Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Lessons learned from the successful polio vaccine experience not learned or applied with the development and implementation of the COVID-19 vaccines
Curr Opin Immunol. 2023 Aug 29;84:102386. doi: 10.1016/j.coi.2023.102386. Online ahead of print.ABSTRACTThe eradication of polio during the latter half of the 20th century can be considered one of the greatest medical triumphs in history. This achievement can be attributed to the development of vaccines that received the public's almost unwavering acceptance of them, especially by parents who had been waiting/hoping for a medical breakthrough that would ensure that their children would not succumb to the devastating effects of infantile paralysis. Sixty years later, the worldwide population was now confronted with an equal...
Source: Current Opinion in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Charles S Pavia Maria M Plummer Source Type: research

Impact of a dTcaP booster vaccine awareness campaign initiated by the French national health insurance for adults aged 25 years in 2021
Vaccination schedules differ from country to country. In France, the diphtheria, tetanus, pertussis, poliomyelitis (dTcaP) booster vaccine coverage for adults aged 25 has been lower than those recommended. We ... (Source: BMC Health Services Research)
Source: BMC Health Services Research - August 23, 2023 Category: General Medicine Authors: Aline Hurtaud, Capucine Coomans, Brigitte Vuillemin, Akima Benamar, Maxime Couraud, Bach-Nga Pham, St éphane Sanchez and Coralie Barbe Tags: Research Source Type: research

Sabin polio virus protein 1 (VP1) evolution in patients with acute flaccid paralysis from 2010 to 2016 in Uganda
Acute flaccid paralysis (AFP) is a rare side effect of the oral polio vaccine but can be associated with outbreaks and permanent disability in patients harboring circulating vaccine-derived polioviruses (cVDPV... (Source: Virology Journal)
Source: Virology Journal - August 2, 2023 Category: Virology Authors: Mary Bridget Nanteza, Barnabas Bakamutumaho, Phionah Tushabe, Prossy Namuwulya, Molly Birungi, Rajab Dhatemwa, James Peter Eliku, Mayi Tibanagwa, Proscovia Kakooza, Henry Bukenya, Josephine Bwogi and Charles Rutebarika Byabamazima Tags: Research Source Type: research

Variability of in vivo potency assays of whole-cell pertussis, inactivated polio, and meningococcal B vaccines
Vaccine. 2023 Jul 30:S0264-410X(23)00885-X. doi: 10.1016/j.vaccine.2023.07.054. Online ahead of print.ABSTRACTFor the batch release of vaccines, potency release assays are required. Non-animal in vitro tests have numerous advantages and are preferred; however, several vaccines are still released using in vivo assays. Their major drawback is the inherent variability with its practical implications. We quantified the variability of in vivo potency release assays for whole-cell pertussis, inactivated polio and meningococcal B (MenB) vaccines which showed large CV (Coefficient of Variation) ranging from 34% to 125%. As inheren...
Source: Vaccine - August 1, 2023 Category: Allergy & Immunology Authors: Cerissa van Walstijn Stefan Verweij Rory Care Peter Rigsby Eli-Boaz Clapper Kevin Markey Rob J Vandebriel Paul Stickings Marcel H N Hoefnagel Source Type: research

Variability of in vivo potency assays of whole-cell pertussis, inactivated polio, and meningococcal B vaccines
Vaccine. 2023 Jul 30:S0264-410X(23)00885-X. doi: 10.1016/j.vaccine.2023.07.054. Online ahead of print.ABSTRACTFor the batch release of vaccines, potency release assays are required. Non-animal in vitro tests have numerous advantages and are preferred; however, several vaccines are still released using in vivo assays. Their major drawback is the inherent variability with its practical implications. We quantified the variability of in vivo potency release assays for whole-cell pertussis, inactivated polio and meningococcal B (MenB) vaccines which showed large CV (Coefficient of Variation) ranging from 34% to 125%. As inheren...
Source: Vaccine - August 1, 2023 Category: Allergy & Immunology Authors: Cerissa van Walstijn Stefan Verweij Rory Care Peter Rigsby Eli-Boaz Clapper Kevin Markey Rob J Vandebriel Paul Stickings Marcel H N Hoefnagel Source Type: research

Association of vaccine stockout with immunisation coverage in low-income and middle-income countries: a retrospective cohort study
Conclusion Our findings show that the incidence of vaccine stockout events is associated with the decreased immunisation coverages for children in low-income and middle-income countries. However, we did not observe a statistically significant association between the increasing frequency of vaccine stockout and infant and under 5 mortality rates. (Source: BMJ Open)
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Lee, D., Lavayen, M. C., Kim, T. T., Legins, K., Seidel, M. Tags: Open access, Public health Source Type: research