Big data adds clarity, certainty to clinical trial outcomes for AFib
ROCHESTER, Minn. -- The 33 million people with atrial fibrillation worldwide not only suffer from bothersome symptoms, but also face a fivefold increased risk of stroke and a twofold increased risk of death. Research teams led by Mayo Clinic published three connected studies on Friday, March 15, clarifying the benefits of catheter ablation versus rate- [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 14, 2019 Category: Research Source Type: news
Mayo Clinic study shows sleep apnea may be tied to increased Alzheimer's biomarker in brain
ROCHESTER, Minn. -- People who stop breathing during sleep may have higher accumulations of the toxic protein tau, a biological hallmark of Alzheimer's disease, in part of the brain that manages memory, navigation and perception of time. A preliminary Mayo Clinic study released Sunday, March 3, will be presented at the American Academy of Neurology's [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 3, 2019 Category: Research Source Type: news
Science Saturday: Leading the charge in regenerative medicine
Regenerative medicine therapies aim to rebuild and restore health to patients challenged by chronic conditions and degenerative diseases. Despite advances in the field, much of the science is still in early research phases, meaning that many treatments haven't been proven safe and effective for humans as standard-of-care therapies yet. Because the scientific process is long, [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 1, 2019 Category: Research Source Type: news
Research finds ethnoracial differences in Alzheimer's disease
JACKSONVILLE, Fla -- A team of Mayo Clinic researchers found Hispanic-American patients with Alzheimer's tend to survive significantly longer with the disease than other ethnoracial groups, according to a study in Alzheimer's& Dementia: The Journal of the Alzheimer's Association. Hispanic-Americans were found to live an average of 12 years with the disease from the [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 18, 2019 Category: Research Source Type: news
Science Saturday: Bitten by the virotherapy bug
Every day more than 1,600 Americans die from cancer. Most?of them have cancer that can't be cured with traditional?methods -- surgery, radiation and chemotherapy. The father?of?Evanthia Galanis, M.D., was one of them. He died in the late 1990s from?melanoma?when his daughter was?a junior faculty member at?Mayo Clinic. "My father would have better treatment options today," [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 16, 2019 Category: Research Source Type: news
Science Saturday: Brain organoids and neuropsychiatric disorders
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic's team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 19, 2019 Category: Research Source Type: news
Mayo Clinic discovers biological markers that could guide treatment for prostate cancer
ROCHESTER, Minn. ? Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, Mayo Clinic has discovered. The research, which is published in the January edition of Mayo Clinic Proceedings, found for the first time that genetic alterations associated with intermediate- and high-risk prostate [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 3, 2019 Category: Research Source Type: news
Obese mice lose anxiety when 'zombie cells' exit their brain
ROCHESTER, Minn. ? Mayo Clinic researchers and collaborators have shown in mice that obesity increases the level of "zombie" or senescent cells in the brain, and that those cells, in turn, are linked to anxiety. When senolytic drugs are used to clear those cells, the anxious behaviors in the mice dissipate. These findings appear in [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 3, 2019 Category: Research Source Type: news
Science Saturday: Discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,? researchers at the?Mayo Clinic Center for Individualized Medicine? have discovered. The?research?is published in the?Journal of Thoracic Oncology. ?What we?ve shown so far is that these large complex chromosomal rearrangements are frequent in mesothelioma and may provide [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 15, 2018 Category: Research Source Type: news
Sharing Mayo Clinic: An active life restored, thanks to regenerative medicine
For years, Rick Amatuzio lived with severe back pain that kept him from the active life he'd always savored. But advanced diagnostic tests and regenerative medicine therapy at Mayo Clinic ultimately led to a complete recovery. Now Rick once again can play sports and enjoy the outdoors free from pain.? ? A typical weekend for [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 9, 2018 Category: Research Source Type: news
Oxybutynin lessens hot flash frequency, improves breast cancer survivor quality of life, Mayo-led study finds
SAN ANTONIO ? Research led by oncologists Roberto Leon-Ferre, M.D. and Charles Loprinzi, M.D. of Mayo Clinic has found that the drug oxybutynin helps to reduce the frequency and intensity of hot flashes in women who are unable to take hormone replacement therapy, including breast cancer survivors. These findings were presented at the 2018 San [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 7, 2018 Category: Research Source Type: news
Science Saturday: Potential and pitfalls of gene therapy
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 1, 2018 Category: Research Source Type: news
Father's disease inspires son's journey to find a cure
It's amazing how far some people will go to accomplish their dream. Dr. Fouad Chebib grew up in a small town in Lebanon. After finishing medical school in Lebanon's capital city, Beirut, Dr. Chebib chased his dream across the world to Mayo Clinic in Rochester, Minnesota. "I'm one of the kidney doctors," Dr. Chebib says. [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 21, 2018 Category: Research Source Type: news
Science Saturday: Novel data-driven approach for precision medicine
Thousands of patients? tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 17, 2018 Category: Research Source Type: news
Science Saturday: Brainstorming on epilepsy
Epilepsy strikes without warning, when an electrical storm sweeps across the brain. Storm-chasing teams of researchers have adopted computational techniques to pinpoint and predict seizure activity.?? Where exactly does a seizure originate? How can the onset of a seizure be predicted? The emerging answers to these mysteries have two things in common: epilepsy, one of [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 3, 2018 Category: Research Source Type: news
