Response of Paenibacillus polymyxa SC2 to the stress of polymyxin B and a key ABC transporter YwjA involved
This study provides an important reference for improving the resistance of P. polymyxa to polymyxins and increasing the yield of polymyxins. KEY POINTS: • Phenotypic responses of P. polymyxa to polymyxin B was performed and indicated by RNA-seq • Forming biofilm was a key strategy of P. polymyxa to alleviate polymyxin stress • ABC transporter YwjA was involved in the stress resistance of P. polymyxa to polymyxin B.PMID:38170316 | DOI:10.1007/s00253-023-12916-3 (Source: Applied Microbiology and Biotechnology)
Source: Applied Microbiology and Biotechnology - January 3, 2024 Category: Microbiology Authors: Hui Li Wenhui E Dongying Zhao Haiyang Liu Jian Pei Binghai Du Kai Liu Xueming Zhu Chengqiang Wang Source Type: research

Response of Paenibacillus polymyxa SC2 to the stress of polymyxin B and a key ABC transporter YwjA involved
This study provides an important reference for improving the resistance of P. polymyxa to polymyxins and increasing the yield of polymyxins. KEY POINTS: • Phenotypic responses of P. polymyxa to polymyxin B was performed and indicated by RNA-seq • Forming biofilm was a key strategy of P. polymyxa to alleviate polymyxin stress • ABC transporter YwjA was involved in the stress resistance of P. polymyxa to polymyxin B.PMID:38170316 | DOI:10.1007/s00253-023-12916-3 (Source: Applied Microbiology and Biotechnology)
Source: Applied Microbiology and Biotechnology - January 3, 2024 Category: Microbiology Authors: Hui Li Wenhui E Dongying Zhao Haiyang Liu Jian Pei Binghai Du Kai Liu Xueming Zhu Chengqiang Wang Source Type: research

Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time –kill experiments: agreement with in silico predictions
ConclusionsPolymyxin B and minocycline in combination showed synergistic effects, mainly against the KPC-3-producingK. pneumoniae. The agreement between the experimental results andin silico predictions supports the use of PK/PD models based on static time –kill data to predict the activity of antibiotic combinations at dynamic drug concentrations. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - December 30, 2023 Category: Microbiology Source Type: research

Risk Factors and Outcomes for Isolation with Polymyxin B-Resistant Enterobacterales from 2018 –2022: A Case-Control Study
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - December 22, 2023 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Retracted: Polymyxin B, Cefoperazone Sodium-Sulbactam Sodium, and Tigecycline against Multidrug-Resistant < em > Acinetobacter baumannii < /em > Pneumonia
Evid Based Complement Alternat Med. 2023 Dec 13;2023:9821412. doi: 10.1155/2023/9821412. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/1968020.].PMID:38125170 | PMC:PMC10732887 | DOI:10.1155/2023/9821412 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 21, 2023 Category: Complementary Medicine Authors: Evidence-Based Complementary And Alternative Medicine Source Type: research

Specific separation and sensitive detection of foodborne pathogens by phage-derived bacterial-binding protein-nano magnetic beads coupled with smartphone-assisted paper sensor
In conclusion, this smartphone-assisted biosensor offers promising application potential for point-of-care testing (POCT) of foodborne pathogens in resource-scarce areas.PMID:38118305 | DOI:10.1016/j.bios.2023.115911 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - December 20, 2023 Category: Biotechnology Authors: Bin Hong Wenhai Wang Yanmei Li Yi Ma Jufang Wang Source Type: research

Specific separation and sensitive detection of foodborne pathogens by phage-derived bacterial-binding protein-nano magnetic beads coupled with smartphone-assisted paper sensor
In conclusion, this smartphone-assisted biosensor offers promising application potential for point-of-care testing (POCT) of foodborne pathogens in resource-scarce areas.PMID:38118305 | DOI:10.1016/j.bios.2023.115911 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - December 20, 2023 Category: Biotechnology Authors: Bin Hong Wenhai Wang Yanmei Li Yi Ma Jufang Wang Source Type: research