Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group
CONCLUSION: We conclude that IHC is a useful tool in the diagnosis of PV with the highest sensitivity of IgG and C3d. The combination of IgG and C3d could replace the DIF in almost all of our cases, so IHC on FFPE sections be used as an alternative method to DIF.PMID:38427745 | DOI:10.4103/ijpm.ijpm_113_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Deepika Rana Nita Khurana Shramana Mandal Bijay Laxmi Sahoo Source Type: research
Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group
CONCLUSION: We conclude that IHC is a useful tool in the diagnosis of PV with the highest sensitivity of IgG and C3d. The combination of IgG and C3d could replace the DIF in almost all of our cases, so IHC on FFPE sections be used as an alternative method to DIF.PMID:38427745 | DOI:10.4103/ijpm.ijpm_113_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - March 1, 2024 Category: Pathology Authors: Deepika Rana Nita Khurana Shramana Mandal Bijay Laxmi Sahoo Source Type: research
Disease severity and hospitalization risk factors in a cohort of Hispanic/Latino pemphigus patients: a descriptive retrospective chart review
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 29, 2024 Category: Dermatology Authors: Rebecca Leibowitz, Mason Seely, Larissa Rodriguez Holms, Danielle Mustin, Robyn Guo, Ron J. Feldman, Anne L. Marano Source Type: research
Evaluation of the Status of Patients with Autoimmune Bullous Diseases (Pemphigus and Bullous Pemphigoids) in Dermatology Clinics of Mashhad University of Medical Sciences During the COVID-19 Pandemic Using Telemedicine
Telemedicine and e-Health, Ahead of Print. (Source: Telemedicine and e-Health)
Source: Telemedicine and e-Health - February 27, 2024 Category: Information Technology Authors: Zohreh Mehri Yalda Nahidi Behrokh Ramezani Shatila Torabi Source Type: research
Efficacy of Rituximab in the Treatment of Pemphigus Vulgaris: A Meta-analysis
CONCLUSION: The results of this study suggest that Rituximab may be effective in patients with pemphigus vulgaris, which will bring light for patients and doctors. And the above conclusions need to be verified by more high-quality studies.PMID:38401108 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 24, 2024 Category: Complementary Medicine Authors: Yanxia Cai Yaqin Liu Shiyin Deng Yaqi Luo Liehua Deng Source Type: research
Efficacy of Rituximab in the Treatment of Pemphigus Vulgaris: A Meta-analysis
CONCLUSION: The results of this study suggest that Rituximab may be effective in patients with pemphigus vulgaris, which will bring light for patients and doctors. And the above conclusions need to be verified by more high-quality studies.PMID:38401108 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 24, 2024 Category: Complementary Medicine Authors: Yanxia Cai Yaqin Liu Shiyin Deng Yaqi Luo Liehua Deng Source Type: research
Efficacy of Rituximab in the Treatment of Pemphigus Vulgaris: A Meta-analysis
CONCLUSION: The results of this study suggest that Rituximab may be effective in patients with pemphigus vulgaris, which will bring light for patients and doctors. And the above conclusions need to be verified by more high-quality studies.PMID:38401108 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 24, 2024 Category: Complementary Medicine Authors: Yanxia Cai Yaqin Liu Shiyin Deng Yaqi Luo Liehua Deng Source Type: research
Efficacy of Rituximab in the Treatment of Pemphigus Vulgaris: A Meta-analysis
CONCLUSION: The results of this study suggest that Rituximab may be effective in patients with pemphigus vulgaris, which will bring light for patients and doctors. And the above conclusions need to be verified by more high-quality studies.PMID:38401108 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 24, 2024 Category: Complementary Medicine Authors: Yanxia Cai Yaqin Liu Shiyin Deng Yaqi Luo Liehua Deng Source Type: research
Efficacy of Rituximab in the Treatment of Pemphigus Vulgaris: A Meta-analysis
CONCLUSION: The results of this study suggest that Rituximab may be effective in patients with pemphigus vulgaris, which will bring light for patients and doctors. And the above conclusions need to be verified by more high-quality studies.PMID:38401108 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - February 24, 2024 Category: Complementary Medicine Authors: Yanxia Cai Yaqin Liu Shiyin Deng Yaqi Luo Liehua Deng Source Type: research
Truth-telling in dermatology: historical perspective and modern challenges to breaking bad news
Breaking bad news is rarely discussed in dermatology. However, dermatologists often provide upsetting diagnoses of conditions ranging from skin cancer to pemphigus vulgaris. Centuries ago, doctors did not disclose upsetting diagnoses, believing patients might die of grief. Now, patients check online health portals that reveal their diagnoses instantly. This has altered how dermatologists break bad news. We provide a historical and ethics-based perspective on the evolution of disclosure and its effects in dermatology (Fig 1). (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 21, 2024 Category: Dermatology Authors: Emily R. Gordon, Megan H. Trager, Oluwaseyi Adeuyan, Caroline Chen, Brigit A. Lapolla, Celine M. Schreidah, Cori Salvit, Douglas J. Koo, Larisa J. Geskin Tags: Humanities Source Type: research
Putative pemphigus-like reaction to oral fluralaner in a dog
Vet Dermatol. 2024 Feb 14. doi: 10.1111/vde.13243. Online ahead of print.ABSTRACTA 9-month-old mixed-breed dog developed generalised pustular dermatitis, accompanied by lethargy and hyperthermia, 7 days after oral fluralaner administration. Dermatopathological and microbiological evaluations were consistent with a pustular acantholytic dermatitis. A 4-month course of immunosuppressive therapy resulted in complete remission of lesions, which did not recur after therapy was withdrawn.PMID:38356040 | DOI:10.1111/vde.13243 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - February 15, 2024 Category: Veterinary Research Authors: Annabel Dalmau Laura Ordeix Source Type: research
From neglect to spotlight: the underappreciated role of B cells in cutaneous inflammatory diseases
The skin, covering our entire body as its largest organ, manifests enormous complexities and a profound interplay of systemic and local responses. In this heterogeneous domain, B cells were considered strangers. Yet, recent studies have highlighted their existence in the skin and their distinct role in modulating cutaneous immunity across various immune contexts. Accumulating evidence is progressively shedding light on the significance of B cells in maintaining skin health and in skin disorders. Herein, we integrate current insights on the systemic and local contributions of B cells in three prevalent inflammatory skin con...
Source: Frontiers in Immunology - February 15, 2024 Category: Allergy & Immunology Source Type: research
Exacerbation of oral pemphigus vulgaris after COVID ‐19 vaccine: Coincidence or potential adverse effect?
(Source: Oral Surgery)
Source: Oral Surgery - February 6, 2024 Category: ENT & OMF Authors: Lucas Alves da Mota Santana,
Lysandro Pinto Borges,
Marina dos Santos Barreto,
Ronaldy Santana Santos,
Deise Maria Rego Rodrigues Silva,
Eloia Emanuelly Dias Silva,
Breno Ferreira Barbosa,
Lara Góis Floresta,
Lucas Morais Rodrigues Melo,
Carl Tags: LETTER TO THE EDITOR Source Type: research
A Global View of Pemphigus: Geographical Variations
AbstractPemphigus, an autoimmune intraepidermal bullous disease group with roughly eight distinct forms, includes pemphigus vulgaris (PV) and pemphigus foliaceus (PF) as its predominant global forms. Despite the increased utilization of global health records and reporting systems, epidemiological data remain limited and poorly categorized. Therefore, this study aimed to conduct a review to track, identify, and characterize cases of PV and PF published and categorized worldwide. A research question was formulated; studies were selected based on the inclusion criteria; and data from these publications were systematically col...
Source: Clinical Reviews in Allergy and Immunology - January 30, 2024 Category: Allergy & Immunology Source Type: research
Sustained Remission With Rituximab in Patients With Pemphigus
This cohort study using follow-up data from the Ritux 3 randomized clinical trial examines the association of rituximab treatment with long-term complete remission without corticosteroid therapy when used as first-line treatment for patients with pemphigus. (Source: JAMA Dermatology)
Source: JAMA Dermatology - January 24, 2024 Category: Dermatology Source Type: research
