgery Authors: Jessica Goldsby Kristi Beermann Courtney Frankel Alice Parish Nicolas Stauffer Amanda Schandert Alaattin Erkanli John M Reynolds Source Type: research

Neutralizing activity of intravenous immune globulin products against enterovirus D68 strains isolated in Japan
Enterovirus D68 (EV-D68), belonging to Enterovirus D, is a unique human enterovirus mainly associated with common respiratory diseases. However, EV-D68 can cause severe respiratory diseases, and EV-D68 endemic is... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - July 18, 2023 Category: Infectious Diseases Authors: Kazuhiro Yoshida, Masamichi Muramatsu and Hiroyuki Shimizu Tags: Research Source Type: research

Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma
CONCLUSIONS: Awareness of the radiological findings of dinutuximab toxicity will lead to prompt diagnosis and treatment.PMID:37395971 | DOI:10.24953/turkjped.2022.598 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 3, 2023 Category: Pediatrics Authors: F ırat Atak G üzide Burça Aydın İbrahim Öncel Sibel Öz Kader Karl ı Oğuz Source Type: research

Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma
CONCLUSIONS: Awareness of the radiological findings of dinutuximab toxicity will lead to prompt diagnosis and treatment.PMID:37395971 | DOI:10.24953/turkjped.2022.598 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 3, 2023 Category: Pediatrics Authors: F ırat Atak G üzide Burça Aydın İbrahim Öncel Sibel Öz Kader Karl ı Oğuz Source Type: research