A young woman with chest pain, cath lab activated
This case came from a friend whose sister was the patient. She knew I was interested in ECGs, so she took a photo of this one.A young woman presented with acute chest pain.This was her presenting ECG:What do you think?This is clearly Brugada phenotype.  There is downsloping ST Elevation in V1 and V2.  To an experienced interpreter, it is clearly not due to OMI.  And it is clearly Brugada phenotype.The conventional algorithm did not interpret Brugada. In fact, it read: ** **ACUTE MI / STEMI ** **The physicians caring for the patient activated the cath lab for " STEMI " .The interventionalist and cath tea...
Source: Dr. Smith's ECG Blog - April 6, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs

poem
 IthacaOnce I finally left the islandOf Calypso the highway became an endless Series of off-ramps and mergingsEach exit sign an indecipherable medleyOf directional words — North and south, east and westFuture and past, here or now —All mixed up in inexplicable combinations That made no geographical sense The GPS on my phone showedOnly a red dot moving alongA single black line relative to nothing elseWhich is the definition Of going nowhere fast Time lysed itself from spaceWhile space moved on to whatever comes after time  Three minutes allegedly elapsedAccording to the digit...
Source: Buckeye Surgeon - April 6, 2024 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

An Urgent Call to Raise Awareness of Heart Disease in Women
By KELLY CARROLL There is a dire need to raise awareness about heart disease in women. It is the number one killer of American women, and key data points reveal a lack of cognizance among doctors and women. An assessment of primary care physicians published in 2019 revealed that only 22% felt extremely well prepared to evaluate cardiovascular disease risks in female patients. A 2019 survey of American women showed that just 44% recognized heart disease as the number one cause of death in women. Ten years earlier, in 2009, the same survey found that 65% of American women recognized heart disease as the leading cause o...
Source: The Health Care Blog - April 5, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice heart disease Kelly Carroll Life Essential 8 prevention Womens health Source Type: blogs

Chronic Pain Accelerates Brain Aging, Perhaps via Inflammation
A range of conditions produce chronic pain in muscle and skeletal tissue. While conditions such as osteoathritis are comparatively well understood, the etiology of chronic muscular pain disorders such as myofascial pain syndrome is poorly understood and treatment options are consequently limited. Here, researchers analyze available epidemiological data on knee osteoarthritis, and show that it suggests an inflammatory link between chronic pain and an accelerated pace of degenerative brain aging. Individuals suffering from chronic musculoskeletal pain (CMP) may face a higher high risk of brain aging. CMP is a leadin...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes. « Back to Top A Skeptical View of the Role of Nuclear DNA Damage in Aging https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/ It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What happened after the Cath lab was activated for a chest pain patient with this ECG?
Sent by anonymous, written by Pendell MeyersI received a text with this image and no other information:What do you think?I simply texted back: " Definite posterior OMI. " The person I was texting knows implicitly based on our experience together that I mean " Definite posterior OMI, assuming the patient ' s clinical presentation is consistent with ACS. "The patient was a middle-aged female who had acute chest pain of approximately 6 hours duration. The pain was still active at the time of evaluation.Queen of Hearts:You can see that the Queen is most concerned with the ST depression in V2 and V3The physician activated ...
Source: Dr. Smith's ECG Blog - March 31, 2024 Category: Cardiology Authors: Pendell Source Type: blogs

Low-frequency ultrasound for pain relief [PODCAST]
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! We welcome L. Joseph Parker, a research physician, as we delve into a study that explores the potential of low-frequency ultrasound waves in pain management. Joseph will guide us through the intriguing findings of this study, shedding light on how targeted Read more… Low-frequency ultrasound for pain relief [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 30, 2024 Category: General Medicine Authors: Tags: Podcast Pain Management Source Type: blogs

Microskills to be a team player: workplace violence
A patient, intoxicated with alcohol, comes into the emergency department complaining of chest pain. The nurse and the ECG tech need help as the patient is yelling, flailing his arms, and trying to stand up out of bed while stumbling. The nurse puts a blood pressure cuff on his arm and a pulse oximeter probe Read more… Microskills to be a team player: workplace violence originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 30, 2024 Category: General Medicine Authors: Tags: Physician Emergency Medicine Source Type: blogs

Real pain deserves real treatment
When a patient comes to us and describes confusing symptoms that don’t seem to fit into any immediate category, we can see it in two different ways: as a challenge, we can rise to, a riddle to solve … or we can see it as an opportunity to denigrate the patient, to imply that they Read more… Real pain deserves real treatment originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 29, 2024 Category: General Medicine Authors: Tags: Conditions Rheumatology Source Type: blogs

How Enhanced Recovery After Surgery solves our opioid problems
In retrospect, we were an addicted nation waiting to happen. Not from a self-indulgent culture, not from an unwillingness to suffer hardship, nor any of the generational criticisms of lack of grit. Our opioid crisis derives from an impatient culture that fears loss of health more than health care profit. With pain as most people’s Read more… How Enhanced Recovery After Surgery solves our opioid problems originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 28, 2024 Category: General Medicine Authors: Tags: Meds Medications Pain Management Source Type: blogs

Brugada Syndrome
Transcript of the video: Brugada Syndrome was described by Brugada brothers in 1992 as right bundle branch block pattern in anterior leads with ST segment elevation and syncope or sudden cardiac death and it was later in 1998, that the genetic basis of the disease was identified, with mutations in sodium channel. Later on, several other mutations have been attributed to cause the ECG pattern in Brugada syndrome. I am always happy to see this ECG of Brugada syndrome sent to me by Professor Josep Brugada, in 2001, for the inaugural issue of the Indian Pacing and Electrophysiology Journal, which I started in 2001. And, this r...
Source: Cardiophile MD - March 28, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Apigenin, Sleep, and Aging
For those following research into efforts to upregulate NAD+ levels to improve mitochondrial function, this paper is an interesting sidebar. Some degree of loss of NAD+ emerges from increased activity of CD38. Apigenin is a dietary supplement that can modestly influence both sleep and pace of aging, the latter in short-lived laboratory species at least. Apigenin can increase NAD+ levels by inhibiting CD38 activity. Like much of metabolism, this is all very interesting, but the effect sizes are nothing to write home about. If upregulating NAD+ levels is the goal, you'll do better by exercising. The fundamental flaw in so mu...
Source: Fight Aging! - March 26, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A man in his 50s with shortness of breath
Sent by Tom Fiero, written by Pendell Meyers A man in his 50s presented with acute shortness of breath. Unfortunately we do not have access to the patients presenting vital signs.Here is his ECG:Original image, suboptimal qualityQuality improved with PM Cardio digitizationThe ECG is highly suggestive of acute right heart strain, with sinus tachycardia, S1Q3T3, and T wave inversions in anterior and inferior with morphology consistent with acute right heart strain. There is also STE in lead III with reciprocal depression in aVL and I, as well as some subendocardial ischemia pattern with STD in V5-V6 and STE in aVR. Thus...
Source: Dr. Smith's ECG Blog - March 26, 2024 Category: Cardiology Authors: Pendell Source Type: blogs

Predicting the Order of Arrival of the First Rejuvenation Therapies
It has been going on eight years since I last speculated on the order of arrival of the first rejuvenation therapies. Tempus fugit, and time for an updated version! Eight years is a long enough span of time for the first of those rejuvenation therapies to now exist, albeit in a prototypical form, arguably proven in principle but not concretely. The world progresses but my biases remain much the same: the first rejuvenation therapies to work well enough to merit the name will be based on the SENS vision, that aging is at root caused by a few classes of accumulated cell and tissue damage, and biotechnologies that either repa...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Medicine as a public good
Medicine is unlike most other goods and services in the extent to which it has important positive externalities – that is, benefits for people outside of the transaction, who are not the providers or consumers. (Of course it has negative externalities as well, including carbon emissions and notably, a huge quantity of plastic waste.) A straightforward positive externality is infectious disease control. Prev enting or curing infectious diseases prevents them from being transmitted to others. This is an immense benefit to society that goes far beyond the direct value to people who are vaccinated or treated.Another positive...
Source: Stayin' Alive - March 25, 2024 Category: American Health Source Type: blogs