Safety Profile of Selective Serotonin Reuptake Inhibitors in Real-World Settings: A Pharmacovigilance Study Based on FDA Adverse Event Reporting System
CONCLUSIONS AND RELEVANCE: Most of our findings are consistent with those reported previously, but some AEs were not previously identified. However, AEs attributed to SSRIs remain ambiguous, warranting further validation. Applying data-mining methods to the FAERS database can provide additional insights that can assist in appropriately utilizing SSRIs.PMID:38407147 | DOI:10.1177/10600280241231116 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 26, 2024 Category: Drugs & Pharmacology Authors: Yi Zhao Yuzhou Zhang Lin Yang Kanghuai Zhang Sha Li Source Type: research
Safety Profile of Selective Serotonin Reuptake Inhibitors in Real-World Settings: A Pharmacovigilance Study Based on FDA Adverse Event Reporting System
CONCLUSIONS AND RELEVANCE: Most of our findings are consistent with those reported previously, but some AEs were not previously identified. However, AEs attributed to SSRIs remain ambiguous, warranting further validation. Applying data-mining methods to the FAERS database can provide additional insights that can assist in appropriately utilizing SSRIs.PMID:38407147 | DOI:10.1177/10600280241231116 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 26, 2024 Category: Drugs & Pharmacology Authors: Yi Zhao Yuzhou Zhang Lin Yang Kanghuai Zhang Sha Li Source Type: research
Safety Profile of Selective Serotonin Reuptake Inhibitors in Real-World Settings: A Pharmacovigilance Study Based on FDA Adverse Event Reporting System
CONCLUSIONS AND RELEVANCE: Most of our findings are consistent with those reported previously, but some AEs were not previously identified. However, AEs attributed to SSRIs remain ambiguous, warranting further validation. Applying data-mining methods to the FAERS database can provide additional insights that can assist in appropriately utilizing SSRIs.PMID:38407147 | DOI:10.1177/10600280241231116 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 26, 2024 Category: Drugs & Pharmacology Authors: Yi Zhao Yuzhou Zhang Lin Yang Kanghuai Zhang Sha Li Source Type: research
Safety Profile of Selective Serotonin Reuptake Inhibitors in Real-World Settings: A Pharmacovigilance Study Based on FDA Adverse Event Reporting System
CONCLUSIONS AND RELEVANCE: Most of our findings are consistent with those reported previously, but some AEs were not previously identified. However, AEs attributed to SSRIs remain ambiguous, warranting further validation. Applying data-mining methods to the FAERS database can provide additional insights that can assist in appropriately utilizing SSRIs.PMID:38407147 | DOI:10.1177/10600280241231116 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 26, 2024 Category: Drugs & Pharmacology Authors: Yi Zhao Yuzhou Zhang Lin Yang Kanghuai Zhang Sha Li Source Type: research
Safety Profile of Selective Serotonin Reuptake Inhibitors in Real-World Settings: A Pharmacovigilance Study Based on FDA Adverse Event Reporting System
CONCLUSIONS AND RELEVANCE: Most of our findings are consistent with those reported previously, but some AEs were not previously identified. However, AEs attributed to SSRIs remain ambiguous, warranting further validation. Applying data-mining methods to the FAERS database can provide additional insights that can assist in appropriately utilizing SSRIs.PMID:38407147 | DOI:10.1177/10600280241231116 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - February 26, 2024 Category: Drugs & Pharmacology Authors: Yi Zhao Yuzhou Zhang Lin Yang Kanghuai Zhang Sha Li Source Type: research
Cancers, Vol. 16, Pages 885: Inhibition of TNBC Cell Growth by Paroxetine: Induction of Apoptosis and Blockage of Autophagy Flux
This study aimed to examine the impact of PX on TNBC cells in vitro as both a standalone treatment and in conjunction with other pharmaceutical agents. Cell viability was measured using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay, apoptosis was assessed through flow cytometry, and the effects on signaling pathways were analyzed using RNA sequencing and Western blot techniques. Furthermore, a subcutaneous tumor model was utilized to assess the in vivo efficacy of combination therapy on tumor growth. The results of our study suggest that PX may activate the Ca2+-dependent mitochondria-med...
Source: Cancers - February 22, 2024 Category: Cancer & Oncology Authors: Qianrui Huang Mengling Wu Yamin Pu Junyou Zhou Yiqian Zhang Ru Li Yong Xia Yiwen Zhang Yimei Ma Tags: Article Source Type: research
Pharmacological management of gambling disorder: an update of the literature
Expert Rev Neurother. 2024 Feb 15. doi: 10.1080/14737175.2024.2316833. Online ahead of print.ABSTRACTINTRODUCTION: Gambling disorder (GD) is a mental health condition characterized by persistent and problematic betting behavior. GD generates distress and impairment, and treatment options include psychological and pharmacological interventions.AREAS COVERED: This narrative review explores existing pharmacological treatments for GD. The following classes of medications were considered: opioid-receptor antagonists (e.g. naltrexone and nalmefene), serotonin reuptake inhibitors (e.g. fluvoxamine, paroxetine, sertraline, escital...
Source: Expert Review of Neurotherapeutics - February 15, 2024 Category: Neurology Authors: Gemma Mestre-Bach Marc N Potenza Source Type: research
