Strengthen and consolidate: A case of screw augmentation for solitary plasmacytoma of cervical spine
Asian J Surg. 2023 Aug 1:S1015-9584(23)01006-0. doi: 10.1016/j.asjsur.2023.07.029. Online ahead of print.NO ABSTRACTPMID:37537062 | DOI:10.1016/j.asjsur.2023.07.029 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - August 3, 2023 Category: Surgery Authors: Xianwei Yan Zelin Zhou Jianchao Cui Xiaobing Jiang Source Type: research
Strengthen and consolidate: A case of screw augmentation for solitary plasmacytoma of cervical spine
Asian J Surg. 2023 Aug 1:S1015-9584(23)01006-0. doi: 10.1016/j.asjsur.2023.07.029. Online ahead of print.NO ABSTRACTPMID:37537062 | DOI:10.1016/j.asjsur.2023.07.029 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - August 3, 2023 Category: Surgery Authors: Xianwei Yan Zelin Zhou Jianchao Cui Xiaobing Jiang Source Type: research
Paraskeletal plasmacytoma presenting as a chest wall mass
Monaldi Arch Chest Dis. 2023 Jul 28. doi: 10.4081/monaldi.2023.2637. Online ahead of print.ABSTRACTExtramedullary involvement in multiple myeloma is uncommon. It can present as a plasma cell mass in the soft tissue surrounding the bony structures through direct extension or in various other organs via hematogenous spread. Here, we report a case of paraskeletal plasmacytoma that manifested as a chest wall mass in a 60-year-old man.PMID:37522859 | DOI:10.4081/monaldi.2023.2637 (Source: Monaldi Archives for Chest Disease)
Source: Monaldi Archives for Chest Disease - July 31, 2023 Category: Respiratory Medicine Authors: Sonali Mallik Ananda Datta Debahuti Mohapatra Source Type: research
< em > PVT1 < /em > interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
Haematologica. 2023 Jul 27. doi: 10.3324/haematol.2023.282965. Online ahead of print.ABSTRACTMultiple myeloma is a heterogeneous haematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2. Interestingly, the recruitment of PRC2 lacks sequence specificity and, to date, the molecular mechanisms that define which genomic locat...
Source: Haematologica - July 27, 2023 Category: Hematology Authors: Patrick Nylund Berta Garrido-Zabala Alba Atienza P árraga Louella Vasquez Paul Theodor Pyl George Mickhael Harinck Anqi Ma Jian Jin Fredrik Öberg Antonia Kalushkova Helena Jernberg Wiklund Source Type: research
< em > PVT1 < /em > interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
Haematologica. 2023 Jul 27. doi: 10.3324/haematol.2023.282965. Online ahead of print.ABSTRACTMultiple myeloma is a heterogeneous haematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2. Interestingly, the recruitment of PRC2 lacks sequence specificity and, to date, the molecular mechanisms that define which genomic locat...
Source: Haematologica - July 27, 2023 Category: Hematology Authors: Patrick Nylund Berta Garrido-Zabala Alba Atienza P árraga Louella Vasquez Paul Theodor Pyl George Mickhael Harinck Anqi Ma Jian Jin Fredrik Öberg Antonia Kalushkova Helena Jernberg Wiklund Source Type: research
< em > PVT1 < /em > interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
Haematologica. 2023 Jul 27. doi: 10.3324/haematol.2023.282965. Online ahead of print.ABSTRACTMultiple myeloma is a heterogeneous haematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2. Interestingly, the recruitment of PRC2 lacks sequence specificity and, to date, the molecular mechanisms that define which genomic locat...
Source: Haematologica - July 27, 2023 Category: Hematology Authors: Patrick Nylund Berta Garrido-Zabala Alba Atienza P árraga Louella Vasquez Paul Theodor Pyl George Mickhael Harinck Anqi Ma Jian Jin Fredrik Öberg Antonia Kalushkova Helena Jernberg Wiklund Source Type: research
< em > PVT1 < /em > interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
Haematologica. 2023 Jul 27. doi: 10.3324/haematol.2023.282965. Online ahead of print.ABSTRACTMultiple myeloma is a heterogeneous haematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A common feature among patients with poor prognosis is the increased activity of the epigenetic silencer EZH2, which is the catalytic subunit of the PRC2. Interestingly, the recruitment of PRC2 lacks sequence specificity and, to date, the molecular mechanisms that define which genomic locat...
Source: Haematologica - July 27, 2023 Category: Hematology Authors: Patrick Nylund Berta Garrido-Zabala Alba Atienza P árraga Louella Vasquez Paul Theodor Pyl George Mickhael Harinck Anqi Ma Jian Jin Fredrik Öberg Antonia Kalushkova Helena Jernberg Wiklund Source Type: research
Solitary endobronchial plasmacytoma —a rare differential of an endobronchial mass
AbstractDiagnostic dilemma, owing to the inconclusiveness of biopsy results, often leaves us with limited options to offer to the patients upfront, amongst the various armamentarium available. We hereby report a rare case of extramedullary plasmacytoma, whose diagnosis was established only on the final histopathology report with the aid of immunohistochemistry. A 50-year-old gentleman presented to our outpatient setup with computed tomography suggestive of a well-defined endobronchial mass occupying the left lower lobe bronchus. However, bronchoscopy and computed tomography –guided biopsies were inconclusive. After a rou...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - July 21, 2023 Category: Cardiovascular & Thoracic Surgery Source Type: research
Screening and validation of plasma cell-derived, purinergic, and calcium signalling-related genetic signature to predict prognosis and PD-L1/PD-1 blockade responses in lung adenocarcinoma
CONCLUSION: The immune-related prognostic model based on P2RX1 and PCP4 is conducive to predicting the therapeutic response of PD-L1/PD-1 blockade and clinical outcomes of LUAD.PMID:37468608 | DOI:10.1007/s00432-023-05153-8 (Source: Cell Research)
Source: Cell Research - July 19, 2023 Category: Cytology Authors: Junfeng Huang Xingyu Fan Bingqi Hu Liwen Chen Source Type: research
Screening and validation of plasma cell-derived, purinergic, and calcium signalling-related genetic signature to predict prognosis and PD-L1/PD-1 blockade responses in lung adenocarcinoma
CONCLUSION: The immune-related prognostic model based on P2RX1 and PCP4 is conducive to predicting the therapeutic response of PD-L1/PD-1 blockade and clinical outcomes of LUAD.PMID:37468608 | DOI:10.1007/s00432-023-05153-8 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - July 19, 2023 Category: Cancer & Oncology Authors: Junfeng Huang Xingyu Fan Bingqi Hu Liwen Chen Source Type: research
