Socioeconomic status measure helps researchers develop artificial intelligence models, improving equity in health care
Social determinants of health impact people ’s well-being and quality of life. These social determinants — conditions such as access to nutrition, safe and affordable housing, jobs, transportation, and access to health care — are some of the factors that lead to disparities in health and health care if they are not addressed. "Defining and assessing social determinants of health really invites clinicians, educators, and researchers to embrace a broader understanding of health in the social… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 28, 2022 Category: Research Source Type: news
NIH's All of Us Research Program returns health-related DNA results to participants
The National Institutes of Health's (NIH) All of Us Research Program has begun returning personalized health-related DNA results to more than 155,000 participants. The reports detail whether participants have an increased risk for specific health conditions and how their bodies might process certain medications. The All of Us Research Program collects participants' blood, urine, and saliva samples. These biosamples are stored and managed for research at a specialized All of Us Research Program biobank at Mayo Clinic. "It is rewarding for us at the… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 19, 2022 Category: Research Source Type: news
Science Saturday: Researchers investigate precision nutrition to improve health, prevent diseases
Could prescribing specific nutrients, grains, fruits and vegetables tailored to a person's DNA and other biological characteristics help improve their health? Precision nutrition took center stage at Mayo Clinic's Individualizing Medicine Conference Nov. 2 –3, 2022, in Rochester, Minnesota, where some of the world’s top experts shared their knowledge of the potential benefits of tailoring nutrients and dietary guidance to a person's genes, metabolism, microbiome and other distinguishing characteristics. The ultimate goal of the holistic approach i s to… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 17, 2022 Category: Research Source Type: news
Science Saturday: A preclinical step toward treating chronic dry mouth
Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. "The team was satisfied to see a 50% reduction in chronic salivary function with radiation in mice — our first and major… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 3, 2022 Category: Research Source Type: news
Real-world evidence study of regenerative medicine and shoulder surgery
Applying regenerative medicine to a common shoulder surgery could have an impact on the need for follow-up revision surgery in some patients, according to a Mayo Clinic study of real-world evidence.Mayo Clinic researchers analyzed the largest set of data available to determine if adding bone marrow aspirate concentrate to repaired tissue after standard rotator cuff surgery would improve outcomes for patients. Bone marrow aspirate is fluid taken from a patient's bone marrow that contains concentrated growth factors,… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 16, 2022 Category: Research Source Type: news
AI transforms smartwatch ECG signals into a diagnostic tool for heart failure
Two health tech advances are at the heart of a study published in Nature Medicine: an app and backend infrastructure to let patients remotely share smartwatch ECG data with their clinicians in an easy and secure way, and the modification of a proven 12-lead ECG artificial intelligence (AI) algorithm to enable it to run on a single-lead watch ECG recording. An AI algorithm applied to Apple Watch ECG recordings successfully identified a weak heart pump… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 14, 2022 Category: Research Source Type: news
Science Saturday: Seeking a cellular therapy for chronic kidney disease
Every year, more than 130,000 people in the U.S. are diagnosed with end-stage kidney disease, with most cases caused by diabetes. Newer therapies show promise to slow kidney failure rates, but none stop progression to end-stage kidney failure. The research goal of LaTonya Hickson, M.D., is to develop a cell-based therapy that slows — or even stops — diabetic kidney disease from advancing to end-stage kidney disease. "It is going to take a multipronged approach. By utilizing… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 12, 2022 Category: Research Source Type: news
Beating the odds for a transplant
When the phone rang in the middle of a Sunday night news program, and the caller ID flashed Mayo Clinic, Dennis Pinkerton and his wife, Rhonda, knew it was a pivotal moment. The doctor on the line delivered news he thought he'd never hear. A pair of donor lungs — kept alive and breathing on a high-tech machine — were a perfect match. "It felt like a miracle. I live only about 10 minutes from… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 10, 2022 Category: Research Source Type: news
Science Saturday: AI enables early identification, intervention in debilitating lung disease
In a new study published in Nature Medicine, Mayo Clinic and several research collaborators from across the U.S., describe a successful new artificial intelligence, or AI, -enabled tool to identify idiopathic pulmonary fibrosis, also called IPF, before patients have recognizable symptoms. This tool could alert a patient's primary care team of a probable IPF diagnosis based on comorbidities and risk scores. The tool should prompt earlier referral to pulmonary specialty care to confirm the diagnosis with CT scanning… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 29, 2022 Category: Research Source Type: news
Trailblazing scientists discuss exposome research, precision nutrition at Mayo Clinic's Individualizing Medicine Conference
ROCHESTER, Minn. — The next frontier in individualized medicine is here. Mayo Clinic's 11th annual Individualizing Medicine Conference on Nov. 2–3 will focus on "Exploring the Exposome" — the cumulative measure of environmental influences and associated biological responses throughout the life span of a person , and how those exposures relate to health and disease. "We've made significant progress in mapping the human genome and understanding the role of genes in diseases, but genetics only accounts… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 25, 2022 Category: Research Source Type: news
A History of Cancer, Coronary Artery Disease May Reduce Risk of Dementia
The risks of dementia, cancer and vascular disease increase with age, but the connection between the conditions is not fully understood. Now, Mayo Clinic researchers report an intriguing finding: Having a history of cancer or coronary artery disease may actually reduce the risk of dementia. Their study results are published in the Journal of Alzheimer's Disease. People 85 and older are the fastest growing segment in the U.S., with the percentage of those in that age bracket expected to more than double… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 24, 2022 Category: Research Source Type: news
Mayo Clinic Minute: Flu vaccine may reduce risk of stroke
Getting a flu shot may offer an added benefit. A recent study published in Stroke, an American Heart Association journal, suggests flu vaccination might lower the chances of stroke among adults, especially people under 45. Dr. Gyanendra Kumar, a Mayo Clinic neurologist not involved in the study, says it's long been known that respiratory infections increase the risk of stroke in the days following infection. Watch: The Mayo Clinic Minute https://youtu.be/RuTvvyd_A24 Journalists: Broadcast-quality video pkg (1:00) is in the downloads at the end of the… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 24, 2022 Category: Research Source Type: news
AI-guided screening uses ECG data to detect a hidden risk factor for stroke
An AI-guided targeted screening strategy is effective in detecting new cases of atrial fibrillation that would not have come to attention in routine clinical care. This strategy could reduce the number of undiagnosed cases of atrial fibrillation, and prevent stroke and death in millions of patients across the globe. ROCHESTER, Minn. — Researchers at Mayo Clinic used artificial intelligence (AI) to evaluate patients’ electrocardiograms (ECGs) in a targeted strategy to screen for atrial fibrillation, a… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - September 28, 2022 Category: Research Source Type: news
Mayo Clinic Minute: What is a Hispanic biobank?
A growing number of people in the U.S. identify as Hispanic. That has the medical community looking closer at diversifying information and samples that can apply to a broader patient population. Dr. Richard O. White, a Mayo Clinic community internal medicine physician, says biobanks, including the Jax Saludable Biobank, are shaping the future of medicine. Watch: The Mayo Clinic Minute https://www.youtube.com/watch?v=pyeUa_pBxmQ&feature=youtu.be Journalists: Broadcast-quality video pkg (1:00) is in the downloads at the end of the post. Please… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - September 22, 2022 Category: Research Source Type: news
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
ROCHESTER, Minn. — In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. Liewei Wang, M.D., Ph.D. "We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong survival," says Liewei Wang, M.D., Ph.D., the Bernard and Edith Waterman Director, Pharmacogenomics… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - September 22, 2022 Category: Research Source Type: news
