Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris

In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.PMID:38117802 | DOI:10.4049/jimmunol.2300312

Source: Journal of Immunology - December 20, 2023 Category: Allergy & Immunology Authors: Shumin Duan Qionghua Li Fei Wang Wenjing Kuang Yunmei Dong Dan Liu Jiongke Wang Wei Li Qianming Chen Xin Zeng Taiwen Li Source Type: research