Tu1362 HEMORRHAGIC PEPTIC ULCER DISEASE (HPUD) OUTCOMES IN ADVANCED CHRONIC KIDNEY DISEASE AND KIDNEY TRANSPLANT (KT) RECIPIENTS: A NATIONWIDE ANALYSIS
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Mingyue He, Shaan H. Desai, Frank K. Friedenberg Tags: AGA Abstracts Source Type: research

From lab to nature: Recent advancements in the journey of gastroprotective agents from medicinal chemistry to phytotherapy
Eur J Med Chem. 2024 Apr 23;272:116436. doi: 10.1016/j.ejmech.2024.116436. Online ahead of print.ABSTRACTPeptic ulcer, affecting 10 % of the global population, results from imbalances in gastric juice pH and diminished mucosal defences. Key underlying factors are non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection, undermining mucosal resistance. Traditional treatments like proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists exhibit drawbacks such as adverse effects, relapses, and drug interactions. This review extensively explores the ethnomedicinal, synthetic and pharmacol...
Source: European Journal of Medicinal Chemistry - May 5, 2024 Category: Chemistry Authors: Susmita Yadav Anima Pandey Suraj N Mali Source Type: research

From lab to nature: Recent advancements in the journey of gastroprotective agents from medicinal chemistry to phytotherapy
Eur J Med Chem. 2024 Apr 23;272:116436. doi: 10.1016/j.ejmech.2024.116436. Online ahead of print.ABSTRACTPeptic ulcer, affecting 10 % of the global population, results from imbalances in gastric juice pH and diminished mucosal defences. Key underlying factors are non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection, undermining mucosal resistance. Traditional treatments like proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists exhibit drawbacks such as adverse effects, relapses, and drug interactions. This review extensively explores the ethnomedicinal, synthetic and pharmacol...
Source: European Journal of Medicinal Chemistry - May 5, 2024 Category: Chemistry Authors: Susmita Yadav Anima Pandey Suraj N Mali Source Type: research

Molecular characterization and phylogenetic analysis of babA gene of Helicobacter pylori isolated from Indian patients with gastrointestinal diseases
CONCLUSION: The appearance of variants within distinct disease categories is due to local genetic variation.PMID:38703866 | DOI:10.1016/j.gene.2024.148526 (Source: Gene)
Source: Gene - May 4, 2024 Category: Genetics & Stem Cells Authors: Sarika Singh Amresh Kumar Sharma Anup Som Valentina Gehlot Shweta Mahant Prateek Sharma Kunal Das Rajashree Das Source Type: research

Molecular characterization and phylogenetic analysis of babA gene of Helicobacter pylori isolated from Indian patients with gastrointestinal diseases
CONCLUSION: The appearance of variants within distinct disease categories is due to local genetic variation.PMID:38703866 | DOI:10.1016/j.gene.2024.148526 (Source: Gene)
Source: Gene - May 4, 2024 Category: Genetics & Stem Cells Authors: Sarika Singh Amresh Kumar Sharma Anup Som Valentina Gehlot Shweta Mahant Prateek Sharma Kunal Das Rajashree Das Source Type: research

Postoperative Bowel Obstruction as a Rare Complication of an Abdominal Drain
Ann Ital Chir. 2024;95(2):132-135. doi: 10.62713/aic.3294.ABSTRACTAlthough routine intra-abdominal drain insertion following surgery represents a common practice worldwide, its utility has been questioned during the last decades. Several comparative studies have failed to document significant benefits from routine draining, and drain insertion has been correlated with various complications as well. Drain-related complications include, but are not limited, to infection, bleeding, and tissue erosion. Herein, we present the case of a 32-year-old patient with perforated peptic ulcer and purulent peritonitis, whose postoperativ...
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Iraklis Perysinakis Evangelia E Vassalou Georgios Saridakis Matthaios Triantafyllou Vasilis Christodoulou Paraskevi Triantafylla Eufrosini Papadaki Eelco De Bree Source Type: research