Mayo Clinic study puts price tag on cost of menopause symptoms for women in the workplace
JACKSONVILLE, Fla. — Menopause-related symptoms such as hot flashes, night sweats, mood changes, sleep disturbances, joint aches and cognitive difficulties damage the quality of life for millions of women. They also can adversely affect women in the workplace. A newly published Mayo Clinic study puts numbers on that cost: an estimated $1.8 billion in lost work time per year and $26.6 billion annually when medical expenses are added, in the U.S. alone. "The takeaway for… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 26, 2023 Category: Research Source Type: news
Science Saturday: COVID-19 -- the pandemic that's forever changed laboratory testing
Like many people throughout the world, Matthew Binnicker, Ph.D., remembers exactly where he was and what he was doing when COVID-19 was classified as a pandemic. “Those first few months of the pandemic will be forever ingrained in my memory,” he says. For Dr. Binnicker, director of Mayo Clinic’s Clinical Virology Laboratory, two important dates stand out above the rest. “One was Feb. 17, 2020, when Dr. (William) Morice and I were talking about whether the department should… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 15, 2023 Category: Research Source Type: news
Science Saturday: New standards and open access can help natural language processing
Clinical notes in medical records are rich sources of data about human health. But tapping them for medical research can be challenging because these data come from various sources — and they all look different. "There's no standardization in how data is organized and classified across medical records systems," says Sunyang Fu, Ph.D., a Mayo Clinic biomedical informatics researcher. Even the language people use to talk about health can insert discrepancies in how data are… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 18, 2023 Category: Research Source Type: news
'Deaths of Despair' contribute to 17% rise in Minnesota's death rate during COVID-19 pandemic
ROCHESTER, Minn. — According to a new study published by Mayo Clinic researchers, the COVID-19 pandemic was linked to a 17% increase in the death rate in Minnesota during the first year of the pandemic compared to the two previous years. Deaths were driven by both COVID-19 and other causes linked with preventable "deaths of despair," such as overdose, alcohol use and malnutrition. The study analyzed Minnesota death certificate data available through the Rochester Epidemiology… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 13, 2023 Category: Research Source Type: news
Science Saturday: Researchers elucidate details about the role of inflammation in liver regeneration
The liver has the greatest regenerative capacity of any organ in the body, making it possible for surgeons to treat cancerous and noncancerous diseases with extensive surgical approaches. However, underlying chronic liver diseases, like cirrhosis or nonalcoholic steatohepatitis, are known to inhibit the liver's ability to regenerate after surgery. Without regeneration, the liver cannot function, and patients can develop postoperative liver failure — often a lethal complication. In a recent paper published in JHEP Reports, Mayo… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 4, 2023 Category: Research Source Type: news
Obesity makes it harder to diagnose and treat heart disease
ROCHESTER, Minn. — Being overweight impacts your heart health in more ways than you might think. A new JACC review paper from Mayo Clinic outlines how obesity affects the common tests used to diagnose heart disease and impacts treatments. Cardiovascular disease is the leading cause of death in the U.S. and globall y, yet it is largely preventable. "Excess fat acts as a kind of filter and can skew test readings to under-or overdiagnosis," says senior… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 28, 2023 Category: Research Source Type: news
Mayo Clinic discovery leads to life-changing treatment for young girl with ultra-rare disease
Rare Disease Day on Feb. 28 raises awareness of the 30 million people in the U.S. who have a rare disease. Months after young Maggie Carmichael started taking an experimental drug for her ultra-rare genetic disease, she was able to trade in her wheelchair for a walker. The 9-year-old Mayo Clinic patient even took a few of her first-ever steps on her own. She also became better at feeding herself, her speech improved and she… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 28, 2023 Category: Research Source Type: news
Science Saturday: Could antidepressants cause treatment-emergent mania?
In a study published in Molecular Psychiatry, Mark Frye, M.D., a Mayo Clinic researcher and collaborators, investigated the risk of treatment-emergent mania in bipolar disorder when treated with antidepressants. "We found that antidepressants that increase mitochondrial energetics (cells that extract energy from nutrients for sustaining life) may elevate the risk of treatment-emergent mania," says Dr. Frye. The increased energy expenditure of mania associated with impulsivity, poor judgment, psychosis and loss of insight can drive high-risk behaviors, often… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 25, 2023 Category: Research Source Type: news
Science Saturday: Cross-laboratory collaboration accelerates gold-standard SRA testing
At Mayo Clinic Laboratories, where teamwork powers innovation, a cross-laboratory collaboration has enabled implementation of a cutting-edge, gold standard test for a life-threatening condition known as HIT, or heparin-induced thrombocytopenia. The test, a serotonin release assay (SRA), uses the expertise and technologies of the Special Coagulation Laboratory (SCL) and Clinical Mass Spectrometry Laboratory (CMSL) to guide physicians on making an accurate diagnosis of HIT, which is an important first step in choosing the best blood… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 4, 2023 Category: Research Source Type: news
Mayo Clinic to lead new radiotracer trial for detecting pancreatic cancer
ROCHESTER, Minn. — In an academic-industrial collaboration, Mayo Clinic is assessing in a clinical trial a new radiotracer in pancreatic cancer imaging. As part of the investigation, the new agent, 68Ga-Fibroblast-Activation-Protein-Inhibitors (FAPI)-46 (68Ga-FAPI-46), will be compared with 18-fluorodeoxyglucose ( FDG), which is the current standard-of-care radiotracer, in positron emission tomography (PET) imaging of pancreatic cancer. "The research will focus on pancreatic cancer and evaluate whether this radiotracer does what it's supposed to do, and whether it… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 30, 2023 Category: Research Source Type: news
Science Saturday: Mayo researchers streamline genetic testing in heart failure clinic, improve clinical care
In a new study published in Genetics in Medicine, Mayo Clinic researchers streamlined genetic testing and counseling for patients with dilated cardiomyopathy, a type of heart muscle disease that causes the heart chambers (ventricles) to thin and stretch, growing larger. "We showed that this practice intervention increased t he uptake and yield of genetic testing and counseling in our Heart Failure Clinic," says Naveen Pereira, M.D., a Mayo Clinic cardiologist and senior author of the study. "This may have… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 28, 2023 Category: Research Source Type: news
Science Saturday: Engineering tissue to strengthen underdeveloped hearts
Could cells taken from a small patch of skin become heart muscle and repair a rare congenital heart defect? It's a scientific question that Timothy Nelson, M.D., Ph.D., and collaborators hope to answer for those born with an underdeveloped left heart chamber — a rare, complex condition known as hypoplastic left heart syndrome (HLHS). Discovering the first cell-based therapy to rebuild heart tissue for HLHS has been a decade-long r esearch passion for Dr. Nelson, who is the director… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 21, 2023 Category: Research Source Type: news
Mayo Clinic researchers identify women with twice the risk of cancer in both breasts
ROCHESTER, Minn. — Women with cancer in one breast may be at higher risk of developing cancer in the opposite breast if they are carriers of specific genetic changes that predispose them to develop breast cancer, according to a study led by the Mayo Clinic Comprehensive Cancer Center. The findings, published in th e Journal of Clinical Oncology, will help personalize approaches to breast cancer screening and risk factors, study authors say. The study used data… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 19, 2023 Category: Research Source Type: news
Science Saturday: MayoComplete next-generation sequencing -- Transforming comprehensive cancer care
For patients facing a cancer journey, navigating diagnosis and treatment can be extremely daunting. Fear of the unknown is compounded by a confusing ocean of emerging information on discoveries and technological advancements. While each wave of progress brings about new types of treatment, including targeted and immune therapies linked to improved outcomes, the cancer ’s nuances must be understood for these pioneering treatments to work. Laboratory testing offers crucial information to help patients traverse the shifting… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 7, 2023 Category: Research Source Type: news
Science Saturday: Aspiring to deliver new cures for complex conditions
Mayo Clinic is building toward a future when biologics can cure cancer, kidney disease and diabetes. Mayo marks 2022 as a year of significant strides in accelerating science to make and deliver regenerative biotherapeutics. The goal is to offer new options, based on rigorous research in cell and gene therapies, for disorders with few available treatments. The Mayo Clinic Center for Regenerative Biotherapeutics has a new strategy of advancing regenerative discoveries toward early-stage clinical trials and industry… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 31, 2022 Category: Research Source Type: news
