A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat
Acta Med Okayama. 2024 Feb;78(1):85-88. doi: 10.18926/AMO/66675.ABSTRACTA 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential eff...
Source: Acta Medica Okayama - February 29, 2024 Category: General Medicine Authors: Keisuke Miyake Tomohiro Tanikawa Ken Haruma Mayuko Kawada Katsunori Ishii Noriyo Urata Ken Nishino Mitsuhiko Suehiro Miwa Kawanaka Noriaki Manabe Hirofumi Kawamoto Source Type: research

Colonic spider naevi in a middle-aged man
Introduction A 59-year-old man was seen in outpatient clinic with a 1-year history of abdominal cramping and non-bloody diarrhoea. His only medical history comprised hypercholesterolaemia and oesophagogastric reflux, for which he took simvastatin and lansoprazole. He did not show cutaneous spider naevi and there was no history of liver disease or use of oestrogen or hormone replacement medications. CT of the abdomen and pelvis showed a long segment of moderate sigmoid colonic wall thickening (figure 1A) with perifocal fat stranding and free fluid in keeping with acute sigmoiditis. Feeding vessels were patent with no eviden...
Source: Gut - February 23, 2024 Category: Gastroenterology Authors: Hunter, H., Johnston, A. J., Said, W., Wong, N. A. Tags: GUT Snapshot, Gut Editor ' s quiz: GI snapshot Source Type: research

Identifying causative medications for agranulocytosis: A case report of an older adult with cerebral infarction
We present the case of a 93-year-old man who was admitted for the treatment of cerebrovascular events. The patient was initially prescribed dual antiplatelet therapy with aspirin and clopidogrel along with lansoprazole, Hange-koboku-toh, and elobixibat. On day 36 after admission, the patient was found to have developed agranulocytosis. To improve his cerebrovascular prognosis, we first discontinued medications other than the anticoagulant medicines and initiated filgrastim. We discontinued clopidogrel 9  days after the discontinuation of the other medicines considering his low white blood cell count. One day after the di...
Source: Clinical Case Reports - January 29, 2024 Category: General Medicine Authors: Yuuri Kurokawa, Ayako Watanabe, Yuka Kashiwabara, Saori Fukuda, Shohei Nomoto, Ayako Kuriki, Kenji Momo Tags: CASE REPORT Source Type: research