Carmine Color in Cosmetics – A Natural Colorant?
Carmine is perhaps one of the most interesting pigments used in cosmetics because of its origin and history. If anyone would like a deeper dive into the history, just let me know and I’ll create another post, it’s probably too much to cover here. What is Carmine? Carmine is a bright red pigment based on carminic acid. Carminic acid is derived from the dried bodies of adult female insects and their eggs. Specifically, adult female cochineal (Dactylopius coccus costa) insects. These organisms are almost always sessile and remain on the plants they parasitize, a specific species of cactus (Nopalea coccinelliferna).  On t...
Source: thebeautybrains.com - July 10, 2017 Category: Consumer Health News Authors: Kelly Dobos Tags: Makeup Chemist Raw Materials Science Source Type: blogs

Fluorescing Bandage Senses Wound ’s Healing Process
Bandages used to treat chronic wounds present a host of challenges, particularly when they’re removed to examine and clean a wound. While this is necessary, the process can be very painful for the patient, difficult on the clinician, and the wound may become infected due to being exposed. A team of researchers from Swiss Federal Laboratories for Materials Science and Technology (Empa), ETH Zurich, Centre Suisse d’Electronique et de Microtechnique (CSEM), and University Hospital Zurich set out to create an electronic bandage that can give a glimpse of what’s happening underneath it. This would allow clinical...
Source: Medgadget - July 6, 2017 Category: Medical Devices Authors: Editors Tags: Diagnostics Plastic Surgery Source Type: blogs

Copper ‐Catalyzed Aminothiolation of 1,3‐Dienes via a Dihydrothiazine Intermediate
AngewchemCopper ‐Catalyzed Aminothiolation of 1,3‐Dienes via a Dihydrothiazine Intermediate: Heteroatom ‐containing organic molecules are of particular interest to medicinal chemists and materials scientists. A strategy to reach these architectures via direct difunctionalization of abundant 1,3‐dienes... (Source: Organometallic Current)
Source: Organometallic Current - April 14, 2017 Category: Chemistry Tags: Aminothiolation Cu catalyzed Source Type: blogs

Fiber Optics Integrated Into Fabric Let Clothing Measure Heart Rate
At Empa (Swiss Federal Laboratories for Materials Science and Technology), researchers have developed a way of integrating optic fibers into clothing and using this technology to detect a person’s heart rate. The polymer fibers are highly flexible, keeping the integrated clothing still soft and comfortable. A prototype hat using the new fiber optics was developed so that the tips of the fibers faced toward the skin. By shining light onto the skin and measuring minute changes in the reflected light, the researchers were able to measure people’s heart rate with impressive accuracy. The technology can potentially ...
Source: Medgadget - March 15, 2017 Category: Medical Equipment Authors: Editors Tags: Sports Medicine Source Type: blogs

Polycyclic Aromatic Hydrocarbons via Iron(III)-Catalyzed Carbonyl –Olefin Metathesis - Journal of the American Chemical Society (ACS Publications)
Polycyclic aromatic hydrocarbons are important structural motifs in organic chemistry, pharmaceutical chemistry, and materials science. The development of a new synthetic strategy toward these compounds is described based on the design principle of iron(III)-catalyzed carbonyl –olefin metathesis reactions.  (Source: Organometallic Current)
Source: Organometallic Current - February 22, 2017 Category: Chemistry Tags: Fe catalyzed Metathesis Polycycles Source Type: blogs

One ‐Step Annulative π‐Extension of Alkynes with Dibenzosiloles or Dibenzogermoles by Palladium/o‐chloranil Catalysis
: Reliable and short synthetic routes to polycyclic aromatic hydrocarbons and nanographenes are important in materials science. Herein, we report an efficient one ‐step annulative π‐extension reaction of... (Source: Organometallic Current)
Source: Organometallic Current - December 22, 2016 Category: Chemistry Tags: Pd Catalyzed Polycycles Source Type: blogs

Fight Aging! Newsletter, September 26th 2016
This study included 647 patients 80 to 106 years of age who had audiometric evaluations at an academic medical center (141 had multiple audiograms). The degree of hearing loss was compared across the following age brackets: 80 to 84 years, 85 to 89 years, 90 to 94 years, and 95 years and older. From an individual perspective, the rate of hearing decrease between 2 audiograms was compared with age. The researchers found that changes in hearing among age brackets were higher during the 10th decade of life than the 9th decade at all frequencies for all the patients (average age, 90 years). Correspondingly, the annual rate of ...
Source: Fight Aging! - September 25, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Waking to the Potential of an Age of Biotechnology
I see that the Zuckerbergs have set themselves the ambitious goal of ending disease over the course of this century. Don't forget that these are the spokespeople for an organization, not a few individuals making choices. Billionaires are effectively each the head of their own small state with its own politics and varied goals, the center of circles of delegation and machination, and frequently have less freedom to direct resources than you might think they do. Nonetheless: Chan Zuckerberg Initiative announces $3 billion investment to cure disease The Chan Zuckerberg Initiative just announced a new program i...
Source: Fight Aging! - September 21, 2016 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Finding Adventure: Blake Wiedenheft ’s Path to Gene Editing
Blake Wiedenheft Grew up in: Fort Peck, Montana Fields: Microbiology, biochemistry, structural biology Job site: Montana State University Secret talent: Being a generalist; enjoying many different subjects and activities When not in the lab, he’s: Running, biking, skiing or playing scrabble with his grandmother Scientific discoveries are often stories of adventure. This is the realization that set Blake Wiedenheft on a path toward one of the hottest areas in biology. His story begins in Montana, where he grew up and now lives. Always exploring different interests, Wiedenheft decided in his final semester at Montana Stat...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 11, 2016 Category: Research Authors: Kathryn Calkins Tags: Being a Scientist Genetics Structural Biology Bacteria CRISPR Gene Editing Microbes Profiles Viruses Source Type: blogs

Finding Adventure: Blake Wiedenheft’s Path to Gene Editing
Blake Wiedenheft Grew up in: Fort Peck, Montana Fields: Microbiology, biochemistry, structural biology Job site: Montana State University Secret talent: Being a generalist; enjoying many different subjects and activities When not in the lab, he’s: Running, biking, skiing or playing scrabble with his grandmother Scientific discoveries are often stories of adventure. This is the realization that set Blake Wiedenheft on a path toward one of the hottest areas in biology. His story begins in Montana, where he grew up and now lives. Always exploring different interests, Wiedenheft decided in his final semester at Montana Stat...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 11, 2016 Category: Research Authors: Srivalli Subbaramaiah Tags: Being a Scientist Genetics Structural Biology Bacteria CRISPR Gene Editing Microbes Profiles Viruses Source Type: blogs

Fight Aging! Newsletter, April 11th 2016
In this study we expanded the study by investigating associations of the rest blood parameters with age, and associations between generations, aiming to seek candidate factors associated with familial longevity. Associations of blood parameters in centenarians (CEN) with their first generation of offspring (F1) and F1 spouses (F1SP) were analyzed. In this study, using association and further comparison analyses we identified several blood parameters that may contribute to longevity. First, total cholesterol (TC) and triglyceride (TG) increased with age until 80 years, but decreased in centenarians, indicating that l...
Source: Fight Aging! - April 10, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Researchers Aim for Limb Regeneration by 2030
It is interesting to see more researchers willing to place timelines on the regeneration or tissue engineering of replacement limbs, as is the case here. It is a sign of confidence and progress in the foundations of the field. So far the closest approach to this goal has been the decellularization of donor rat limbs, followed by replacement of cells with those of a potential recipient to produce a leg ready for transplantation, but it seems to me just as likely that human limb regrowth will result from advances in the understanding of regeneration in species like salamanders, in which individuals are capable of regeneratin...
Source: Fight Aging! - November 12, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Dissolving Microneedle Vaccinations
Researchers recently demonstrated that a flu vaccine delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine.The new microneedle patch is made of dissolvable material, eliminating needle-related risks. Not to mention the sea change it may mean for patients with severe needle anxiety!  I suspect this approach may also be more tolerable for many patients than oral and nasal vaccination methods. It is also easy to use without the need for trained medical personnel—making it ideal for use where healthcare resources are limited.“...
Source: The A and P Professor - July 14, 2015 Category: Physiology Authors: Kevin Patton Source Type: blogs

Treating Aging in Advance of Fully Understanding Aging
Engineering is in essence the business of producing good, workable solutions in absence of complete knowledge. The Romans could construct excellent bridges with a tiny fraction of the knowledge of materials science, mathematics, and modeling possessed by today's architects. Medical technologies today are in much the same position: we might know about as much of the fine details of biology as the Romans did of the deeper sciences underlying architecture. A vast scope of discovery and cataloging is yet to be accomplished in the life sciences. Yet we can still produce good therapies well in advance of a full understanding of ...
Source: Fight Aging! - April 30, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Interventions to Slow Aging in Humans: Are We Ready?
The more conservative end of the aging research community is not in favor of engineering approaches like SENS, which focus on repair of the known causes of aging as a way to evade very slow and expensive investigations of the details of how aging progresses, where understanding is still minimal and the unexplored spaces on the map remain very large. Engineering is a matter of doing the best you can in advance of full understanding, and can be highly effective. The Romans built great bridges without modern materials science and architectural understanding, for example. The conservative scientific viewpoint is to require som...
Source: Fight Aging! - April 27, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs