Beyond the headlines: the truth about weight loss drugs [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! We sit down with David Ahn, an endocrinologist. Join us as we delve into the impact of weight-loss drugs, the role of incretin medications, and their potential to reshape our approach to obesity and overall health. David Ahn is an endocrinologist and chief of diabetes Read more… Beyond the headlines: the truth about weight loss drugs [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 7, 2024 Category: General Medicine Authors: Tags: Podcast Diabetes Endocrinology Source Type: blogs

Value Based Care – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 5, 2024 Category: Information Technology Authors: John Lynn Tags: Administration Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations Revenue Cycle Management 2024 Health IT Predictions 9amHealth Andreessen Horowitz Anthony Hudson Anton Kittleberger Source Type: blogs

Telehealth and VR – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 4, 2024 Category: Information Technology Authors: John Lynn Tags: Ambulatory C-Suite Leadership Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring 2024 Health IT Predictions 98point6 Technologies Agora Andrew Norden Anish Sebastian Artisig Source Type: blogs

Twin Health Secures $50M to Expand its Groundbreaking Whole Body Digital Twin Technology and Service to Reverse Chronic Metabolic Disease
Investment Fuels Twin Health’s Mission to Revolutionize Chronic Metabolic Disease Prevention and Reversal with Cutting-Edge Science, Precision Guidance, and Licensed Clinical Care Team Twin Health, creators of the Whole Body Digital Twin service for reversing, improving, and preventing chronic metabolic diseases, announced securing $50 million in funding to continue expanding its groundbreaking technology and clinical service solutions for more members across the United States. Twin Health introduced the Whole Body Digital Twin, a dynamic model of each individual’s unique metabolism, powered by artificial int...
Source: EMR and HIPAA - January 4, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Health IT Funding Health IT Fundings Health IT Investment Helena ICONIQ Growth Jahangir Mohammed Kevin Johnson Peak XV Sofina Temasek Twin Health Source Type: blogs

Aptamers to Reduce Inflammatory AGE-RAGE Interaction
Researchers here discuss the use of aptamers that can bind to advanced glycation endproducts (AGEs). This prevents the AGEs from themselves binding to the receptor for AGEs (RAGE), an interaction that provokes inflammation. A sizable presence of circulating, short-lived AGEs is characteristic of the abnormal metabolism of obesity and obesity-related conditions such as type 2 diabetes. It is an open question as to how much of a contribution to the chronic inflammation of aging is provided by AGEs in people of a normal weight, eating a basically sensible diet, however. The only way to find out is to test a therapy of this na...
Source: Fight Aging! - January 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

It is Never Too Late to Improve Health by Reducing Calorie Intake
In this study, researchers looked specifically at male flies. Young flies switched from a high calorie to a low-calorie diet at 20 days old lived very long lives, similar to the flies fed a low-calorie diet from day one. What surprised the researchers was that switching the flies' diet to a low calorie one remained a reliable way to extend lifespan even for old flies in ill health. The older insects raised on the high calorie diet had more lipids in their bodies, and they expended more energy defending their bodies from reactive oxygen species. They also had a higher death rate than flies raised on the low-calorie diet. Bu...
Source: Fight Aging! - January 1, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, January 1st 2024
Discussion of What is Need to Speed the Pace at which Drugs to Treat Aging Arrive in the Clinic Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline Reviewing What is Known of the Mechanisms of Taurine Supplementation Relevant to Aging and Metabolism Blunt Thoughts on Calculating the Revealed Value of Human Life A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition Towards Adjustment of the Gut Microbiome to Slow Aging Gene Therapy Enhances Object Recognition Memory in Young and Old Mice Benefits of Sem...
Source: Fight Aging! - December 31, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition
The market has been in the doldrums and it has been a tough year for fundraising, both for non-profits and biotech startups. The conferences have exhibited more of an academic focus as companies tightened belts and postponed investment rounds, while investors stayed home. Not that this halts the flow of hype for some projects, and nor has it slowed media commentary on the longevity industry as it presently stands. A few of the articles in that commmentary are even interesting to read! The field has grown and is more mature now than has ever been the case. Biotech of all forms is a challenging field with a high failure rate...
Source: Fight Aging! - December 29, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Reviewing What is Known of the Mechanisms of Taurine Supplementation Relevant to Aging and Metabolism
Taurine is a semi-essential amino acid. Dietary taurine supplementation has been shown to modestly slow aging in mice, though as for all such interventions there is always the question of whether it will prove to be less useful in humans, and also whether these results in mice will be disproved by the much more rigorous Interventions Testing Program (ITP), once that group gets around to assessing taurine supplementation. Few of the numerous interventions thought to modestly slow aging in mice on the basis of earlier research actually held up once subjected to the ITP degree of experimental rigor. Speculatively, taur...
Source: Fight Aging! - December 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline
Senescent cells are created throughout the body at all stages of life, largely when somatic cells reach the Hayflick limit on replication. Senescent cells cease replication and begin to energetically produce pro-growth, pro-inflammatory factors, attracting the attention of the immune system and otherwise changing the behavior of surrounding cells. Cell stress and mutational damage can induce senescence, and in this case senescence is a mechanism that acts to limit the risk of cancer. Tissue injury also produces senescent cells, and here they help to coordinate the activities of the many different cell types that become inv...
Source: Fight Aging! - December 26, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Benefits of Semaglutide in Heart Failure are not Just Due to Weight Loss, in Mice at Least
This study investigated semaglutide, a glucagon-like peptide-1 receptor agonist that induces significant weight loss in patients with obesity and/or type 2 diabetes mellitus and has been associated with improved cardiovascular outcomes. In a mouse model of HFpEF that was caused by advanced aging, female sex, obesity, and type 2 diabetes mellitus, semaglutide, compared with weight loss induced by pair feeding, improved the cardiometabolic profile, cardiac structure, and cardiac function. Mechanistically, transcriptomic, and proteomic analyses revealed that semaglutide improved left ventricular cytoskeleton function a...
Source: Fight Aging! - December 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Breaking down weight management: insights from a bariatric expert [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Maria Iliakova, a bariatric and general surgeon. In this episode, we’ll explore essential topics in weight management and bariatric surgery. Discover effective ways to start conversations about weight with patients, learn when to refer to a bariatric specialist, and understand the role of Read more… Breaking down weight management: insights from a bariatric expert [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 23, 2023 Category: General Medicine Authors: Tags: Podcast Obesity Source Type: blogs

Season Health Announces Strategic Asset Acquisition from Wellory to Expand Clinical Network of Registered Dietitians and Insurance Coverage
Season Health, the leading integrated food-as-medicine platform, today announced the closing of a strategic acquisition of clinical assets from Wellory, one of the largest networks of registered dietitians in the country providing medical nutrition therapy to patients nationwide. This accelerates Season’s growth by significantly expanding its provider network and its ability to offer comprehensive, personalized nutrition care to more patients, including those looking for in-network benefits. Since its founding in 2019 by Emily Hochman and Jeni Fahy, Wellory has focused on unlocking access to quality nutrition care se...
Source: EMR and HIPAA - December 21, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT 8VC Andreessen Horowitz Emily Hochman Health IT Acquisitions Healthcare M&A Jeni Fahy Josh Hix LRVHealth Season Season Health Wellory Source Type: blogs

Vida Health Announces $28.5 Million in Funding; Appoints Joe Murad CEO
Investment to Support Key Growth Initiatives and Drive Continued Focus on Improving Access to Effective, Affordable, and Sustainable Cardiometabolic Care Treatments Vida Health today announced it has closed $28.5 million in financing led by existing investors, including General Atlantic, Ally Bridge, Canvas Ventures, Hercules Capital, and other insiders. The company also named Joe Murad as Chief Executive Officer. Murad brings more than two decades of experience leading healthcare technology companies, with a demonstrated ability to guide venture-backed businesses from early stages through phases of significant growth. Mur...
Source: EMR and HIPAA - December 18, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Ally Bridge Canvas Ventures General Atlantic Health IT Funding Health IT Fundings Health IT Investment Hercules Capital Joe Murad Stephanie Tilenius Vida Health Source Type: blogs

Ozempic: miracle drug or a band-aid for obesity?
An excerpt from Dr. T’s Drop the Fat Diet: 12 Steps to Leaner You Forever. Semaglutide, a medication often marketed as Ozempic, Wegovy, or Rybelsus, has gained immense popularity in recent years. This is especially true in an age where diabetes and obesity are on the rise. The medication is being seen as a panacea Read more… Ozempic: miracle drug or a band-aid for obesity? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 16, 2023 Category: General Medicine Authors: Tags: Meds Obesity Source Type: blogs