Macrophage activation syndrome with acute hepatitis in a patient with adult-onset immunodeficiency with anti-interferon gamma antibodies: a case report
ConclusionThis case highlights the importance of maintaining macrophage activation syndrome on the differential of a patient with acute hepatitis of unknown etiology in the correct clinical context and the value of a liver biopsy in making a diagnosis when noninvasive testing is unrevealing. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 5, 2024 Category: General Medicine Source Type: research
Breaking Barriers: Current Advances and Future Directions in Mpox Therapy
CONCLUSION: In this summary, we provide an overview of potential drugs that could be used to treat Mpox and discuss the underlying biological processes of their actions.PMID:38151842 | DOI:10.2174/0113894501281263231218070841 (Source: Current Drug Targets)
Source: Current Drug Targets - December 28, 2023 Category: Drugs & Pharmacology Authors: Bhumi M Shah Palmi Modi Source Type: research
Breaking Barriers: Current Advances and Future Directions in Mpox Therapy
CONCLUSION: In this summary, we provide an overview of potential drugs that could be used to treat Mpox and discuss the underlying biological processes of their actions.PMID:38151842 | DOI:10.2174/0113894501281263231218070841 (Source: Current Drug Targets)
Source: Current Drug Targets - December 28, 2023 Category: Drugs & Pharmacology Authors: Bhumi M Shah Palmi Modi Source Type: research
Effectiveness of two same-manufacturer intravenous immunoglobulin for Kawasaki disease
CONCLUSIONS: Compared with brand T, brand P prolonged the fever and hospitalization durations after IVIG treatment and increased the proportion of IVIG treatment unresponsiveness, but it did not infer the coronary arteries sequelae.PMID:38097428 | DOI:10.1016/j.jfma.2023.11.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 14, 2023 Category: General Medicine Authors: Kun-Lang Wu Ming-Tai Lin Yu-Jun Chang Source Type: research
Effectiveness of two same-manufacturer intravenous immunoglobulin for Kawasaki disease
CONCLUSIONS: Compared with brand T, brand P prolonged the fever and hospitalization durations after IVIG treatment and increased the proportion of IVIG treatment unresponsiveness, but it did not infer the coronary arteries sequelae.PMID:38097428 | DOI:10.1016/j.jfma.2023.11.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 14, 2023 Category: General Medicine Authors: Kun-Lang Wu Ming-Tai Lin Yu-Jun Chang Source Type: research
Effectiveness of two same-manufacturer intravenous immunoglobulin for Kawasaki disease
CONCLUSIONS: Compared with brand T, brand P prolonged the fever and hospitalization durations after IVIG treatment and increased the proportion of IVIG treatment unresponsiveness, but it did not infer the coronary arteries sequelae.PMID:38097428 | DOI:10.1016/j.jfma.2023.11.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 14, 2023 Category: General Medicine Authors: Kun-Lang Wu Ming-Tai Lin Yu-Jun Chang Source Type: research
Effectiveness of two same-manufacturer intravenous immunoglobulin for Kawasaki disease
CONCLUSIONS: Compared with brand T, brand P prolonged the fever and hospitalization durations after IVIG treatment and increased the proportion of IVIG treatment unresponsiveness, but it did not infer the coronary arteries sequelae.PMID:38097428 | DOI:10.1016/j.jfma.2023.11.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 14, 2023 Category: General Medicine Authors: Kun-Lang Wu Ming-Tai Lin Yu-Jun Chang Source Type: research
Effectiveness of two same-manufacturer intravenous immunoglobulin for Kawasaki disease
CONCLUSIONS: Compared with brand T, brand P prolonged the fever and hospitalization durations after IVIG treatment and increased the proportion of IVIG treatment unresponsiveness, but it did not infer the coronary arteries sequelae.PMID:38097428 | DOI:10.1016/j.jfma.2023.11.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 14, 2023 Category: General Medicine Authors: Kun-Lang Wu Ming-Tai Lin Yu-Jun Chang Source Type: research
Animal-to-Human Dose Translation of ANTHRASIL for Treatment of Inhalational Anthrax in Healthy Adults, Obese Adults, and Pediatric Subjects
Clin Pharmacol Ther. 2023 Dec 11. doi: 10.1002/cpt.3097. Online ahead of print.ABSTRACTAnthrax Immune Globulin Intravenous (AIGIV [ANTHRASIL]), was developed for the treatment of toxemia associated with inhalational anthrax. It is a plasma product collected from individuals vaccinated with anthrax vaccine and contains antitoxin IgG antibodies against Bacillus anthracis protective antigen. A pharmacokinetic (PK) and exposure-response model was constructed to assess the PKs of AIGIV in anthrax-free and anthrax-exposed rabbits, non-human primates and anthrax-free humans, as well as the relationship between AIGIV exposure and ...
Source: Clinical Pharmacology and Therapeutics - December 12, 2023 Category: Drugs & Pharmacology Authors: Martin Beliveau Igor Rubets Drobic Bojan Christine Hall Derek Toth Shantha Kodihalli Srinivas Kammanadiminti Source Type: research
Comparison of Theater Medical Data Store and Reportable Medical Event Records to Theater Animal Bite Reports Submissions, 2018-2019
CONCLUSIONS: This study is the first to compare the electronic medical record data to in theater reports for potential rabies exposure in a theater of operations. The analysis suggests that some written forms generated in the USCENTCOM theater are not entered into SM Military Health System electronic medical records, indicating that electronic medical records may be a less sensitive method than in-theatre reports for rabies program surveillance in a deployed setting. There is under-reporting in electronic medical records of rabies PEP in both TMDS and RME databases. Rabies PEP is an RME according to the Armed Forces Health...
Source: Military Medicine - November 24, 2023 Category: International Medicine & Public Health Authors: Marc G Knobbe Brandon J Aden Hayley R Ashbaugh Source Type: research
Bad Liver and a Broken Heart: Hepatitis B in the Newborn
Neonatal Netw. 2023 Nov 1;42(6):348-355. doi: 10.1891/NN-2023-0035.ABSTRACTHepatitis B viral infection is a significant source of morbidity and mortality worldwide. The United States has experienced a precipitous drop in acute hepatitis B infection after the introduction and widespread adoption of recombinant vaccines. Neonates experience significant risk from both vertical and horizontal hepatitis B exposure during a period of immaturity of the innate and adaptive immune systems. Acquisition of hepatitis B virus at or near birth confers the highest lifetime risk of chronic infection and subsequent complications including ...
Source: Neonatal Network - November 24, 2023 Category: Perinatology & Neonatology Authors: Christopher McPherson Source Type: research
Comparison of Theater Medical Data Store and Reportable Medical Event Records to Theater Animal Bite Reports Submissions, 2018-2019
CONCLUSIONS: This study is the first to compare the electronic medical record data to in theater reports for potential rabies exposure in a theater of operations. The analysis suggests that some written forms generated in the USCENTCOM theater are not entered into SM Military Health System electronic medical records, indicating that electronic medical records may be a less sensitive method than in-theatre reports for rabies program surveillance in a deployed setting. There is under-reporting in electronic medical records of rabies PEP in both TMDS and RME databases. Rabies PEP is an RME according to the Armed Forces Health...
Source: Military Medicine - November 24, 2023 Category: International Medicine & Public Health Authors: Marc G Knobbe Brandon J Aden Hayley R Ashbaugh Source Type: research
Bad Liver and a Broken Heart: Hepatitis B in the Newborn
Neonatal Netw. 2023 Nov 1;42(6):348-355. doi: 10.1891/NN-2023-0035.ABSTRACTHepatitis B viral infection is a significant source of morbidity and mortality worldwide. The United States has experienced a precipitous drop in acute hepatitis B infection after the introduction and widespread adoption of recombinant vaccines. Neonates experience significant risk from both vertical and horizontal hepatitis B exposure during a period of immaturity of the innate and adaptive immune systems. Acquisition of hepatitis B virus at or near birth confers the highest lifetime risk of chronic infection and subsequent complications including ...
Source: Neonatal Network - November 24, 2023 Category: Perinatology & Neonatology Authors: Christopher McPherson Source Type: research
Bad Liver and a Broken Heart: Hepatitis B in the Newborn
Neonatal Netw. 2023 Nov 1;42(6):348-355. doi: 10.1891/NN-2023-0035.ABSTRACTHepatitis B viral infection is a significant source of morbidity and mortality worldwide. The United States has experienced a precipitous drop in acute hepatitis B infection after the introduction and widespread adoption of recombinant vaccines. Neonates experience significant risk from both vertical and horizontal hepatitis B exposure during a period of immaturity of the innate and adaptive immune systems. Acquisition of hepatitis B virus at or near birth confers the highest lifetime risk of chronic infection and subsequent complications including ...
Source: Neonatal Network - November 24, 2023 Category: Perinatology & Neonatology Authors: Christopher McPherson Source Type: research
Comparison of Theater Medical Data Store and Reportable Medical Event Records to Theater Animal Bite Reports Submissions, 2018-2019
CONCLUSIONS: This study is the first to compare the electronic medical record data to in theater reports for potential rabies exposure in a theater of operations. The analysis suggests that some written forms generated in the USCENTCOM theater are not entered into SM Military Health System electronic medical records, indicating that electronic medical records may be a less sensitive method than in-theatre reports for rabies program surveillance in a deployed setting. There is under-reporting in electronic medical records of rabies PEP in both TMDS and RME databases. Rabies PEP is an RME according to the Armed Forces Health...
Source: Military Medicine - November 24, 2023 Category: International Medicine & Public Health Authors: Marc G Knobbe Brandon J Aden Hayley R Ashbaugh Source Type: research
