BCMA Directed Bispecific Antibody Induced Tumor Flare in Multiple Myeloma
A 53-year-old man with relapsed multiple myeloma presented with bilateral upper limb sensorimotor symptoms caused by an enlarging cervical spine (C3) tumoral lesion. His prior treatments included spinal surgery and radiotherapy (RT) 11 years earlier for solitary plasmacytoma, daratumumab bortezomib lenalidomide dexamethasone followed by high dose melphalan and autologous stem-cell transplantation and daratumumab + lenalidomide maintenance as first line therapy for systemic myeloma 4 years before current presentation. (Source: Clinical Lymphoma, Myeloma and Leukemia)
Source: Clinical Lymphoma, Myeloma and Leukemia - March 16, 2024 Category: Hematology Authors: Chandramouli Nagarajan, Martin Wong Eu Jo, Thomas G Martin Tags: Letter to the Editor Source Type: research
Combined endoscopic transorbital and transnasal approach for the management of a solitary plasmacytoma of the sphenoid bone: A case report and literature review
CONCLUSION: Surgical resection and radiotherapy may achieve remission of these lesions; however, recurrence rates remain high despite any treatment modality. Patients with this condition must be followed up with a multidisciplinary team due to the high risk of multiple myeloma progression.PMID:38468666 | PMC:PMC10927175 | DOI:10.25259/SNI_915_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Omar R Ortega-Ruiz Jorge Armando Lara Olivas Marcos V Sangrador-Deitos Ricardo Marian Maga ña Jose Augusto Ruiz Gurria Juan Luis Gomez Amador Source Type: research
