To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers
Conditions: Sepsis Interventions: Diagnostic Test: flow cytometry; Diagnostic Test: ELISA; Diagnostic Test: RFLP Sponsors: The Republican Research and Practical Center for Epidemiology and Microbiology; Belarusian State Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 21, 2023 Category: Research Source Type: clinical trials

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV
Conditions: Gram Negative Pneumonia; Gram-Negative Bacterial Infections; Bacteremia Caused by Gram-Negative Bacteria Interventions: Drug: Fluorothiazinone, tablets 300 mg at a dose of 2400 mg/day; Other: Placebo Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 16, 2023 Category: Research Source Type: clinical trials

An Open-label Study of the Safety and Pharmacokinetics of the TGKP
Conditions: Acute Respiratory Distress Syndrome (ARDS) Interventions: Drug: Glycolic acid tetrasubstituted piceatannol (TGKP) Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 10, 2023 Category: Research Source Type: clinical trials

Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC: Randomized Clinical Study
Conditions: Quality of Life; Oral Mucositis; Dental Plaque; Periodontal Diseases; Xerostomia; Dysbiosis Interventions: Dietary Supplement: The probiotic to be used in the intervention corresponds to PRODEFEN Plus manufactured by ITALFARMACO S.A. laboratory Sponsors: University of Barcelona Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials

Microbiological Assessment of Bile in Patients Undergone to Endoscopic Retrograde Cholangiography (ERCP): the " Microbile Registry "
Conditions: Jaundice, Obstructive; Jaundice; Malignant; Choledocholithiasis; Biliary Stricture; Biliary Disease Sponsors: Azienda Unit à Sanitaria Locale della Romagna Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 3, 2023 Category: Research Source Type: clinical trials

FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients —efficacy and microbiologic safety
DiscussionThis trial will provide evidence of the efficacy of an alternative drug to ciprofloxacin for febrile neutropenia prevention in high-risk hematological patients. The battery of planned microbiological studies will allow us to evaluate prospectively the microbiological safety of both pharmacological strategies in terms of the selection of MRGNB occurring in each arm. In addition, valuable information on the way in which each drug changes the fecal microbiome of the patients throughout the treatment will be generated.Trial registrationClinical trials NCT05311254, Registered on 5 April 2022,https://clinicaltrials.gov...
Source: Trials - October 27, 2023 Category: Research Source Type: clinical trials

Hydrogen Peroxide Fumigation in Dental Office Environment
Conditions: Bacterial Infections; Dental Caries; Aerosol Disease Interventions: Diagnostic Test: Microbiological analysis after Caries treatment; Diagnostic Test: Microbiological analysis after Caries treatment and fumigation Sponsors: Wroclaw Medical University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 25, 2023 Category: Research Source Type: clinical trials

Evaluation of the Clinical and Microbiological Effects of Chlorhexidine Toothpaste on Wound Healing Following Tooth Extraction
Conditions: Impacted Wisdom Tooth Surgery Interventions: Procedure: Surgery of impacted mandibular wisdom teeth Sponsors: Yuzuncu Y ıl University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

Study of the Vector Vaccine GamCovidVac-M (Altered Antigenic Composition)
Conditions: COVID-19 Interventions: Biological: GamCovidVac-M vector vaccine for the prevention of COVID-19 with altered antigenic composition Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

Study of the Vector Vaccine GamCovidVac for the Prevention of COVID-19 With Altered Antigenic Profile With Participation of Adult Volunteers
Conditions: COVID-19 Interventions: Biological: GamCovidVac vector vaccine for the prevention of COVID-19 (with altered antigenic profile) Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

Clinical and Microbiological Aspects of Probiotics in Non-surgical Periodontal Therapy: a Randomized Controlled Trial.
Conditions: Periodontitis; Probiotics; Non Surgical Periodontal Therapy Interventions: Other: Experimental; Other: Negative control; Other: Positive control Sponsors: G. d ' Annunzio University; Probiotical S.p.A. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 2, 2023 Category: Research Source Type: clinical trials

Clinical and Microbiological Aspects of Probiotics in Non-surgical Periodontal Therapy.
Conditions: Periodontitis; Probiotics; Non Surgical Periodontal Therapy Interventions: Other: Experimental; Other: Negative control; Other: Positive control Sponsors: G. d ' Annunzio University; Probiotical S.p.A. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 2, 2023 Category: Research Source Type: clinical trials

Study of " Sputnik Lite " for the Prevention of COVID-19 With Altered Antigenic Composition.
Condition:   COVID-19 Intervention:   Biological: " Sputnik Lite " vaccine for the prevention of COVID-19 with altered antigenic composition Sponsor:   Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

Study of " Sputnik Lite " for the Prevention of COVID-19 With Altered Antigenic Composition.
Conditions: COVID-19 Interventions: Biological: " Sputnik Lite " vaccine for the prevention of COVID-19 with altered antigenic composition Sponsors: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

Borrelia B-cell Diagnostics
Conditions:   Lyme Disease;   Borrelia Infections Intervention:   Procedure: venous blood puncture Sponsors:   University Children's Hospital, Zurich;   Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials