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Health outcomes after myocardial infarction: A population study of 56 million people in England
by Marlous Hall, Lesley Smith, Jianhua Wu, Chris Hayward, Jonathan A. Batty, Paul C. Lambert, Harry Hemingway, Chris P. Gale BackgroundThe occurrence of a range of health outcomes following myocardial infarction (MI) is unknown. Therefore, this study aimed to determine the long-term risk of major health outcomes following MI and generate sociodemographic stratified risk charts in order to inform care recommendations in the post-MI period and underpin shared decision making. Methods and findingsThis nationwide cohort study includes all individuals aged ≥18 years admitted to one of 229 National Health Service (NHS) Trusts ...
Source: PLoS Medicine - February 15, 2024 Category: Internal Medicine Authors: Marlous Hall Source Type: research

Cognitive Functional Therapy compared with usual physiotherapy care in people with persistent low back pain: A mixed methods feasibility randomised controlled trial in the United Kingdom National Health Service
To determine the feasibility of completing a definitive randomised controlled trial (RCT), evaluating the clinical and cost-effectiveness of Cognitive Functional Therapy (CFT) in comparison to usual physiotherapy care (UPC), for people with persistent low back pain (LBP). (Source: Physiotherapy)
Source: Physiotherapy - February 12, 2024 Category: Physiotherapy Authors: Christopher Newton, Gurpreet Singh, David Nolan, Vicky Booth, Claire Diver, Seth O ’Neill, Helen Purtill, Pip Logan, Kieran O’Sullivan, Peter O’Sullivan Source Type: research

AI assisted reader evaluation in acute CT head interpretation (AI-REACT): protocol for a multireader multicase study
Introduction A non-contrast CT head scan (NCCTH) is the most common cross-sectional imaging investigation requested in the emergency department. Advances in computer vision have led to development of several artificial intelligence (AI) tools to detect abnormalities on NCCTH. These tools are intended to provide clinical decision support for clinicians, rather than stand-alone diagnostic devices. However, validation studies mostly compare AI performance against radiologists, and there is relative paucity of evidence on the impact of AI assistance on other healthcare staff who review NCCTH in their daily clinical practice. ...
Source: BMJ Open - February 12, 2024 Category: General Medicine Authors: Fu, H., Novak, A., Robert, D., Kumar, S., Tanamala, S., Oke, J., Bhatia, K., Shah, R., Romsauerova, A., Das, T., Espinosa, A., Grzeda, M. T., Narbone, M., Dharmadhikari, R., Harrison, M., Vimalesvaran, K., Gooch, J., Woznitza, N., Salik, N., Campbell, A., Tags: Open access, Radiology and imaging Source Type: research

Mobile health biometrics to prescribe immediate remote physical activity for enhancing uptake to cardiac rehabilitation (MOTIVATE-CR+): protocol for a randomised controlled feasibility trial
Introduction Cardiac rehabilitation (CR) can reduce cardiovascular mortality and improve health-related quality of life. In the United Kingdom, patient uptake of CR remains low (52%), falling well short of the target in the 2019 National Health Service long-term plan (85%). Mobile health (mHealth) technologies, offering biometric data to patients and healthcare professionals, may bridge the gap between supervised exercise and physical activity advice, enabling patients to engage in regular long-term physically active lifestyles. This randomised controlled trial (RCT) will evaluate the feasibility of mHealth technology when...
Source: BMJ Open - February 12, 2024 Category: General Medicine Authors: Crozier, A., Cocks, M., Hesketh, K., Miller, G., Mcgregor, G., Thomas, L., Jones, H. Tags: Open access, Sports and exercise medicine Source Type: research

Manchester Intermittent Diet in Gestational Diabetes Acceptability Study (MIDDAS-GDM): a two-arm randomised feasibility protocol trial of an intermittent low-energy diet (ILED) in women with gestational diabetes and obesity in Greater Manchester
This study aims to test the safety, feasibility and acceptability of an ILED intervention among women with GDM compared with best National Health Service (NHS) care. Method and analysis We aim to recruit 48 women with GDM diagnosed between 24 and 30 weeks gestation from antenatal clinics at Wythenshawe and St Mary’s hospitals, Manchester Foundation Trust, over 13 months starting in November 2022. Participants will be randomised (1:1) to ILED (2 low-energy diet days/week of 1000 kcal and 5 days/week of the best NHS care healthy diet and physical activity advice) or best NHS care 7 days/week until delivery of their ba...
Source: BMJ Open - February 10, 2024 Category: General Medicine Authors: Dapre, E., Issa, B. G., Harvie, M., Su, T.-L., McMillan, B., Pilkington, A., Hanna, F., Vyas, A., Mackie, S., Yates, J., Evans, B., Mubita, W., Lombardelli, C. Tags: Open access, Diabetes and Endocrinology Source Type: research

Predicting Survival with Brain Metastases in the Stereotactic Radiosurgery Era: are Existing Prognostic Scores Still Relevant? Or Can we do Better?
Predicting survival is essential to tailoring treatment for patients diagnosed with brain metastases. We have evaluated the performance of widely used, validated prognostic scoring systems (Graded Prognostic Assessment and diagnosis-specific Graded Prognostic Assessment) in over 1000 ‘real-world’ patients treated with stereotactic radiosurgery to the brain, selected according to National Health Service commissioning criteria. Survival outcomes from our dataset were consistent with those predicted by the prognostic systems, but with certain cancer subtypes showing a significa ntly better survival than predicted. (Source: Clinical Oncology)
Source: Clinical Oncology - February 8, 2024 Category: Radiology Authors: M.W. Fittall, M. Brewer, J. de Boisanger, L. Kviat, A. Babiker, H. Taylor, F. Saran, J. Konadu, F. Solda, A. Creak, L.C. Welsh, N. Rosenfelder Tags: Original Article Source Type: research

Investigating healthcare workforce recruitment and retention: a mixed-methods study protocol
Introduction Although the sustainability of the health workforce has been identified as essential to achieving health and wider development objectives, challenges with securing and retaining the healthcare workforce persist. In the UK, there are notable shortages across a wide range of National Health Service (NHS) staff groups, with a high staff turnover indicating retention issues in the healthcare workforce. In addition, gaps exist in understanding the root cause of individual organisation’s workforce deficiencies and how their practice environment factors interact to impact workforce recruitment and retention. M...
Source: BMJ Open - February 8, 2024 Category: General Medicine Authors: Alkan, E., Cushen-Brewster, N., Anyanwu, P. Tags: Open access, Health services research Source Type: research