Changes in cardiac functions in patients treated with parathyroidectomy for secondary hyperparathyroidism
AbstractOur study aims to investigate the changes in cardiac functions, especially myocardial performance index (MPI), in patients who underwent parathyroidectomy for secondary hyperparathyroidism. Patients who underwent parathyroidectomy for secondary hyperparathyroidism between June 2010 and September 2021 were analyzed retrospectively. The patients were divided into two groups: those who underwent total parathyroidectomy (group 1) and those who underwent subtotal parathyroidectomy (group 2). The groups were compared according to the echocardiogram findings performed in the preoperative period and the postoperative sixth...
Source: Updates in Surgery - March 26, 2024 Category: Surgery Source Type: research
Complex Primary Hyperparathyroidism
Primary hyperparathyroidism can be sporadic or part of a genetic syndrome, such as MEN1 or HPT-JT. Diagnosis of hereditary HPT requires a thorough history and physical. Parathyroidectomy is curative with greater than 95% success. However, some patients have persistent or recurrent disease requiring reoperation. Reoperative parathyroidectomy is technically challenging, and localizing the pathologic gland can difficult. Patients needing reoperation should undergo evaluation by a high-volume surgeon. Care should be taken to obtain all of the preoperative workup and operative note from the initial surgery. Radioguided parathyr...
Source: Surgical Clinics of North America - March 23, 2024 Category: Surgery Authors: Sanjana Balachandra, Jessica Fazendin, Herbert Chen Source Type: research
Intraoperative radio-guided localization of parathyroid adenomas using 3D freehand SPECT technology
AbstractParathyroidectomy for primary hyperparathyroidism (PHPT) could have poor outcomes, even with accurate preoperative localization of the adenomas, because their intraoperative localization can be challenging. Freehand single photon emission computed tomography (fhSPECT) is a new technique for radio-guided intraoperative navigation. Its use during parathyroidectomy could be useful and such data are limited. We herein present our experience on the feasibility of fhSPECT for intraoperative detection of abnormal parathyroid glands. We retrospectively reviewed the clinical data of 55 patients (30 –77 years old) with PH...
Source: Updates in Surgery - March 22, 2024 Category: Surgery Source Type: research
Surgical Management of Secondary and Tertiary Hyperparathyroidism
Secondary hyperparathyroidism (SHPT) often arises from kidney disease and is characterized by elevated parathyroid hormone (PTH) levels. The reported optimal PTH level to balance the compensatory physiologic response in SHPT with the pathologic morbidity and mortality has changed over time with our evolving understanding. Parathyroidectomy for kidney-related hyperparathyroidism requires consideration of the patient ’s dialysis status, potential for kidney transplantation, and medical history. Extent of parathyroidectomy and intraoperative decision-making requires consideration to maximize cure with the risk of permanent ...
Source: Surgical Clinics of North America - March 21, 2024 Category: Surgery Authors: Marisa Bartz-Kurycki, Sophie Dream Source Type: research
Comparison of normocalcemic versus hypercalcemic primary hyperparathyroidism in a hypercalciuric renal stone population
CONCLUSION: Our data show the relevance of dynamic tests to unmask NHPT in hypercalciuric renal stone patients.PMID:38497124 | DOI:10.1210/clinem/dgae162 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - March 18, 2024 Category: Endocrinology Authors: Halimi Caroline Bor Clemence Chieze Remi Saint-Jacques Camille P érié Sophie Wagner Isabelle Talbot Jean-Noel Montravers Fran çoise Letavernier Emmanuel Buob David Daudon Michel Frochot Vincent Haymann Jean-Philippe Source Type: research
Abnormalities of serum magnesium levels in dialysis patients undergoing parathyroidectomy
In conclusion, magnesium abnormalities play a minor role in hungry bone syndrome after parathyroidectomy for secondary hyperparathyroidism. Patients with higher serum magnesium levels had greater severity of pruritus. (Source: Updates in Surgery)
Source: Updates in Surgery - March 13, 2024 Category: Surgery Source Type: research
The Role of Demographic and Clinical Factors in Germline Mutation Testing for Patients with Primary Hyperparathyroidism
CONCLUSIONS: Most patients with onset of hypercalcemia age ≤ 40 years, positive FHx, or other clinical concerns underwent genetic counseling, while most with MGD did not. As no germline mutations were identified in patients with MGD alone, further investigation of MGD as a sole indication for genetic counseling may be warranted.PMID:38459417 | DOI:10.1245/s10434-024-15104-3 (Source: Ann Oncol)
Source: Ann Oncol - March 8, 2024 Category: Cancer & Oncology Authors: Patrick T Hangge Sophie Dream Tina W F Yen Kara Doffek Samantha M Stachowiak Joseph Shaker Douglas B Evans Tracy S Wang Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Factors affecting the rates of incidental parathyroidectomy during thyroidectomy
CONCLUSIONS: We found that the complication rate during the resident training process was the same as that of experienced general surgeons. A thyroidectomy can be safely performed by senior residents during residential training.PMID:38445585 | DOI:10.1308/rcsann.2024.0019 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: H E Arslan S Zeren A C Yildirim M F Ekici O Arik M C Algin Source Type: research
Surgical tactics of parathyroidectomy: Should we abandon the use of ioPTH?
Anatomical and physiological knowledge of the parathyroid glands is fundamental for achieving curative surgery by an endocrine surgeon. The upper parathyroid glands originate from the fourth pharyngeal pouch, and the lower ones from the third, along with the thymus. Therefore, it is possible to find some of the lower parathyroids inside the thymus or even in the anterior mediastinum, while the upper ones can migrate to the posterior mediastinum (Fig. 1).1 The ectopic location of a pathological parathyroid gland is a common cause of parathyroidectomy failure and persistent hyperparathyroidism. (Source: American Journal of Surgery)
Source: American Journal of Surgery - March 4, 2024 Category: Surgery Authors: Joaqu ín Gómez-Ramírez, Raquel Arranz Jiménez Tags: My Thoughts / My Surgical Practice Source Type: research
Don ’t chase the adenoma: A probabilistic approach to imaging before parathyroidectomy
Preoperative imaging before parathyroidectomy can localize adenomas and reduce unnecessary bilateral neck explorations. We hypothesized that (1) the utility of preoperative imaging varies substantially depending on the preoperative probability of having adenoma(s) and (2) that a selective imaging approach based on this probability could avoid unnecessary patient costs and radiation. (Source: Surgery)
Source: Surgery - March 2, 2024 Category: Surgery Authors: Nicole Lunardi, Allison Jacob, Dawn Elfenbein, David F. Schneider, Kristin Long, Simon A. Holoubek, Erin MacKinney, Alexander Chiu, Rebecca S. Sippel, Courtney J. Balentine Source Type: research
