The place of selective serotonin reuptake inhibitors (SSRIs) in the treatment of depressive disorders in children and adolescents. Recommendations of the Main Board of the Polish Psychiatric Association. Part 2 - pharmacological properties and safety of use
Psychiatr Pol. 2023 Oct 31;57(5):917-940. doi: 10.12740/PP/171464. Epub 2023 Oct 31.ABSTRACTThe aim of the study was to review studies evaluating the pharmacodynamic properties of selective serotonin reuptake inhibitors (SSRIs) and their safety. SSRIs in patients <18 years of age sometimes have different pharmacokinetic parameters compared to adults, which has a significant impact on their effectiveness and tolerance. The concentration of fluoxetine, fluvoxamine or paroxetine is about 2 times higher in children compared to adolescents and adults, which should be taken into account at the stage of both drug introduction ...
Source: Psychiatria Polska - February 12, 2024 Category: Psychiatry Authors: Ma łgorzata Honorata Janas-Kozik Agnieszka S łopień Barbara Remberk Marcin Siwek Source Type: research

Separation and confinement anxiety in a golden retriever × standard poodle dog
Can Vet J. 2024 Feb;65(2):141-145.ABSTRACTAn 8-month-old spayed female golden retriever × standard poodle dog was presented for assessment because of vocalization, destructive behavior, and urination when left home alone and confined in a crate. Previous treatments included multiple medications, graduated departures, decoupling of departure cues, and punishmentbased techniques. Adverse reactions to paroxetine and lorazepam were noted before successful treatment with clomipramine, "safe haven" training, and behavior modification. Key clinical message: Separation anxiety is a common behavioral disorder in dogs. It is often ...
Source: The Canadian Veterinary Journal - February 2, 2024 Category: Veterinary Research Authors: Anneliese Heinrich Christine Calder Source Type: research

Separation and confinement anxiety in a golden retriever × standard poodle dog
Can Vet J. 2024 Feb;65(2):141-145.ABSTRACTAn 8-month-old spayed female golden retriever × standard poodle dog was presented for assessment because of vocalization, destructive behavior, and urination when left home alone and confined in a crate. Previous treatments included multiple medications, graduated departures, decoupling of departure cues, and punishmentbased techniques. Adverse reactions to paroxetine and lorazepam were noted before successful treatment with clomipramine, "safe haven" training, and behavior modification. Key clinical message: Separation anxiety is a common behavioral disorder in dogs. It is often ...
Source: The Canadian Veterinary Journal - February 2, 2024 Category: Veterinary Research Authors: Anneliese Heinrich Christine Calder Source Type: research

Separation and confinement anxiety in a golden retriever × standard poodle dog
Can Vet J. 2024 Feb;65(2):141-145.ABSTRACTAn 8-month-old spayed female golden retriever × standard poodle dog was presented for assessment because of vocalization, destructive behavior, and urination when left home alone and confined in a crate. Previous treatments included multiple medications, graduated departures, decoupling of departure cues, and punishmentbased techniques. Adverse reactions to paroxetine and lorazepam were noted before successful treatment with clomipramine, "safe haven" training, and behavior modification. Key clinical message: Separation anxiety is a common behavioral disorder in dogs. It is often ...
Source: The Canadian Veterinary Journal - February 2, 2024 Category: Veterinary Research Authors: Anneliese Heinrich Christine Calder Source Type: research

Separation and confinement anxiety in a golden retriever × standard poodle dog
Can Vet J. 2024 Feb;65(2):141-145.ABSTRACTAn 8-month-old spayed female golden retriever × standard poodle dog was presented for assessment because of vocalization, destructive behavior, and urination when left home alone and confined in a crate. Previous treatments included multiple medications, graduated departures, decoupling of departure cues, and punishmentbased techniques. Adverse reactions to paroxetine and lorazepam were noted before successful treatment with clomipramine, "safe haven" training, and behavior modification. Key clinical message: Separation anxiety is a common behavioral disorder in dogs. It is often ...
Source: The Canadian Veterinary Journal - February 2, 2024 Category: Veterinary Research Authors: Anneliese Heinrich Christine Calder Source Type: research