First hybrid gene therapy shows early promise in treating long QT syndrome
ROCHESTER, Minn. ? In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. Researchers demonstrated its potential therapeutic efficacy in two in vitro model systems using beating heart cells reengineered from the blood samples of [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 28, 2021 Category: Research Source Type: news

Science Saturday: A mathematical index to distinguish healthy microbiome
What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 9, 2021 Category: Research Source Type: news

Science Saturday: Conquering cancer by targeting its genetic abnormalities
Joanne Garnett has harrowing memories of that life-changing day back in 1981. She was a 39-year-old land use planner living in Wyoming when she received a call from her doctor confirming she had uterine cancer.  "I was shocked, and it was strange because I didn't fit any profile for uterine cancer," Garnett recalls. "I got a [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 9, 2021 Category: Research Source Type: news

Science Saturday: 10 non-COVID conversation starters for your virtual holiday get-togethers
Holiday gatherings have gone virtual this year, but one thing hasn't changed: the social pressure to find interesting things to say to our relatives. Whether on the phone, or staring blankly at Auntie Carol over Zoom, we all dread that moment of uncomfortable silence. Well fear no more. Everyone likes to talk about their health [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 26, 2020 Category: Research Source Type: news

Will fast-tracked COVID-19 vaccines be safe?
As health care organizations begin planning for distribution of COVID-19 vaccines, many questions are being asked about their safety and efficacy. Dr. Andrew Badley, an infectious diseases physician at Mayo Clinic and head of Mayo Clinic's COVID-19 Research Task Force, offers some insight on how COVID-19 vaccines were fast-tracked to get them ready for the public. Watch: Dr. Andrew Badley [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - December 9, 2020 Category: Research Source Type: news

Consumer Health: What do you know about COPD?
November is National COPD Awareness Month, which makes it a good time learn more about chronic obstructive pulmonary disease (COPD). COPD is the third leading cause of death by disease in the U.S., with more than 16.4 million people living with the disease, according to the American Lung Association. This chronic inflammatory lung disease is caused by [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 13, 2020 Category: Research Source Type: news

Science Saturday: Turning back the clock on aging
Researchers at Mayo Clinic are probing ways to activate the body's regenerative potential to slow the clock on chronic conditions that set in as we age. From cancer to diabetes to Alzheimer's disease, another birthday adds to a person's risk of developing chronic disease. September is Healthy Aging Month, a time to focus on the positive aspects of aging. Mayo Clinic Center [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 31, 2020 Category: Research Source Type: news

Toxic cellular ooze linked to biological age, disease and disability
Cells in the body usually do what they're told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body's order to expire: senescent cells. Sometimes called "zombie cells" for their undead lingering, senescent cells have triggered the body's kill command, but instead [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 30, 2020 Category: Research Source Type: news

Mayo Clinic Q & amp;A podcast: Digital tools help Mayo Clinic with contact tracing
As positive cases of COVID-19 continue to spike across much of the country, the role of contact tracing to prevent further spread becomes more important. Contact tracing is the process of notifying people who have had close contact with people newly infected with COVID-19, to let them know they may have been exposed. When it [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 29, 2020 Category: Research Source Type: news

Science Saturday: Seeing cancer, but not through a microscope
Toward the end of the 19th century, a French doctor named Ernest Besnier coined the term "biopsy," combining the Greek bios (life) and opsis (a sight). In the decades since, clinicians have performed countless biopsies on suspected cancer patients, all to catch a glimpse of cells on the brink of growing out of control. This [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 24, 2020 Category: Research Source Type: news

Science Saturday: Mining the molecular origins of breast cancer for new cures
October is Breast Cancer Awareness Month, a time to focus on new strategies for prevention and early detection. Mayo Clinic Center for Regenerative Medicine and Mayo Clinic Cancer Center support stem cell biology research to uncover the molecular origins of breast cancer in order to bring new cures to the practice. Answering what are the causes of breast cancer at [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 17, 2020 Category: Research Source Type: news

Women's Wellness: Uterine fibroids are common noncancerous growths
Uterine fibroids are noncancerous growths of the uterus that often appear during childbearing years. Also called leiomyomas (lie-o-my-O-muhs) or myomas, uterine fibroids aren't associated with an increased risk of uterine cancer and almost never develop into cancer. Fibroids range in size from seedlings, undetectable by the human eye, to bulky masses that can distort and [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 16, 2020 Category: Research Source Type: news

Alzheimer's book offers updated resource for patients, care partners
ROCHESTER, Minn. -- Misplacing keys, forgetting the way to a doctor's appointment, trouble recalling a neighbor's name: Are these examples of typical aging? What's the difference between Alzheimer's disease and other forms of dementia? What's actually happening to the brain, and how can you keep it healthy? The second edition "Mayo Clinic on Alzheimer's Disease [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 13, 2020 Category: Research Source Type: news

Science Saturday: Vaccines 101 - The Basics, and COVID-19
Vaccine stories are all around as the world waits for news on the many COVID-19 vaccines working their way through testing. Robert Jacobson, M.D., a Mayo Clinic pediatrician and nationally regarded expert in the delivery of vaccines for children, discusses here the basics of vaccines, making connections from history to the COVID-19 pandemic in a presentation [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 10, 2020 Category: Research Source Type: news

Research of Experimental COVID-19 Therapeutics Explained
As is clear after months of the pandemic, COVID-19 can affect people in a number of ways. Some can be infected and have no symptoms ? what's known as asymptomatic. Others have symptoms, but do not have a serious illness. A third category, however, can require hospitalization for intensive complications. For those with symptoms or [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 4, 2020 Category: Research Source Type: news