Solitary Extraosseous Plasmacytoma of Submandibular Gland – Report of a Rare Case
Conclusions: Extraosseous plasmacytoma of the submandibular region is very rare but radiosensitive tumor. Multiple myeloma must be ruled out prior to start of any treatment. Long term follow ups are required to comment on disease progression, dissemination, or recurrence. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 27, 2023 Category: ENT & OMF Source Type: research
LncRNA PVT1 as a novel biomarker for diabetes-related complications
CONCLUSION: PVT1 regulates the occurrence and progression of diabetes-related diseases. Collectively, PVT1 has the potential to be a useful diagnostic and therapeutic target for diabetes and its consequences.PMID:36809958 | DOI:10.2174/0929867330666230210103447 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - February 22, 2023 Category: Chemistry Authors: Xinyan Qiu Jinlan Chen Jingjie Yang Jiahui Hu Fan Peng Chengfu Yuan Source Type: research
LncRNA PVT1 as a novel biomarker for diabetes-related complications
CONCLUSION: PVT1 regulates the occurrence and progression of diabetes-related diseases. Collectively, PVT1 has the potential to be a useful diagnostic and therapeutic target for diabetes and its consequences.PMID:36809958 | DOI:10.2174/0929867330666230210103447 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - February 22, 2023 Category: Chemistry Authors: Xinyan Qiu Jinlan Chen Jingjie Yang Jiahui Hu Fan Peng Chengfu Yuan Source Type: research
Multiple myeloma with plasmacytoma of the clivus bone presenting with multiple cranial nerve III, IV, and VI palsy: A diagnostic dilemma
AbstractCentral nervous system (CNS) manifestation with cranial nerve palsy in multiple myeloma (MM) is a rare manifestation. Plasmacytoma originates from the bones of the skull base in 3% patients with MM but rarely develops from the soft tissues of the nasal cavity and paranasal sinuses. Here, we present a case of 68-year-old male patient with multiple myeloma, clivus bone plasmacytoma, and cavernous sinus syndrome. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 13, 2023 Category: General Medicine Authors: Chiranjiwi Prasad Shah,
Rajan Chamlagain,
Sangam Shah,
Subodh Paudel,
Sanjit Kumar Sah,
Bipin Koirala,
Kamal Pandit,
Sanjeeta Sitaula,
Anjan Shrestha Tags: CASE REPORT Source Type: research
PVT1/miR-16/CCND1 axis regulates gastric cancer progression
In conclusion, PVT1 promoted CCND1 expression by negatively regulating miR-16 expression to enhance the viability, invasion and cell cycle progression of GC cells.PMID:36760720 | PMC:PMC9896163 | DOI:10.1515/med-2022-0550 (Source: Cancer Control)
Source: Cancer Control - February 10, 2023 Category: Cancer & Oncology Authors: Haidong Lv Dixia Zhou Guoqing Liu Source Type: research
High prevalence of Wilms tumor 1 expression in multiple myeloma and plasmacytoma: A cohort of 142 Asian patients' samples
This study confirms the high prevalence of WT1 expression in an Asian cohort of MM, encouraging the development of immunotherapy targeting WT1 in MM patients, particularly in those with extramedullary plasmacytoma or relapsed disease.PMID:36760714 | PMC:PMC9902379 | DOI:10.3389/pore.2023.1610844 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - February 10, 2023 Category: Pathology Authors: Ployploen Phikulsod Sanya Sukpanichnant Chutima Kunacheewa Thaweesak Chieochansin Mutita Junking Pa-Thai Yenchitsomanus Source Type: research
High prevalence of Wilms tumor 1 expression in multiple myeloma and plasmacytoma: A cohort of 142 Asian patients' samples
This study confirms the high prevalence of WT1 expression in an Asian cohort of MM, encouraging the development of immunotherapy targeting WT1 in MM patients, particularly in those with extramedullary plasmacytoma or relapsed disease.PMID:36760714 | PMC:PMC9902379 | DOI:10.3389/pore.2023.1610844 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - February 10, 2023 Category: Pathology Authors: Ployploen Phikulsod Sanya Sukpanichnant Chutima Kunacheewa Thaweesak Chieochansin Mutita Junking Pa-Thai Yenchitsomanus Source Type: research
High prevalence of Wilms tumor 1 expression in multiple myeloma and plasmacytoma: A cohort of 142 Asian patients' samples
This study confirms the high prevalence of WT1 expression in an Asian cohort of MM, encouraging the development of immunotherapy targeting WT1 in MM patients, particularly in those with extramedullary plasmacytoma or relapsed disease.PMID:36760714 | PMC:PMC9902379 | DOI:10.3389/pore.2023.1610844 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - February 10, 2023 Category: Pathology Authors: Ployploen Phikulsod Sanya Sukpanichnant Chutima Kunacheewa Thaweesak Chieochansin Mutita Junking Pa-Thai Yenchitsomanus Source Type: research
Extramedullary relapse of Immunoglobulin A-kappa myeloma manifesting as plasmacytoma of the pleura without bone marrow involvement and following autologous bone marrow transplant: a case report
ConclusionPhysicians should be aware of various presentations of multiple myeloma relapse, especially in autologous stem cell transplantation patients. Atypical and unique presentations such as the pleural involvement warrant further reporting of evidence to provide early management and treatment options. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 10, 2023 Category: General Medicine Source Type: research
Rare Pattern of Myelodysplastic Syndrome (MDS) with Serum Monoclonal Immunoglobulin: Case Report
CONCLUSION: The combination of plasma cell disease and myeloid malignancy may increase mortality. This is uncommon and may be easily misdiagnosed if not detected early. When a myeloid neoplasm tests positive for MDS and serum M protein, clinicians should evaluate for other plasma cell disease.PMID:36735715 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 3, 2023 Category: Complementary Medicine Authors: Yating Lin Jun He Fan Li Xuezhong Gu Source Type: research
Isolated relapse of plasma cell leukemia in the central nervous systems: a case report and literature review
Int J Hematol. 2023 Feb 3. doi: 10.1007/s12185-023-03545-7. Online ahead of print.ABSTRACTPlasma cell leukemia is a rare yet aggressive form of multiple myeloma characterized by high levels of plasma cells circulating in the peripheral blood. We recently experienced a case of plasma cell leukemia that had been in stringent complete remission for nine years after autologous stem cell transplantations with subsequent courses of lenalidomide maintenance therapy, and then relapsed as an extramedullary plasmacytoma in the central nervous system. Assessment of the bone marrow did not prove proliferation of plasma cells at relaps...
Source: International Journal of Hematology - February 3, 2023 Category: Hematology Authors: Takafumi Obo Ken Morita Yutaro Sumida Kumi Nakazaki-Watadani Masako Ikemura Koichiro Yasaka Osamu Abe Hirokazu Takami Shunsaku Takayanagi Shota Tanaka Hiroaki Maki Yosuke Masamoto Akiyoshi Miwa Mineo Kurokawa Source Type: research
Rare Pattern of Myelodysplastic Syndrome (MDS) with Serum Monoclonal Immunoglobulin: Case Report
CONCLUSION: The combination of plasma cell disease and myeloid malignancy may increase mortality. This is uncommon and may be easily misdiagnosed if not detected early. When a myeloid neoplasm tests positive for MDS and serum M protein, clinicians should evaluate for other plasma cell disease.PMID:36735715 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 3, 2023 Category: Complementary Medicine Authors: Yating Lin Jun He Fan Li Xuezhong Gu Source Type: research
Isolated relapse of plasma cell leukemia in the central nervous systems: a case report and literature review
Int J Hematol. 2023 Feb 3. doi: 10.1007/s12185-023-03545-7. Online ahead of print.ABSTRACTPlasma cell leukemia is a rare yet aggressive form of multiple myeloma characterized by high levels of plasma cells circulating in the peripheral blood. We recently experienced a case of plasma cell leukemia that had been in stringent complete remission for nine years after autologous stem cell transplantations with subsequent courses of lenalidomide maintenance therapy, and then relapsed as an extramedullary plasmacytoma in the central nervous system. Assessment of the bone marrow did not prove proliferation of plasma cells at relaps...
Source: International Journal of Hematology - February 3, 2023 Category: Hematology Authors: Takafumi Obo Ken Morita Yutaro Sumida Kumi Nakazaki-Watadani Masako Ikemura Koichiro Yasaka Osamu Abe Hirokazu Takami Shunsaku Takayanagi Shota Tanaka Hiroaki Maki Yosuke Masamoto Akiyoshi Miwa Mineo Kurokawa Source Type: research
Rare Pattern of Myelodysplastic Syndrome (MDS) with Serum Monoclonal Immunoglobulin: Case Report
CONCLUSION: The combination of plasma cell disease and myeloid malignancy may increase mortality. This is uncommon and may be easily misdiagnosed if not detected early. When a myeloid neoplasm tests positive for MDS and serum M protein, clinicians should evaluate for other plasma cell disease.PMID:36735715 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 3, 2023 Category: Complementary Medicine Authors: Yating Lin Jun He Fan Li Xuezhong Gu Source Type: research
Rare Pattern of Myelodysplastic Syndrome (MDS) with Serum Monoclonal Immunoglobulin: Case Report
CONCLUSION: The combination of plasma cell disease and myeloid malignancy may increase mortality. This is uncommon and may be easily misdiagnosed if not detected early. When a myeloid neoplasm tests positive for MDS and serum M protein, clinicians should evaluate for other plasma cell disease.PMID:36735715 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 3, 2023 Category: Complementary Medicine Authors: Yating Lin Jun He Fan Li Xuezhong Gu Source Type: research
