Bismuth-Based Quadruple Therapy as First-Line Treatment for Clarithromycin-resistant < em > Helicobacter pylori < /em > Infection: A Prospective Randomized Comparison of 7- and 14-Day Treatment Regimens
CONCLUSIONS: : Both 7-day and 14-day BQT were effective and safe as first-line therapy for HP infections identified as resistant to clarithromycin by RT-PCR. For clarithromycin-resistant HP infections, 7-day BQT may be sufficient as first-line therapy.PMID:38712395 | DOI:10.5009/gnl230453 (Source: Gut and Liver)
Source: Gut and Liver - May 7, 2024 Category: Gastroenterology Authors: Chul-Hyun Lim Jung-Hwan Oh Source Type: research

1243 global health inequality analysis of premature mortality related to peptic ulcer disease: a systematic analysis based on global burden of disease
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Yunhao Li, Fang Jiang, Xue Li, David Bishai, Wai Keung Leung Tags: AGA Abstracts Source Type: research

655 the ppi strategy after transcatheter arterial embolization in refractory peptic ulcer bleeding patients: a randomized control study
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Xue Xiao, Xiaoze Wang, Xuefeng Luo, Jinlin Yang Tags: AGA Abstracts Source Type: research

Su1103 HIGH RATES OF INAPPROPRIATE PROTON-PUMP INHIBITOR PERSISTENCE AMONG PATIENTS WITH A HISTORY OF PEPTIC ULCER DISEASE WITHOUT ALTERNATIVE INDICATIONS: AN OVERLOOKED OPPORTUNITY FOR DEPRESCRIBING
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Jordan A. Villars, Timothy S. Anderson, Ravy K. Vajravelu Tags: AGA Abstracts Source Type: research

Sa1358 RISK OF SEVERE PEPTIC ULCER DISEASE ASSOCIATED WITH HELICOBACTER PYLORI INFECTION IN A LARGE, COMMUNITY-BASED U.S. POPULATION
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Sophie A. Merchant, Jessica Badalov, Douglas A. Corley, Dan Li Tags: AGA Abstracts Source Type: research

Tu1363 OUTCOMES OF PEPTIC ULCER DISEASE RELATED BLEEDING IN PATIENTS WITH RECENT ACUTE MYOCARDIAL INFARCTION: A U.S. PROPENSITY MATCHED COHORT STUDY
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Achintya D. Singh, Aakash Desai, Amit Bhatt, Bhavesh Shah, Douglas G. Adler Tags: AGA Abstracts Source Type: research

Tu1362 HEMORRHAGIC PEPTIC ULCER DISEASE (HPUD) OUTCOMES IN ADVANCED CHRONIC KIDNEY DISEASE AND KIDNEY TRANSPLANT (KT) RECIPIENTS: A NATIONWIDE ANALYSIS
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Mingyue He, Shaan H. Desai, Frank K. Friedenberg Tags: AGA Abstracts Source Type: research

From lab to nature: Recent advancements in the journey of gastroprotective agents from medicinal chemistry to phytotherapy
Eur J Med Chem. 2024 Apr 23;272:116436. doi: 10.1016/j.ejmech.2024.116436. Online ahead of print.ABSTRACTPeptic ulcer, affecting 10 % of the global population, results from imbalances in gastric juice pH and diminished mucosal defences. Key underlying factors are non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection, undermining mucosal resistance. Traditional treatments like proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists exhibit drawbacks such as adverse effects, relapses, and drug interactions. This review extensively explores the ethnomedicinal, synthetic and pharmacol...
Source: European Journal of Medicinal Chemistry - May 5, 2024 Category: Chemistry Authors: Susmita Yadav Anima Pandey Suraj N Mali Source Type: research

Molecular characterization and phylogenetic analysis of babA gene of Helicobacter pylori isolated from Indian patients with gastrointestinal diseases
CONCLUSION: The appearance of variants within distinct disease categories is due to local genetic variation.PMID:38703866 | DOI:10.1016/j.gene.2024.148526 (Source: Gene)
Source: Gene - May 4, 2024 Category: Genetics & Stem Cells Authors: Sarika Singh Amresh Kumar Sharma Anup Som Valentina Gehlot Shweta Mahant Prateek Sharma Kunal Das Rajashree Das Source Type: research

Molecular characterization and phylogenetic analysis of babA gene of Helicobacter pylori isolated from Indian patients with gastrointestinal diseases
CONCLUSION: The appearance of variants within distinct disease categories is due to local genetic variation.PMID:38703866 | DOI:10.1016/j.gene.2024.148526 (Source: Gene)
Source: Gene - May 4, 2024 Category: Genetics & Stem Cells Authors: Sarika Singh Amresh Kumar Sharma Anup Som Valentina Gehlot Shweta Mahant Prateek Sharma Kunal Das Rajashree Das Source Type: research

Postoperative Bowel Obstruction as a Rare Complication of an Abdominal Drain
Ann Ital Chir. 2024;95(2):132-135. doi: 10.62713/aic.3294.ABSTRACTAlthough routine intra-abdominal drain insertion following surgery represents a common practice worldwide, its utility has been questioned during the last decades. Several comparative studies have failed to document significant benefits from routine draining, and drain insertion has been correlated with various complications as well. Drain-related complications include, but are not limited, to infection, bleeding, and tissue erosion. Herein, we present the case of a 32-year-old patient with perforated peptic ulcer and purulent peritonitis, whose postoperativ...
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Iraklis Perysinakis Evangelia E Vassalou Georgios Saridakis Matthaios Triantafyllou Vasilis Christodoulou Paraskevi Triantafylla Eufrosini Papadaki Eelco De Bree Source Type: research