Increased maximal oxygen uptake after sprint-interval training is mediated by central hemodynamic factors as determined by right heart catheterization
This study investigated the importance of maximal cardiac output (Qmax ) in relation to VO2max improvements following SIT and the relative importance of the hypervolemic response on Qmax and VO2max . We also investigated if systemic O2 extraction increased with SIT as has been previously suggested. Healthy men and women (n = 9) performed 6 weeks of SIT. State-of-the-art measurements: right heart catheterization, carbon monoxide rebreathing and respiratory gas exchange analysis were used to assess Qmax , arterial O2 content (ca O2 ), mixed venous O2 content (cv O2 ), blood volume (BV) and VO2max before and after the interve...
Source: The Journal of Physiology - April 18, 2023 Category: Physiology Authors: Mirko Mandi ć Lisa M J Eriksson Michael Melin Viktoria Skott Patrik Sundblad Thomas Gustafsson Eric Rullman Source Type: research
Increased maximal oxygen uptake after sprint-interval training is mediated by central hemodynamic factors as determined by right heart catheterization
This study investigated the importance of maximal cardiac output (Qmax ) in relation to VO2max improvements following SIT and the relative importance of the hypervolemic response on Qmax and VO2max . We also investigated if systemic O2 extraction increased with SIT as has been previously suggested. Healthy men and women (n = 9) performed 6 weeks of SIT. State-of-the-art measurements: right heart catheterization, carbon monoxide rebreathing and respiratory gas exchange analysis were used to assess Qmax , arterial O2 content (ca O2 ), mixed venous O2 content (cv O2 ), blood volume (BV) and VO2max before and after the interve...
Source: The Journal of Physiology - April 18, 2023 Category: Physiology Authors: Mirko Mandi ć Lisa M J Eriksson Michael Melin Viktoria Skott Patrik Sundblad Thomas Gustafsson Eric Rullman Source Type: research
Increased maximal oxygen uptake after sprint-interval training is mediated by central hemodynamic factors as determined by right heart catheterization
This study investigated the importance of maximal cardiac output (Qmax ) in relation to VO2max improvements following SIT and the relative importance of the hypervolemic response on Qmax and VO2max . We also investigated if systemic O2 extraction increased with SIT as has been previously suggested. Healthy men and women (n = 9) performed 6 weeks of SIT. State-of-the-art measurements: right heart catheterization, carbon monoxide rebreathing and respiratory gas exchange analysis were used to assess Qmax , arterial O2 content (ca O2 ), mixed venous O2 content (cv O2 ), blood volume (BV) and VO2max before and after the interve...
Source: The Journal of Physiology - April 18, 2023 Category: Physiology Authors: Mirko Mandi ć Lisa M J Eriksson Michael Melin Viktoria Skott Patrik Sundblad Thomas Gustafsson Eric Rullman Source Type: research
A prospective assessment of the time required to obtain one unit of fresh whole blood by civilian phlebotomists and Army laboratory technicians (68 K)
CONCLUSIONS: We found a high first intravenous cannulation attempt success among both the civilian and Army technicians. Medians times were <5 min to obtain venipuncture and <11 min to obtain one unit. These findings provide time-based benchmarks for potential use during transfusion training among military medics.PMID:37066994 | DOI:10.1111/trf.17341 (Source: Transfusion)
Source: Transfusion - April 17, 2023 Category: Hematology Authors: Fabiola Mancha Jessica Mendez Michael D April Andrew D Fisher Ronnie Hill James Bynum Andrew P Cap Jason B Corley Steven G Schauer Source Type: research
A prospective assessment of the time required to obtain one unit of fresh whole blood by civilian phlebotomists and Army laboratory technicians (68 K)
CONCLUSIONS: We found a high first intravenous cannulation attempt success among both the civilian and Army technicians. Medians times were <5 min to obtain venipuncture and <11 min to obtain one unit. These findings provide time-based benchmarks for potential use during transfusion training among military medics.PMID:37066994 | DOI:10.1111/trf.17341 (Source: Transfusion)
Source: Transfusion - April 17, 2023 Category: Hematology Authors: Fabiola Mancha Jessica Mendez Michael D April Andrew D Fisher Ronnie Hill James Bynum Andrew P Cap Jason B Corley Steven G Schauer Source Type: research
Polycythemia vera: aspects of its current diagnosis and initial treatment
Expert Rev Hematol. 2023 Apr 4. doi: 10.1080/17474086.2023.2198698. Online ahead of print.ABSTRACTINTRODUCTION: Significant advances have been made in the diagnosis and management of patients with polycythemia vera (PV) over the past two decades, but a few important issues remain, either overlooked or controversial.AREAS COVERED: We discuss making an accurate diagnosis of PV with careful interpretation of hematocrit values, red cell count, and red cell mass when available, and bone marrow histomorphology to distinguish PV from other JAK2V617F myeloproliferative neoplasms (MPNs). We cover aspects of initial PV treatment wit...
Source: Expert Review of Hematology - April 4, 2023 Category: Hematology Authors: Richard T Silver Ghaith Abu-Zeinah Source Type: research
Cancers, Vol. 15, Pages 2103: Phase IIa Clinical Biomarker Trial of Dietary Arginine Restriction and Aspirin in Colorectal Cancer Patients
ael J. Stamos
After potentially curative treatment, colorectal cancer (CRC) patients remain at high risk for recurrence, second primary CRC, and high-risk adenomas. In combination with existing data, our previous findings provide a rationale for reducing tissue polyamines as tertiary prevention in non-metastatic CRC patients. The goal of this study was to demonstrate rectal tissue polyamine reduction in optimally treated stage I-III CRC patients after intervention with daily oral aspirin + dietary arginine restriction. A single-institution phase IIa clinical trial was conducted. Patients were treated with aspirin 325 m...
Source: Cancers - March 31, 2023 Category: Cancer & Oncology Authors: Jason A. Zell Thomas H. Taylor C. Gregory Albers Joseph C. Carmichael Christine E. McLaren Lari Wenzel Michael J. Stamos Tags: Article Source Type: research
Do different wiping techniques in phlebotomy have an effect on vessel visibility, procedural success, and phlebotomy-related complications?
CONCLUSIONS: Vertical wiping and vertical + circular wiping techniques used in the cleaning of the phlebotomy site increased the visibility of the vein compared to only circular wiping. The time spent for blood sampling was shorter in the vertical wiping and vertical + circular wiping groups.PMID:36971416 | DOI:10.1177/11297298231164181 (Source: The Journal of Vascular Access)
Source: The Journal of Vascular Access - March 27, 2023 Category: Surgery Authors: Sevda Korkut T ürkan Ülker Sevil G üler Şebnem Gürsoy Source Type: research
