Consensus document on the management of hyperkalemia
Nefrologia (Engl Ed). 2024 Jan 1:S2013-2514(23)00178-5. doi: 10.1016/j.nefroe.2023.12.002. Online ahead of print.ABSTRACTHyperkalaemia is a common electrolyte imbalance with potentially serious short-, medium- and long-term consequences on morbidity and mortality rates and the use of national health service resources. The fact that different medical specialities can manage hyperkalaemia makes it important to have a unified approach, and the recent availability of new specific drug treatments means that the approach needs to be updated. This consensus document from the scientific societies most directly involved in the mana...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - January 3, 2024 Category: Urology & Nephrology Authors: Alberto Ortiz Carmen Del Arco Gal án Jos é Carlos Fernández-García Jorge G ómez Cerezo Rosa Ib án Ochoa Julio N úñez Francisco Pita Guti érrez Juan F Navarro-Gonz ález Source Type: research

GSE246622 Single-cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus (RSV) disease in infants
Contributors : Nevena Zivanovic ; Deniz Öner ; Yann Abraham ; Joseph McGinley ; Simon B Drysdale ; Joanne G Wildenbeest ; Marjolein Crabbe ; Greet Vanhoof ; Kim Thys ; Ryan S Thwaites ; Hannah Robinson ; Louis Bont ; Peter J Openshaw ; Federico Martinón-Torres ; Andrew J Pollard ; Jeroen AerssensSeries Type : Expression profiling by arrayOrganism : Homo sapiensWhile the majority of infants infected with respiratory syncytial virus (RSV) exhibit mild or no symptoms, approximately 3 million children under the age of five are hospitalized every year due to complications from RSV. This research sought to explore th...
Source: GEO: Gene Expression Omnibus - January 3, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

Full Engagement with the NHS in an integrated age: reflections on past endeavours (the Wanless Report) and current challenges (the  anti-vaxxer movement)
Full Engagement with the NHS in an integrated age: reflections on past endeavours (the Wanless Report) and current challenges (the anti-vaxxer movement) Jill Manthorpe, Steve Iliffe, Richard Bourne Journal of Integrated Care, Vol. ahead-of-print, No. ahead-of-print, pp.- It is over 20 years since the publication of the Wanless Report, “Securing our Future Health: Taking a Long-Term View”. The Wanless Report argued that the National Health Service (NHS) would survive in its current form only if the population became “fully engaged” with it.In this discussion paper, the authors explored what “fully engaged” mean...
Source: Journal of Integrated Care - December 28, 2023 Category: International Medicine & Public Health Authors: Jill Manthorpe Steve Iliffe Richard Bourne Source Type: research

Leave for informally admitted patients: a review of written guidance produced by mental health services in England and Wales
Russell Ashmore Mental Health Review Journal, Vol. ahead-of-print, No. ahead-of-print, pp.- The purpose of this paper is to report on the use and content of written guidance produced by mental health services in England and Wales describing hospital leave for informally admitted patients.Guidance on leave was requested from National Health Service (NHS) mental health trusts in England and health boards in Wales (n = 61) using a Freedom of Information submission. Data were analysed using content analysis.In total, 32 organisations had a leave policy for informal patients. Policies varied considerably in content and quality...
Source: Mental Health Review Journal - December 22, 2023 Category: Psychiatry Authors: Russell Ashmore Source Type: research

Impact of diabetes on medical costs in the pre- and postoperative year of lower extremity amputations in Belgium
Lower extremity amputations (LEAs), whether major or minor amputations, are associated with significantly reduced quality of life, high morbidity and mortality and a high financial burden [1]. In Western countries, most amputations are performed in the context of diabetic foot disease and/or peripheral arterial disease [2,3]. Data from the National Health Service in England for 2014 –2015 estimated expenditure of £837 million to £962 million on health-care costs related to foot ulceration and all amputations in individuals with diabetes, equivalent to 0.78–0.90 % of the entire health service’s budget [1]. (Source...
Source: Diabetes Research and Clinical Practice - December 22, 2023 Category: Endocrinology Authors: Patrick Lauwers, Jeroen M.H. Hendriks, Kristien Wouters, Johan Vanoverloop, Herv é Avalosse, Eveline Dirinck, Frank Nobels, Belgian Amputation Group Source Type: research

Cultural competence in NHS hearing aid clinics: a mixed-methods case study of services for Deaf British sign language users in the UK
This study identified and explored how National Health Service (NHS) hearing aid clinics address cultural competence concerning Deaf British Sign Language (BSL) users. This was approached by (i) investigating ... (Source: BMC Health Services Research)
Source: BMC Health Services Research - December 19, 2023 Category: General Medicine Authors: Celia Hulme, Alys Young, Katherine Rogers and Kevin J. Munro Tags: Research Source Type: research

The effectiveness of digital delivery versus group-based face-to-face delivery of the English National Health Service Type 2 Diabetes Prevention Programme: a non-inferiority retrospective cohort comparison study
Face-to-face group-based diabetes prevention programmes have been shown to be effective in many settings. Digital delivery may suit some patients, but research comparing the effectiveness of digital with face-... (Source: BMC Health Services Research)
Source: BMC Health Services Research - December 18, 2023 Category: General Medicine Authors: Antonia M. Marsden, Mark Hann, Emma Barron, Ben McGough, Elizabeth Murray, Jonathan Valabhji and Sarah Cotterill Tags: Research Source Type: research

Nurse identity: the misrepresentation of nursing in the media
Since 2019, the nursing profession has been frequently represented in mainstream media in the UK through the lenses of the COVID-19 pandemic and more recently, industrial action. In 2020, during COVID, we saw the nursing profession praised, with weekly neighbourhood applause and thanks to the National Health Service (NHS) staff schemes. In 2023, when, for the first time in history nurses voted to strike (fair pay for nursing), nurses again received media attention. Conversely, the media chose to report how striking nurses (and other health professional staff) contributed to long waiting lists in the NHS and unhelpfully, de...
Source: Evidence-Based Nursing - December 15, 2023 Category: Nursing Authors: Garcia, R., Qureshi, I. Tags: Editor's choice, Nursing issues Editorials Source Type: research

The usage of data in NHS primary care commissioning: a realist evaluation
To improve health outcomes and address mounting costs pressures, policy-makers have encouraged primary care commissioners in the British National Health Service (NHS) to increase the usage of data in decision-... (Source: BMC Family Practice)
Source: BMC Family Practice - December 14, 2023 Category: Primary Care Authors: Alexandra Jager, Chrysanthi Papoutsi and Geoff Wong Tags: Research Source Type: research

Frailty Assessment in Vascular OUtpatients Review (FAVOUR) protocol: single-centre prospective cohort study comparing feasibility and prognostic value of commonly used frailty assessment tools
Introduction Frailty has consistently demonstrated associations with poorer healthcare outcomes. Vascular guidelines have recognised the importance of frailty assessment. However, an abundance of frailty tools and a lack of prospective studies confirming suitability of routine frailty assessment in clinical practice has delayed the uptake of these guidelines. The Frailty Assessment in Vascular OUtpatients Review study speaks to this evidence gap. The primary aim is to assess feasibility of implementing routine frailty assessment in a reproducible outpatient setting. Secondary objectives include comparing prognostic values ...
Source: BMJ Open - December 9, 2023 Category: General Medicine Authors: Welsh, S. A., Hussey, K., Brittenden, J., Orr, D. J., Quinn, T. Tags: Open access, Surgery Source Type: research

The art of the possible? Supporting a patient safety culture in mental healthcare to maximise safety
This study aims to explore the perspectives of patient safety professionals about what works well and what could be done better to support a patient safety culture at the level of Trust strategy and serious incident governance.A total of 15 professionals with a role in serious incident management, from five mental health trusts in England, were interviewed using a semi-structured interview guide. Thematic analysis and qualitative description were used to analyse the data.Participants felt that actions to support a patient safety culture were challenging and required long-term and clinical commitment. Broadening the scope o...
Source: Mental Health Review Journal - December 8, 2023 Category: Psychiatry Authors: David P. Wood Rajan Nathan Catherine A. Robinson Rebecca McPhillips Source Type: research

Ten years of a neonatal screening program for hemoglobinopathies in Friuli-Venezia Giulia: first regional experience in Italy
We report our experience of 10 years of screening newborns for hemoglobinopathies in the Region of Friuli-Venezia Giulia, in which 7.7% of people come from malaria-endemic areas. Increased mobility and migratory flows bringing in hemoglobinopathy carriers from endemic areas have led to an increase in mutations in non-malarial countries, with a current incidence of around 4% in the newborns we tested. This means that hemoglobinopathies can be described as a rare condition. Our data show that incidence rates are comparable to those of other inherited disorders such as phenylketonuria, thereby justifying the inclusion of the ...
Source: Blood Transfusion - December 8, 2023 Category: Hematology Authors: Epifania R Testa Margherita Robazza Francesca Barbieri Laura Travan Maria P Miani Elisabetta Miorin Ingrid Toller Danica Dragovic Valentina Moretti Stefano Facchin Patrizia Valeri Luciana Geremia Valeria Brunetta Roberto Dall'Amico Andrea Bontadini Source Type: research

Ten years of a neonatal screening program for hemoglobinopathies in Friuli-Venezia Giulia: first regional experience in Italy
We report our experience of 10 years of screening newborns for hemoglobinopathies in the Region of Friuli-Venezia Giulia, in which 7.7% of people come from malaria-endemic areas. Increased mobility and migratory flows bringing in hemoglobinopathy carriers from endemic areas have led to an increase in mutations in non-malarial countries, with a current incidence of around 4% in the newborns we tested. This means that hemoglobinopathies can be described as a rare condition. Our data show that incidence rates are comparable to those of other inherited disorders such as phenylketonuria, thereby justifying the inclusion of the ...
Source: Blood Transfusion - December 8, 2023 Category: Hematology Authors: Epifania R Testa Margherita Robazza Francesca Barbieri Laura Travan Maria P Miani Elisabetta Miorin Ingrid Toller Danica Dragovic Valentina Moretti Stefano Facchin Patrizia Valeri Luciana Geremia Valeria Brunetta Roberto Dall'Amico Andrea Bontadini Source Type: research

Ten years of a neonatal screening program for hemoglobinopathies in Friuli-Venezia Giulia: first regional experience in Italy
We report our experience of 10 years of screening newborns for hemoglobinopathies in the Region of Friuli-Venezia Giulia, in which 7.7% of people come from malaria-endemic areas. Increased mobility and migratory flows bringing in hemoglobinopathy carriers from endemic areas have led to an increase in mutations in non-malarial countries, with a current incidence of around 4% in the newborns we tested. This means that hemoglobinopathies can be described as a rare condition. Our data show that incidence rates are comparable to those of other inherited disorders such as phenylketonuria, thereby justifying the inclusion of the ...
Source: Blood Transfusion - December 8, 2023 Category: Hematology Authors: Epifania R Testa Margherita Robazza Francesca Barbieri Laura Travan Maria P Miani Elisabetta Miorin Ingrid Toller Danica Dragovic Valentina Moretti Stefano Facchin Patrizia Valeri Luciana Geremia Valeria Brunetta Roberto Dall'Amico Andrea Bontadini Source Type: research