Mayo Clinic researchers recommend investments in vaccine safety in Nature commentary
The leaders of Mayo Clinic's Vaccine Research Group are emphasizing the need for increased long-term study of vaccines and their mechanisms with future safety of patients in mind. Gregory Poland, M.D., and Richard Kennedy, Ph.D., write in their commentary in the scientific journal Nature Reviews Immunology that greater focus on understanding vaccines' downstream effects, not only on immunity but also on all the other biological systems will provide information that can help make vaccines safer… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 25, 2022 Category: Research Source Type: news

Science Saturday:  Mayo researchers lay foundation for AI-based personalized cancer modeling
Like the maps that drivers use to get from one place to another, the goal of a medical diagnosis is to get you from where you are to where you want to be. A diagnosis takes a patient from symptoms to treatment, such as from lump to cure in the case of breast cancer. Medical "road maps" are built from painstakingly selected patient data that clarify risk factors, like a BRCA mutation for breast cancer,… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 19, 2022 Category: Research Source Type: news

Science Saturday: Identifying best candidates with avascular necrosis for regenerative alternative to hip replacement
A regenerative alternative to total hip replacement delayed the need for artificial implants by at least seven years for 35% of patients who had surgery to treat avascular necrosis. That condition occurs when blood flow to the hip joint known as the femoral head is constricted, causing bone cells to die. This Mayo Clinic research, which is published in Bone& Joint Open, also discovered that the size of the necrotic lesion and continued corticosteroid therapy affect the long-term… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 12, 2022 Category: Research Source Type: news

Breast cancer now leading cause of cancer death in African American/Black women
A new report by the American Cancer Society indicates that breast cancer has now surpassed lung cancer as the leading cause of cancer death among Black women. The news is one of the key findings in Cancer Statistics for African American/Black People 2022, published this week. “African American women are twice as likely to be diagnosed with breast cancer early when compared with Caucasian women, and unfortunately have three times the morality rate,” says Sabrina… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 11, 2022 Category: Research Source Type: news

Study finds that patients with alcohol-associated cirrhosis have worse outcomes in recovering from critical illness, compared with other cirrhosis patients
ROCHESTER, Minn. — Patients with alcohol-associated cirrhosis have poorer outcomes after ICU discharge, compared to patients with cirrhosis linked to other causes, according to new Mayo Clinic research. Cirrhosis is a scarring of the liver that damages function and can be life-threatening. Almost half of all cirrh osis deaths are attributed to chronic alcohol use disorder, with the rest caused by hepatitis and other forms of liver disease. Over 7 deaths per 100,000 worldwide are linked… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 25, 2022 Category: Research Source Type: news

Direct oral anticoagulants significantly decrease recurrent venous thrombosis for adult cancer patients, Mayo Clinic study finds
ROCHESTER, Minn. — Direct oral anticoagulants should be considered the standard of care to treat adult patients with cancer-associated thrombosis, according to a new, ongoing study by Mayo Clinic researchers. Thrombosis is a condition where blood clots form in blood vessels of the legs. These clots can travel to t he lungs and become lodged in blood vessels, causing a pulmonary embolism. Thrombotic outcomes increase mortality in cancer patients and are the second most common cause of… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 18, 2022 Category: Research Source Type: news

Science Saturday: 10 significant Mayo Clinic Center for Individualized Medicine studies of 2021
It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic's Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physicians have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses.  As a new year approaches, here's a look back at 10 of Mayo Clinic ’s influential precision… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 1, 2022 Category: Research Source Type: news

Mayo Clinic research finds immune system responds to mRNA treatment for cancer
ROCHESTER, Minn. ― Adding messenger RNA, or mRNA therapy improves the response to cancer immunotherapy in patients who weren't responding to the treatment, Mayo Clinic research shows. Immunotherapy uses the body’s immune system to prevent, control and eliminate cancer. The study is published in Cancer Immunology Research, a journal of the American Association for Cancer Research. The phrase messenger RNA and its acronym, mRNA, have become familiar to the public during the COVID-19 pandemic. The… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 15, 2021 Category: Research Source Type: news

Retrospective study finds that cancer drug also lowers blood glucose
ROCHESTER, Minnesota — Dasatinib, a drug that often is used to treat certain types of leukemia, may have antidiabetic effects comparable to medications used to treat diabetes, and with more research may become a novel therapy for diabetic patients, according to new research published in Mayo Clinic Proceedings. Dasati nib is a tyrosine kinase inhibitor used to treat tumors and malignant tissue, as well as chronic myelogenous leukemia. Researchers at Mayo Clinic and the University of… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 9, 2021 Category: Research Source Type: news

Seizure forecasting with wrist-worn devices possible for people with epilepsy, study shows
ROCHESTER, Minn. — Despite medications, surgery and neurostimulation devices, many people with epilepsy continue to have seizures. The unpredictable nature of seizures is severely limiting. If seizures could be reliably forecast, people with epilepsy could alter their activities, take a fast-acting medication or t urn up their neurostimulator to prevent a seizure or minimize its effects. A new study in Scientific Reports by Mayo Clinic researchers and international collaborators found patterns could be identified in patients… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 9, 2021 Category: Research Source Type: news

Mayo Clinic collaborates with Personalis Inc. to expand cancer genomic testing
ROCHESTER, Minn., and MENLO PARK, Calif. — Mayo Clinic announced an agreement on Tuesday, Oct. 12 that will allow it to offer clinical-grade comprehensive cancer genomic sequencing to cancer patients who choose to participate. Test results will be available to patients and their treating health care providers to guide therapeutic decisio ns, advance cancer research, and support the development of new diagnostic tests and therapies for cancer treatment. Mayo Clinic Cancer Center, Mayo Clinic's Department of… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 12, 2021 Category: Research Source Type: news

Mayo Clinic celebrates 35 years in Florida
JACKSONVILLE, Fla. — In the 35 years since its opening, Mayo Clinic in Florida has become one of the premier medical destination centers in the Southeast while garnering the No. 1 spot in U.S. News& World Report's "Best Hospitals" rankings in Florida and contributing more than $2 billion annually to Florida's economy. In 1986, Mayo Clinic brought its team approach to health care from Rochester, Minnesota, to the Southeast when it opened the clinic… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 12, 2021 Category: Research Source Type: news

Expert Alert: Advancing individualized medicine through genomics
ROCHESTER, Minn. – The virtual 10th Annual Individualizing Medicine Conference on Oct. 8 –9 will highlight the latest discoveries, diagnostics, therapeutics and emerging approaches in the field of genomics. Attendees will hear from renowned experts and learn first-hand how individualized medicine is transforming clinical practice, research and education. Highlighted topics will includ e artificial intelligence, health disparities, precision oncology, microbiome, genomic clinical applications and challenges, and many others. Taking the virtual center stage will be keynote speakers Gianrico… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 7, 2021 Category: Research Source Type: news

Mayo Clinic leads biorepository core for new nationwide research on long-term symptoms of COVID-19
Mayo Clinic research is dedicated to finding solutions for patients who were infected with COVID-19 and the many affected by the long-term symptoms of COVID-19 ― what the National Institutes of Health (NIH) refers to as "long COVID" or post-acute sequelae. In response to great unmet patient need, the NIH launched a new research initiative to understand why some people who were infected with COVID-19 don't fully recover, or develop new or returning sympto ms after… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - September 20, 2021 Category: Research Source Type: news

Science Saturday: A fountain of youth for aging muscles
Regenerative medicine could hold the keys to rejuvenating older muscles, and research supporting that will be featured at the Mayo Clinic Symposium on Regenerative Medicine and Surgery. Preclinical research by Helen Blau, Ph.D., Stanford University School of Medicine, discovered a protein that triggers muscle loss and a way to block it to restore youthful muscle strength. Dr. Blau, director of the Baxter Laboratory for Stem Cell Biology at Stanford University School of Medicine, will present her research in a virtual… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - September 18, 2021 Category: Research Source Type: news