Diagnosing Multiple Myeloma and Related Disorders
Vet Clin North Am Small Anim Pract. 2022 Oct 18:S0195-5616(22)00096-1. doi: 10.1016/j.cvsm.2022.07.009. Online ahead of print.ABSTRACTThis review provides current information on myeloma-related disorders, a group of plasma cell or immunoglobulin (Ig) secreting neoplasms including multiple myeloma, extramedullary plasmacytoma (both cutaneous and noncutaneous variants), solitary osseous plasmacytoma, Waldenstr├Âm macroglobulinemia/lymphoplasmacytic lymphoma, Ig-secretory B-cell lymphoma, plasma cell leukemia, and monoclonal gammopathy of undetermined significance. The diagnostic procedures commonly used to characterize myelo...
Source: Clinical Lymphoma and Myeloma - October 21, 2022 Category: Cancer & Oncology Authors: A Russell Moore Source Type: research

Diagnosing Multiple Myeloma and Related Disorders
This review provides current information on myeloma-related disorders, a group of plasma cell or immunoglobulin (Ig) secreting neoplasms including multiple myeloma, extramedullary plasmacytoma (both cutaneous and noncutaneous variants), solitary osseous plasmacytoma, Waldenstr ├Âm macroglobulinemia/lymphoplasmacytic lymphoma, Ig-secretory B-cell lymphoma, plasma cell leukemia, and monoclonal gammopathy of undetermined significance. The diagnostic procedures commonly used to characterize myeloma-related disorders, including cytopathology, histopathology, polymerase chain r eaction for antigen receptor rearrangement, flow cy...
Source: Veterinary Clinics of North America: Small Animal Practice - October 18, 2022 Category: Veterinary Research Authors: A Russell Moore Source Type: research

A Case Series of Aggressive Orbital Plasmacytomas
Discussion It is important to pe rform systemic evaluation and appropriate treatment immediately once the diagnosis has been established. This case series aimed to increase awareness of orbital plasmacytoma existence and consider it as one of the differential diagnosis in orbital tumor. (Source: Ocular Oncology and Pathology)
Source: Ocular Oncology and Pathology - October 12, 2022 Category: Opthalmology Source Type: research

Nodular hepatic lesion mimicking gallbladder carcinoma in myeloma
For nodular hepatic lesion mimicking gallbladder carcinoma without fluorodeoxyglucose intake, ultrasonography can be useful for rare differential diagnosis and early detection of extramedullary plasmacytoma. AbstractAn 81-year-old man was diagnosed with nodular hepatic lesion of extramedullary plasmacytoma with the absence of FDG uptake. Doppler ultrasonography showed pulsations and abundant blood flow signals within the tumor. The blood flow was temporally reduced after daratumumab-based induction therapy; however, the tumor rapidly re-expanded with blood reflow. (Source: Clinical Case Reports)
Source: Clinical Case Reports - October 11, 2022 Category: General Medicine Authors: Keiko Takatsuka, Masanori Matsumoto, Teruhito Takakuwa Tags: CASE IMAGE Source Type: research

Daratumumab plus lenalidomide and dexamethasone for relapsed POEMS syndrome with bone plasmacytoma harboring 17p deletion
This report may broaden the application of Dara-Rd for POEMS syndrome.PMID:36202948 | DOI:10.1007/s12185-022-03459-w (Source: International Journal of Hematology)
Source: International Journal of Hematology - October 6, 2022 Category: Hematology Authors: Takashi Oyama Kazuki Taoka Akira Chiba Yosuke Masamoto Masako Ikemura Akira Honda Hiroaki Maki Mineo Kurokawa Source Type: research

Daratumumab plus lenalidomide and dexamethasone for relapsed POEMS syndrome with bone plasmacytoma harboring 17p deletion
This report may broaden the application of Dara-Rd for POEMS syndrome.PMID:36202948 | DOI:10.1007/s12185-022-03459-w (Source: International Journal of Hematology)
Source: International Journal of Hematology - October 6, 2022 Category: Hematology Authors: Takashi Oyama Kazuki Taoka Akira Chiba Yosuke Masamoto Masako Ikemura Akira Honda Hiroaki Maki Mineo Kurokawa Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Mol Biol Cell - October 4, 2022 Category: Molecular Biology Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Cellular and Molecular Biology Letters - October 4, 2022 Category: Biochemistry Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Cancer Control - October 4, 2022 Category: Cancer & Oncology Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Mol Biol Cell - October 4, 2022 Category: Molecular Biology Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Cellular and Molecular Biology Letters - October 4, 2022 Category: Biochemistry Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Cellular and Molecular Biology Letters - October 4, 2022 Category: Biochemistry Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

lncRNA PVT1: a novel oncogene in multiple cancers
Cell Mol Biol Lett. 2022 Oct 4;27(1):84. doi: 10.1186/s11658-022-00385-x.ABSTRACTLong noncoding RNAs are involved in epigenetic gene modification, including binding to the chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in gene expression regulation, as well as acting as microRNA sponges to control messenger RNA levels in post-transcriptional regulation. An increasing number of studies have found that long noncoding RNA plasmacytoma variant translocation 1 (PVT1) plays an important role in cancer development. In this review of a large number of studies on PVT1, we found that PVT1 is ...
Source: Cellular and Molecular Biology Letters - October 4, 2022 Category: Biochemistry Authors: Ruiming Li Xia Wang Chunming Zhu Kefeng Wang Source Type: research

Neuroendocrine Tumor of Tailgut Cyst with Unexpected Metastases
AbstractNeuroendocrine tumors (NETs) originate from the neuroendocrine cells, which are found in various organs. NETs occur frequently in the gastrointestinal tract. NETs arising from tailgut cysts are uncommon. We herein report an interesting case of metastatic tailgut cyst NET, which was firstly diagnosed as plasmacytoma. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - October 1, 2022 Category: Nuclear Medicine Source Type: research

Non-secretory multiple myeloma expressed as multiple extramedullary plasmacytoma with an endobronchial lesion mimicking metastatic cancer: A case report
CONCLUSION: We present a rare case of non-secretory MM with multiple extramedullary plasmacytoma with an endobronchial lesion.PMID:36158506 | PMC:PMC9372843 | DOI:10.12998/wjcc.v10.i22.7899 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - September 26, 2022 Category: Cancer & Oncology Authors: Seul Bi Lee Chi Young Park Hee Jeong Lee Ran Hong Woo Shin Kim Sang-Gon Park Source Type: research