The effects of Lavandula angustifolia essential oil on analgesic effects and percutaneous absorption of naproxen sodium gel; an in vivo and in vitro study
This article is protected by copyright. All rights reserved.PMID:36573522 | DOI:10.1111/1440-1681.13747 (Source: Clinical and Experimental Pharmacology and Physiology)
Source: Clinical and Experimental Pharmacology and Physiology - December 27, 2022 Category: Drugs & Pharmacology Authors: Seyyed Sohrab Rostamkalaei Maryam Iman Ramin Ataee Zahra Bahari Source Type: research
Naproxen sodium nanoparticles are less toxic and gastroprotective agents than the conventional NSAID drug naproxen sodium in Balb/c mice
Toxicol Appl Pharmacol. 2022 Aug 8:116192. doi: 10.1016/j.taap.2022.116192. Online ahead of print.ABSTRACTUse of non-steroidal anti-inflammatory drugs (NSAIDs) is one of the leading causes of gastric ulcers. Excellent therapeutic properties have made the use of NSAIDs widespread. Nano-drug delivery to reduce systemic toxicity through modulating drug pharmacokinetics may be a better choice. Presently, we investigated if naproxen nanoformulation (PVA capped NPRS-MgO NPs) is less toxic to be used as an alternative drug. Groups of mice were assigned to control, NPRS-treated, CNF-treated, UNF-treated, and MgO NPs-treated groups...
Source: Toxicology and Applied Pharmacology - August 11, 2022 Category: Toxicology Authors: Ayesha Razzaq Irfan Zia Qureshi Source Type: research
Naproxen sodium nanoparticles are less toxic and gastroprotective agents than the conventional NSAID drug naproxen sodium in Balb/c mice
Toxicol Appl Pharmacol. 2022 Aug 8:116192. doi: 10.1016/j.taap.2022.116192. Online ahead of print.ABSTRACTUse of non-steroidal anti-inflammatory drugs (NSAIDs) is one of the leading causes of gastric ulcers. Excellent therapeutic properties have made the use of NSAIDs widespread. Nano-drug delivery to reduce systemic toxicity through modulating drug pharmacokinetics may be a better choice. Presently, we investigated if naproxen nanoformulation (PVA capped NPRS-MgO NPs) is less toxic to be used as an alternative drug. Groups of mice were assigned to control, NPRS-treated, CNF-treated, UNF-treated, and MgO NPs-treated groups...
Source: Toxicology and Applied Pharmacology - August 11, 2022 Category: Toxicology Authors: Ayesha Razzaq Irfan Zia Qureshi Source Type: research
Analgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial
CONCLUSION: In moderate-to-severe postsurgical dental pain, a single dose of NapS was at least as effective as HYD+APAP in the early hours, significantly more effective at reducing pain intensity and providing greater pain relief over 12 hours, and was better tolerated. When not contraindicated, NapS should be considered a preferred alternative to opioid combinations for acute pain. (ClinicalTrials.gov, Identifier: NCT04307940; https://clinicaltrials.gov/ct2/show/NCT04307940).PMID:34878953 | DOI:10.1080/00325481.2021.2008180 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - December 8, 2021 Category: Internal Medicine Authors: Stephen A Cooper Paul J Desjardins Todd Bertoch Alberto Paredes-Diaz Emanuel Troullos Azita Tajaddini Robert Centofanti Robert An Donna Morella Source Type: research
Use of naproxen versus intracervical block for pain control during the 52-mg levonorgestrel-releasing intrauterine system insertion in young women: a multivariate analysis of a randomized controlled trial
To compare the effectiveness of 550 mg naproxen sodium versus 6 mL 2%-lidocaine intracervical block in pain lowering at the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) placement in young women. (Source: BMC Women's Health)
Source: BMC Women's Health - October 29, 2021 Category: OBGYN Authors: Elaine Cristina Fontes de Oliveira, Tha ís Baêta, Ana Paula Caldeira Brant, Agnaldo Silva-Filho and Ana Luiza Lunardi Rocha Tags: Research Source Type: research
Analgesic Efficacy of Etoricoxib following Third Molar Surgery: A Meta-analysis
CONCLUSION: Etoricoxib significantly reduces the number of patients needing rescue analgesics compared to NSAIDs after third molar surgery.PMID:34539935 | PMC:PMC8445708 | DOI:10.1155/2021/9536054 (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 20, 2021 Category: Neurology Authors: Lorenzo Franco-de la Torre Diana Laura Franco-Gonz ález Lorena Michele Brennan-Bourdon Nelly Molina-Frechero Ángel Josabad Alonso-Castro Mario Alberto Isiordia-Espinoza Source Type: research
Analgesic Efficacy of Etoricoxib following Third Molar Surgery: A Meta-analysis
CONCLUSION: Etoricoxib significantly reduces the number of patients needing rescue analgesics compared to NSAIDs after third molar surgery.PMID:34539935 | PMC:PMC8445708 | DOI:10.1155/2021/9536054 (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 20, 2021 Category: Neurology Authors: Lorenzo Franco-de la Torre Diana Laura Franco-Gonz ález Lorena Michele Brennan-Bourdon Nelly Molina-Frechero Ángel Josabad Alonso-Castro Mario Alberto Isiordia-Espinoza Source Type: research
Analgesic Efficacy of Etoricoxib following Third Molar Surgery: A Meta-analysis
CONCLUSION: Etoricoxib significantly reduces the number of patients needing rescue analgesics compared to NSAIDs after third molar surgery.PMID:34539935 | PMC:PMC8445708 | DOI:10.1155/2021/9536054 (Source: Behavioural Neurology)
Source: Behavioural Neurology - September 20, 2021 Category: Neurology Authors: Lorenzo Franco-de la Torre Diana Laura Franco-Gonz ález Lorena Michele Brennan-Bourdon Nelly Molina-Frechero Ángel Josabad Alonso-Castro Mario Alberto Isiordia-Espinoza Source Type: research
Exploration of nanoethosomal transgel of naproxen sodium for the treatment of Arthritis.
CONCLUSION: The ethosomal gel was successfully developed and has shown the potential to be a good replacement option for the conventional therapies of rheumatoid arthritis.
PMID: 32713340 [PubMed - as supplied by publisher] (Source: Current Drug Delivery)
Source: Current Drug Delivery - July 23, 2020 Category: Drugs & Pharmacology Authors: Anjum F, Zakir F, Verma D, Aqil M, Singh M, Jain P, Mirza MA, Anwer MK, Iqbal Z Tags: Curr Drug Deliv Source Type: research
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Publication date: Available online 16 July 2020Source: International Journal of PharmaceuticsAuthor(s): Hiroshi Ueda, Johan Peter Bøtker, Magnus Edinger, Korbinian Löbmann, Holger Grohganz, Anette Müllertz, Thomas Rades, Jesper Østergaard (Source: International Journal of Pharmaceutics)
Source: International Journal of Pharmaceutics - July 17, 2020 Category: Drugs & Pharmacology Source Type: research
Preparation and characterization of hydrophobic stearic acid-Yb-PbO2 anode and its application on the electrochemical degradation of naproxen sodium
Publication date: Available online 1 May 2020Source: Journal of Electroanalytical ChemistryAuthor(s): Yang Yang, Yun Xia, Feng Wei, Ganggang Teng, Yingwu Yao (Source: Journal of Electroanalytical Chemistry)
Source: Journal of Electroanalytical Chemistry - May 2, 2020 Category: Chemistry Source Type: research
Pharmacokinetic linearity of naproxen and efficacy of naproxen sodium at various doses
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CONCLUSION: The pharmacokinetic linearity associated with NAP means that data on efficacy for the lower OTC doses of NAPSO can be extrapolated to the higher OTC doses. Thus, it is given that NAPSO 275 and 550 mg will be at least as effective as or superior to the lower doses of 220 and 440 mg.
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PMID: 32324130 [PubMed - as supplied by publisher] (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - April 24, 2020 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research
Influence of microwave drying and conventional drying methods on the mechanical properties of naproxen sodium drug tablets
Publication date: Available online 1 April 2020Source: ParticuologyAuthor(s): Maha Al-Ali, Rajarathinam Parthasarathy (Source: Particuology)
Source: Particuology - April 2, 2020 Category: Science Source Type: research
An Experimental Comparison of the Analgesic and Anti-Inflammatory Effects of Safflower Oil, Benzydamine HCl, and Naproxen Sodium
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - March 26, 2020 Category: Nutrition Authors: Ali Alaiye Ercan Kaya Mehmet Özgür Pınarbaşlı Nu şin Harmancı Cafer Y ıldırım Dilek Buruko ğlu Dönmez Cemal Cingi Source Type: research
