TWiV 1105: All the T and B in China
TWiV reviews influenza H5N1 in North American cows and in birds throughout New York City, polio health emergency extended, ChatGPT to control vaccine hesitancy, increasing viral hepatitis worldwide, dengue public health alert in Puerto Rico, cherry trees drowning in Washington DC, death of iron lung Paul, origin and dispersal history of hepatitis B virus in Eastern Eurasia, and antibody-independent protection against heterologous SARS-CoV-2 challenge. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links fo...
Source: This Week in Virology - MP3 Edition - April 14, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1093: Reservoir bats and jumbo phage
TWiV discusses effectiveness of this season’s flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv...
Source: This Week in Virology - MP3 Edition - March 3, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1065: Cat coronavirus gains function in Cyprus
TWiV reviews ban on gain-of-function research by the House, chronic wasting disease in Tennessee deer, nOPV2 causing paralysis in children, and an outbreak of feline infectious peritonitis in Cyprus caused by a new recombinant coronavirus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Di...
Source: This Week in Virology - MP3 Edition - November 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1061: Seasonal COVID and a niche for cervical cancer
TWiV reveals a prediction of the expected endemic seasonality of COVID-19, based on circulation of human coronaviruses, and ecological clearance of vaccine-targeted human papillomaviruses and an increase in circulation of non-targeted virus types. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommi...
Source: This Week in Virology - MP3 Edition - November 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1041: Novel oral polio vaccine? with Raul Andino and Kostya Chumakov
Vincent speaks with Raul and Kostya about the development of novel oral polio vaccine from the Sabin type 2 strain, its deployment in over 600 million children, and whether it can lead to eradication of poliomyelitis. Host: Vincent Racaniello Guests: Raul Andino and Kostya Chumakov Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Engineering OPV (Cell Host Microbe) Poliopolis (Lancet) nOPV2 (Polioeradication.org) Timestamps by Jolene. T...
Source: This Week in Virology - MP3 Edition - September 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1026: Debunking RFK Jr. ’s vaccine funk with Dan Wilson
Dan Wilson returns to TWiV to debunk vaccine misinformation by RFK Jr. during his recent appearance on the Joe Rogan Experience. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Joe Rogan’s worst misinformation yet, with RFK Jr. (YouTube) Every first vaccine has been tested in placebo-controlled trials before going to market. Polio Measles HPV COVID-19 HepB Haemophilus influenzae B Pertussis Diphtheria Tetanu...
Source: This Week in Virology - MP3 Edition - July 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1022: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-1...
Source: This Week in Virology - MP3 Edition - July 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1016: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses surveillance to track progress toward poliomyelitis eradication, genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3, evaluation of Oseltamivir used to prevent hospitalization in outpatients with Influenza, viral emissions into the air and environment after SARS-CoV-2 human challenge, has COVID-19 threatened routine childhood vaccination, successful treatment of persistent symptomatic COVID-19 infection with extended duration Nirmatrelvir/Ritonavir, anemia as a risk factor for disease progression in patients admitted for COVID-19, impact of...
Source: This Week in Virology - MP3 Edition - June 17, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1001: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses an update on vaccine-derived poliovirus outbreaks, how the dream of wiping out polio might need a rethink, risk of death in patients hospitalized for COVID-19 vs seasonal Influenza in fall-winter, French Mpox cluster includes fully vaccinated patients, two individuals with potential Mpox virus reinfection, epidemiologic and clinical features of Mpox-associated deaths, FDA authorizes changes to simplify use of bivalent mRNA COVID-19 vaccines, SARS-CoV-2 during Omicron variant predominance among infants born to people with SARS-CoV-2, severe maternal morbidity and mortalit...
Source: This Week in Virology - MP3 Edition - April 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 995: Viral origin stories
TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid. Click arrow to play Download TWiV 995 (74 MB .mp3, 123 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Register for ASV 2023 •MicrobeTV Discord Server • More evidence for SARS-CoV-2 s...
Source: This Week in Virology - MP3 Edition - March 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 994: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the detection of circulating vaccine-derived poliovirus type 2 in Burundi and the Democratic Republic of the Congo, the novel oral polio vaccine type 2 story, prior COVID-19 infection associated with increased risk of newly diagnosed erectile dysfunction, adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection, correlates of protection against COVID-19 infection and intensity of symptomatic disease in vaccinated individuals exposed to SARS-CoV-2 in households in Israel, effectiveness of Nirmatrelvir–Ritonavir in preventing hospital ...
Source: This Week in Virology - MP3 Edition - March 25, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 979: Flushing out the viroids
TWiV gives an update on poliovirus in wastewater, and reveals a vast world of viroids that infect a wide range of host species in diverse ecosystems. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Nick Muzyczka passes •CDC planning wastewater testing for polio (CDC) •Wastewater testing for poliovirus (MMWR) •NY state poliovirus wastewater surveillance (NYSDOH) •CDC wa...
Source: This Week in Virology - MP3 Edition - January 29, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 964: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster, efficacy of antiviral agents against omicron subvariants BQ.1.1 and XBB, incide...
Source: This Week in Virology - MP3 Edition - December 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 952: Jake Scott put the ID in COVID-19
Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts: Vincent Racaniello, Alan Dove, Rich Condit,  and Kathy Spindler Guest: Jake Scott Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Omicron variant reproduction ex vivo (Nature) Clinical outcomes with Omicron (Nat Med) Low neutralizing antibodies i...
Source: This Week in Virology - MP3 Edition - November 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 952: Jake Scott put the ID in COVID-19
Infectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts: Vincent Racaniello, Alan Dove, Rich Condit,  and Kathy Spindler Guest: Jake Scott Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron variant reproduction ex vivo (Nature) Clinical outcomes with Omicron (Nat Med) Low neutralizing antibodies induced by bivalent booster (NEJM) Antibody responses to bivalent booster (bioRxiV...
Source: This Week in Virology - MP3 Edition - November 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts