Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021
This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. De...
Source: MMWR Recomm Rep - January 3, 2022 Category: Epidemiology Authors: Gabriela Paz-Bailey Laura Adams Joshua M Wong Katherine A Poehling Wilbur H Chen Veronica McNally Robert L Atmar Stephen H Waterman Source Type: research
Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021
This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. De...
Source: MMWR Recomm Rep - January 3, 2022 Category: Epidemiology Authors: Gabriela Paz-Bailey Laura Adams Joshua M Wong Katherine A Poehling Wilbur H Chen Veronica McNally Robert L Atmar Stephen H Waterman Source Type: research
Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021
This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. De...
Source: MMWR Recomm Rep - January 3, 2022 Category: Epidemiology Authors: Gabriela Paz-Bailey Laura Adams Joshua M Wong Katherine A Poehling Wilbur H Chen Veronica McNally Robert L Atmar Stephen H Waterman Source Type: research
Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021
This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. De...
Source: MMWR Recomm Rep - January 3, 2022 Category: Epidemiology Authors: Gabriela Paz-Bailey Laura Adams Joshua M Wong Katherine A Poehling Wilbur H Chen Veronica McNally Robert L Atmar Stephen H Waterman Source Type: research
Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021
This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. De...
Source: MMWR Recomm Rep - January 3, 2022 Category: Epidemiology Authors: Gabriela Paz-Bailey Laura Adams Joshua M Wong Katherine A Poehling Wilbur H Chen Veronica McNally Robert L Atmar Stephen H Waterman Source Type: research
Implicit Racial Attitudes and Associations Among Obstetricians in Hawai ʻi: a Pilot Study
ConclusionThe findings from this pilot suggest a slight degree of implicit bias favoring Whites over Micronesians within this sample of OB-GYNs and warrant a larger investigation into implicit biases toward this unique and understudied Pacific Islander population. (Source: Journal of Racial and Ethnic Health Disparities)
Source: Journal of Racial and Ethnic Health Disparities - January 1, 2022 Category: International Medicine & Public Health Source Type: research
Challenges in Eye Care in the Asia-Pacific Region
This article aims to shed light on challenges faced by the Asia-Pacific ophthalmic community and propose corresponding strategies to tackle those challenges. (Source: Asia-Pacific Journal of Ophthalmology)
Source: Asia-Pacific Journal of Ophthalmology - September 1, 2021 Category: Opthalmology Tags: Review Article Source Type: research
Management of Suboptimal Response to Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: Re-induction Therapy or Direct to Radiotherapy?
Nasopharyngeal carcinoma (NPC) is a head and neck cancer highly endemic in southeast Asia (especially South China), Micronesia and Polynesia, eastern Asia, and northern Africa (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - August 25, 2021 Category: Radiology Authors: Ting Liu, Li-Ting Liu, Jie-Yi Lin, Bo-Wen Shen, Shan-Shan Guo, Sai-Lan Liu, Xue-Song Sun, Yu-Jing Liang, Mei-Juan Luo, Xiao-Yun Li, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai Tags: Original Article Source Type: research
HTLV-1 associated acute adult T-cell lymphoma/leukemia presenting as acute liver failure in Micronesian: A case report
Rationale:
Malignant infiltration accounts for 0.5% of acute liver failure cases, with non-Hodgkin's lymphoma the predominant cause. Adult T-cell lymphoma/leukemia (ATLL) is a rarer source of acute hepatitis, with only 3 cases reported and all resulting in immediate deterioration with death. ATLL rises from human T-lymphocytic virus-1 (HTLV-1), commonly found in Japan (southern and northern islands), the Caribbean, Central and South America, intertropical Africa, Romania, and northern Iran. In Micronesia, HTLV-1 infection amongst native-born is absent or exceedingly rare.
Patient Concerns:
A 77-year-old Marshall...
Source: Medicine - July 16, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review
Conclusions
Studies investigating spatially targeted interventions were few in number, and mostly underpowered or otherwise limited methodologically, affecting interpretation of intervention impact. Applying advanced epidemiological methodologies supporting more robust hotspot identification and larger or more intensive interventions would strengthen the evidence-base for this increasingly important approach.
PROSPERO registration number
CRD42019130133. (Source: BMJ Open)
Source: BMJ Open - July 13, 2021 Category: General Medicine Authors: Khundi, M., Carpenter, J. R., Nliwasa, M., Cohen, T., Corbett, E. L., MacPherson, P. Tags: Open access, Public health Source Type: research
Health Beliefs of Diabetic Pacific Islanders in Iowa
AbstractDiabetic Pacific Islanders from the Federated State of Micronesia island state of Pohnpei have settled in rural Iowa. Little is known about the people of Pohnpei. Research was undertaken to examine health practices and cultural beliefs of diabetic Ponapeans. Open-ended questions were utilized to interview 15 adults about their experiences in caring for their diabetes. Four themes were identified among participants: attitude toward diabetes, food choices, barriers to care, and support from community and family. Health care providers must prioritize culturally sensitive care. Understanding the importance of Ponapean ...
Source: Journal of Racial and Ethnic Health Disparities - July 6, 2021 Category: International Medicine & Public Health Source Type: research
Fluorescence Assay for Tolyporphins Amidst Abundant Chlorophyll in Crude Cyanobacterial Extracts
AbstractTolyporphins are distinctive tetrapyrrole natural products found singularly in a filamentous cyanobacterial-microbial holobiont (termed HT-58-2) from Micronesia. The absorption and fluorescence features of tolyporphins resemble those of chlorophylla, complicating direct analysis of culture samples. Treatment of the crude (unfractionated) organic extract (CH2Cl2/2-propanol, 1:1) of HT-58-2 cultures with NaBH4 in methanol causes reduction of the peripheral ketone auxochromes, whereupon tolyporphins (predominantly 7,17-dioxobacteriochlorins) exhibit a bathochromic shift ( λabs ~676 → ~700 nm) and chlorophylla (a 13...
Source: Photochemistry and Photobiology - June 21, 2021 Category: Science Authors: Kathy ‐Uyen Nguyen,
Ran Zhang,
Masahiko Taniguchi,
Jonathan S. Lindsey Tags: RESEARCH ARTICLE Source Type: research
Tolyporphins A –R, unusual tetrapyrrole macrocycles in a cyanobacterium from Micronesia, assessed quantitatively from the culture HT-58-2
New J. Chem., 2021, Advance Article DOI: 10.1039/D1NJ02108G, PaperTimothy J. O'Donnell, Joshua R. Gurr, Jingqiu Dai, Masahiko Taniguchi, Philip G. Williams, Jonathan S. Lindsey Tolyporphins A –R are the newest additions to the family of native tetrapyrroles. LC-MS-dMRM and absorption spectroscopy have been employed for analysis of mixtures containing the 18 distinctive natural products. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - June 8, 2021 Category: Chemistry Authors: Timothy J. O'Donnell Source Type: research
Update on Phytochemical and Biological Studies on Rocaglate Derivatives from Aglaia Species
Planta Med DOI: 10.1055/a-1401-9562With about 120 species, Aglaia is one of the largest genera of the plant family Meliaceae (the mahogany plants). It is native to the tropical rainforests of the Indo-Australian region, ranging from India and Sri Lanka eastward to Polynesia and Micronesia. Various Aglaia species have been investigated since the 1960s for their phytochemical constituents and biological properties, with the cyclopenta[b]benzofurans (rocaglates or flavaglines) being of particular interest. Phytochemists, medicinal chemists, and biologists have conducted extensive research in establishing these secondary metab...
Source: Planta Medica - March 30, 2021 Category: Drugs & Pharmacology Authors: Agarwal, Garima Chang, Long-Sheng Soejarto, Djaja Doel Kinghorn, A. Douglas Tags: Reviews Source Type: research
Molecular Phylogenetics of Hepatitis D Virus in New Zealand and the Implications for Pacific Island Countries
This study supports the probable transmission of HDV Pacific clade around the PI from Micronesia to Polynesi a. The data also confirm the need to screen hepatitis B surface antigen-positive individuals for HDV.Intervirology (Source: Intervirology)
Source: Intervirology - March 1, 2021 Category: Virology Source Type: research
