Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312 (Source: Journal of Immunology)
Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research
Pemphigus vulgaris in a neonate born to a mother with pemphigus vulgaris: A case report
We reported the case of a 28-year-old Gravida 2 Parity 2 Living 1 who developed painful blisters and erosions in the oral cavity during third trimester of pregnancy. However, the diagnosis was delayed due to late presentation. The patient presented to our hospital at 37 weeks gestation with bullae and erosions distributed all over the body. Based on clinical evaluation and histopathology reports, she was diagnosed with PV. She delivered a child via cesarean section. The child also had similar lesions and was diagnosed with neonatal PV. Maternal PV was managed wi th prednisolone followed by azathioprine, leading to compl...
Source: Clinical Case Reports - December 19, 2023 Category: General Medicine Authors: Ayush Anand,
Praneet Awake,
Anand Bhosale,
Rajan Bindu,
Anjali Kher,
Prasad Bhanap Tags: CASE REPORT Source Type: research
Pemphigus and pemphigoid are associated with Alzheimer ’s disease in older adults: evidence from the US Nationwide inpatient sample 2016–2018
Pemphigus and pemphigoid are rare autoimmune skin disorders caused by autoantibodies against structural proteins and characterized by blistering of the skin and/or mucous membranes. Associations have been note... (Source: BMC Geriatrics)
Source: BMC Geriatrics - December 19, 2023 Category: Geriatrics Authors: Zhen Xie, Yang Gao, Lidi Tian, Yang Jiang, Hao Zhang and Yang Su Tags: Research Source Type: research
Cut-off values for IL-21 and IL-23 as biochemical markers for pemphigus vulgaris
This study aimed to compare the serum levels of IL-21 and IL-23 in patients with PV and healthy controls. This case-control study included 90 participants (45 patients and 45 controls). Serum IL-21 and IL-23 were measured using the Sandwich-ELISA method provided by Sunlong Biotech, China. The findings revealed statistically significant results for IL-21 O.D. and Conc. (p=0.012*) and highly significant results for IL-23 O.D. and Conc. (p=0.000**). Furthermore, cut-off values were established for IL-21 (O.D.=0.071 pg/mL, Conc.=6.468 pg/mL) and IL-23 (O.D.=0.141 pg/mL, Conc.=6.745 pg/mL). These results indicate a potential as...
Source: Journal of Medicine and Life - December 18, 2023 Category: General Medicine Authors: Zahra Ali Al-Hasnawi Ban Al-Drobie Source Type: research
