Science Saturday: Using metal detectors to ward off wayward specimens
The Histology Laboratory in Mayo Clinic’s Department of Laboratory Medicine and Pathology processes more than 350,000 paraffin-embedded blocks every year as lab staff prepare tissue slides for pathologists to evaluate. Each of those blocks represents a patient waiting for answers. Although lost s pecimens within the Histology Lab are rare — less than one-half of 1% are ever misplaced — if even one specimen goes missing, it has the potential to be devastating for that patient. "We're aiming for zero.… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - May 14, 2022 Category: Research Source Type: news
Researchers seek to improve success of chimeric antigen receptor-T cell therapy in non-Hodgkin lymphoma
JACKSONVILLE, Fla. — A study published by researchers from Mayo Clinic Cancer Center at Mayo Clinic in Florida and Case Western, Cleveland Medical Center, investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma treated with chimeric antigen receptor-T cell therapy (CAR-T cell t herapy). The study is published in Cancer Discovery. "CAR-T cell therapy is a promising treatment for non-Hodgkin lymphoma, especially for patients who have relapsed or those who have not responded… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - May 12, 2022 Category: Research Source Type: news
Science Saturday: What you should know about genetics, colorectal cancer
Colorectal cancer begins when healthy cells in the colon or rectum develop mutations, or changes, in their DNA. These damaged cells then become cancerous, grow and divide uncontrollably, and form a tumor. Genetic factors play a role in this process. Some gene mutations passed through generations of your family can increase your risk of colorectal cancer significantly. The most common inherited syndromes that increase colorectal cancer risk are familial adenomatous polyposis and Lynch syndrome, also known as hereditary… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - May 7, 2022 Category: Research Source Type: news
Science Saturday: Uncovering disparities in local communities -- the case of the HPV vaccine
Where you live may affect whether you receive the cancer-preventing HPV vaccine, suggests a new study published in the journal Vaccine. The first human papillomavirus (HPV) vaccine was approved for use in the U.S. by the Food and Drug Administration in 2006. According to the National Cancer Institute, the types of HPV the current vaccine covers are those which cause 90% of genital warts, as many as 90% of cervical cancers, as well as a majority of oropharyngeal (a type of throat cancer), anal, penile, vaginal and vulvar cancers.… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 30, 2022 Category: Research Source Type: news
Expert Alert: Laser therapy brings the heat to minimally invasive epilepsy treatment
ROCHESTER, Minn. — For roughly one-third of people with epilepsy, medication does not control their seizures. Depending on where seizures originate in the brain, laser interstitial thermal therapy (LITT) may be a minimally invasive surgery option. As the name suggests, lasers are used to increase the temperature o f the tissue to disable a small portion of brain tissue. Real-time MRI monitoring helps the surgeon and radiology team pinpoint the treatment while protecting other important areas of the brain. … (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 29, 2022 Category: Research Source Type: news
Mayo Clinic study confirms living kidney donor surgery is low risk for most patients
ROCHESTER, Minn. — The risk of major complications for people who donate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year Mayo Clinic study of more than 3,000 living kidney donors. Only 2.5% of patients in the study experienced major complications, and all recovered completely. "Th e results of this study are extremely reassuring for individuals who are considering being living kidney donors. We found that this lifesaving surgery, when performed… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 25, 2022 Category: Research Source Type: news
Science Saturday: Regenerating damaged vocal cords
Cells from amniotic membrane show potential of repairing vocal cord injuries that don't respond to standard care, Mayo Clinic discovered in preclinical research. The placental membrane provides a rich source of epithelial cells that could regenerate damaged tissue. Research by David Lott, M.D., a laryngeal surgeon in Arizona, found epithelial cells extracted after childbirth triggered healing in animals with vocal cord damage. Dr. Lott's paper is published in Stem Cell Research& Therapy. "We believe our study… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 23, 2022 Category: Research Source Type: news
Mayo researchers, collaborators affirm useful blood biomarker for group of brain disorders in new study
JACKSONVILLE, Fla. — A test of protein in the blood gets further support as a biomarker for patients diagnosed with frontotemporal dementia (FTD), a group of brain disorders with few treatment options. These disorders are characterized by changes in behavior, cognition, language or movement. In a new paper published in Cell Reports Medicine, Mayo Clinic researchers and members of the Advancing Research and Treatment in Frontotemporal Lobar Degeneration and Longitudinal Evaluation of Familial Frontotemporal Dementia… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 19, 2022 Category: Research Source Type: news
AI reduces miss rate of precancerous polyps in colorectal cancer screening
JACKSONVILLE, Fla. — Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers led by Mayo Clinic. The study is published in Gastroenterology. Most colon polyps are harmless, but some over time develop int o colon or rectal cancer, which can be fatal if found in its later stages. Colorectal cancer is the second most deadly cancer in the world, with an estimated… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - April 18, 2022 Category: Research Source Type: news
Science Saturday: Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows
A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections. In response, a team of researchers from Mayo Clinic ’s Center for Individualized Medicine has developed a sequencing technology to rapidly detect and identify microbes and antibiotic-resistant phenotypes in a single test. The innovative nanopore sequencing method is published in Surgery and mSphere,… ...
Source: Mayo Clinic Research News - April 2, 2022 Category: Research Source Type: news
Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes
ROCHESTER, Minn. ― In a newly published study appearing in Genetics in Medicine, investigators from Mayo Clinic and Baylor College of Medicine found that targeted genomic information can play an important role in drug prescribing practices. The results from the "Right Drug, Right Dose, Right Time: Using Genomic Da ta to Individualize Treatment" (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 22, 2022 Category: Research Source Type: news
Science Saturday: From fasting to a pill? Mayo Clinic scientists explore the biology of caloric restriction
New year, same topics: nutrition, healthy eating and slowing the downhill roll of aging. Eat this, not that — never that — and try this one weird thing to look younger, right? Advice spans the spectrum from dubious to scientifically supported, but there is an approach that sidesteps it all: eat less. Either in a specific time frame or in general, limiting calories safely is called caloric restriction, food restriction or fasting. It's not a… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 19, 2022 Category: Research Source Type: news
Senolytic drugs boost key protective protein
This study shows… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 15, 2022 Category: Research Source Type: news
Mayo Clinic launches first national collaborative Limb Loss and Preservation Registry
ROCHESTER, Minn. — Mayo Clinic has received authorization from the Federal Risk and Authorization Management Program to begin operating the Limb Loss and Preservation Registry, a national collaborative warehouse for data on people who have lost limbs and may or may not have access to prosthetics. The registry will be the first of its kind in the U.S. The goal of the Limb Loss and Preservation Registry is to generate knowledge about which advances make a… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - March 8, 2022 Category: Research Source Type: news
Science Saturday: Mayo Clinic develops automated system to accelerate diagnoses for patients with rare diseases
Mayo Clinic researchers are working to accelerate the diagnoses of rare diseases and renew hope for patients whose symptoms have defied an explanation ― sometimes for years or even decades. The team of genomics experts has developed an automated system called RENEW for tracking new scientific knowledge from around the world of pathogenic genetic variants and applying it to Mayo Clinic patients with rare and undiagnosed diseases. RENEW stands for reanalysis of negative whole-exome/genome data. "We're… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - February 26, 2022 Category: Research Source Type: news
