Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Pancreatic Cancer: Rapid Evidence Review
Am Fam Physician. 2024 Mar;109(3):245-250.ABSTRACTPancreatic cancer is relatively uncommon and carries a poor prognosis because patients often develop signs or symptoms at a late stage of illness. Patients with a family history, especially those with genetic syndromes, are at a significantly increased risk of pancreatic cancer. Modifiable risk factors include smoking, heavy alcohol use, and obesity. Although patients at increased risk should be screened, screening is not recommended for asymptomatic people at average risk. The differential diagnosis for a symptomatic patient is broad, including gastroesophageal reflux dise...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Carl Bryce Merima Bucaj Source Type: research

Comparison of Vonoprazan versus Intravenous Proton Pump Inhibitor for Prevention of High-Risk Peptic Ulcers Rebleeding after Successful Endoscopic Hemostasis: A Multicenter Randomized Noninferiority Trial
This study aims to compare the efficacy of vonoprazan versus PPI for preventing high-risk PU rebleeding after hemostasis. (Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Tanawat Geeratragool, Uayporn Kaosombatwattana, Arpapun Boonchote, Suvikrom Chatthammanat, Nutchanun Preechakawin, Jompol Srichot, Asawin Sudcharoen, Pavapol Sirisunhirun, Panotpol Termsinsuk, Manus Rugivarodom, Julajak Limsrivilai, Monthira Maneerattanap Tags: Clinical - Alimentary Tract Source Type: research

Comparison of Vonoprazan vs Intravenous Proton Pump Inhibitor for Prevention of High-Risk Peptic Ulcers Rebleeding After Successful Endoscopic Hemostasis: A Multicenter Randomized Noninferiority Trial
Oral vonoprazan is noninferior to intravenous proton pump inhibitors in preventing 30-day rebleeding in high-risk peptic ulcers after successful hemostasis with a comparable safety profile. (Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Tanawat Geeratragool, Uayporn Kaosombatwattana, Arpapun Boonchote, Suvikrom Chatthammanat, Nutchanun Preechakawin, Jompol Srichot, Asawin Sudcharoen, Pavapol Sirisunhirun, Panotpol Termsinsuk, Manus Rugivarodom, Julajak Limsrivilai, Monthira Maneerattanap Tags: Clinical - Alimentary Tract Source Type: research

Perforated peptic ulcer - a case series and an African perspective
CONCLUSION: Patients were mostly smokers, presented late to hospital and had gastric perforations. The findings of low mortality and male predominance concurred with those of other sub-Saharan African reports and were the opposite of trends in HIC.PMID:38568129 (Source: South African Journal of Surgery)
Source: South African Journal of Surgery - April 3, 2024 Category: Surgery Authors: M T Mahlefahlo O D Montwedi V O L Karusseit Source Type: research