Researcher gets $2.94 million federal grant to study unique features of Ebola and marburg viruses
(Georgia State University) Dr. Christopher Basler, professor and director of the Center for Microbial Pathogenesis in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.94 million federal grant to study unique features of Ebola and Marburg viruses that control how the virus family expresses its genes and escapes immune responses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 15, 2020 Category: Infectious Diseases Source Type: news
New substance library to accelerate the search for active compounds
(Helmholtz-Zentrum Berlin f ü r Materialien und Energie) The MX team at HZB and a Group at the University of Marburg have established a new substance library. It consists of 1103 organic molecules that could be used as building blocks for new drugs. Now, this library has been validated at MAX IV. The substance library of the HZB is available for research worldwide and also plays a role in the search for active substances against SARS-CoV-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2020 Category: International Medicine & Public Health Source Type: news
Cancer drug cures COVID-19 patient with acute respiratory distress
(Philipps-Universit ä t Marburg) A successfully treated case at the Marburg University Medical Center is raising hope for a COVID-19 cure: The team has successfully used the cancer drug ruxolitinib for the first time to cure a patient suffering from acute respiratory distress syndrome (ARDS) after infection with the coronavirus SARS-CoV-2. Oncologist Professor Dr. Andreas Neubauer and his colleagues report on the successfully treated case in the scientific journal Leukemia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 18, 2020 Category: Cancer & Oncology Source Type: news
US inroads to better Ebola vaccine
(Flinders University) As the world focuses on finding a COVID-19 vaccine, research continues on other potentially catastrophic pandemic diseases, including Ebola and Marburg viruses. In the latest collaboration with US partners, a vaccine turbocharger called Advax adjuvant, was combined with a synthetic protein against Ebola developed by the United States Army Medical Research Institute of Infectious Disease (USAMRIID). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2020 Category: International Medicine & Public Health Source Type: news
Researchers uncover mechanisms of protective antibody response during Marburg infection
(University of Texas Medical Branch at Galveston) A detailed study of the monoclonal antibodies from a person who survived a Marburg infection led researchers to identify novel mechanisms that contribute protection against the disease, according to the latest findings of a collaborative team led by The University of Texas Medical Branch at Galveston and Vanderbilt University Medical Center. The findings are now available in Cell Host& Microbe. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 21, 2020 Category: International Medicine & Public Health Source Type: news
Researchers show how Ebola virus hijacks host lipids
(Biophysical Society) Robert Stahelin studies some of the world's deadliest viruses. Filoviruses, including Ebola virus and Marburg virus, cause viral hemorrhagic fever with high fatality rates. Stahelin, professor at Purdue University, examines how these viruses take advantage of human host cells. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 15, 2020 Category: Infectious Diseases Source Type: news
Coronavirus outbreak raises question: Why are bat viruses so deadly?
It's no coincidence that some of the worst viral disease outbreaks in recent years - SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus - originated in bats. A new University of California, Berkeley, study finds that bats' fierce immune response to viruses could drive viruses to replicate faster, so that when they jump to mammals with average immune systems, such as humans, the viruses wreak deadly havoc. (Source: World Pharma News)
Source: World Pharma News - February 10, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Rapid Response Toolbox
Source: Medical Mission Institute. Published: 2/2020.
This toolbox, updated in February 2020, provides information and materials about rapid response to diseases and outbreaks, including situation reports about COVID-19 (coronavirus disease), plague, cholera, Marburg Virus, and Yellow Fever. It provide clinical guidelines, including for COVID-19,chikungunya, dengue, Ebola, and Zika; information about communication and training; and prevention and control information.
(Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 1, 2020 Category: International Medicine & Public Health Source Type: news
How Do Bats Live With So Many Viruses?
They are considered the probable source of the coronavirus outbreak spreading from China. It turns out that they may have an immune system that lets them coexist with many disease-causing viruses. (Source: NYT Health)
Source: NYT Health - January 29, 2020 Category: Consumer Health News Authors: James Gorman Tags: Bats Viruses Epidemics Coronavirus (2019-nCoV) Marburg Virus Nipah Virus Hendra Virus SARS (Severe Acute Respiratory Syndrome) MERS (Middle East Respiratory Syndrome) Immune System Cell Host and Microbe (Journal) EcoHealth Alliance Source Type: news
Marburg virus found in Sierra Leone bats
(University of California - Davis) Scientists have detected Marburg virus in fruit bats in Sierra Leone, marking the first time the deadly virus has been found in West Africa. Eleven Egyptian rousette fruit bats tested positive for active Marburg virus infection. The presence of Marburg virus, a close relative to Ebola virus that also causes hemorrhagic disease in people, was detected in advance of any reported cases of human illness in Sierra Leone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 24, 2020 Category: Infectious Diseases Source Type: news
Ebola and Marburg Fevers: Annual Epidemiological Report for 2018; Surveillance Report
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 12/2019.
This three-page report on cases of Ebola and Marburg fevers is based on data for 2018 retrieved from The European Surveillance System (TESSy) on September 10, 2019. For 2018, no cases of Ebola virus disease and Marburg hemorrhagic fever were reported in the European Union/European Economic Area.
(PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 1, 2019 Category: International Medicine & Public Health Source Type: news
Integral Molecular to advance vaccine discovery with NIH contract for $5.5 million
(Integral Molecular) The NIH has awarded Integral Molecular a contract which will provide up to $5.5M over the next five years to define antibody responses to pathogenic viruses including Zika, Marburg and equine encephalitis viruses (EEV), aiding the discovery of vaccines and therapeutics against these currently untreatable and often lethal viruses. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 14, 2019 Category: Infectious Diseases Source Type: news
Study vaccine protects monkeys against four types of hemorrhagic fever viruses
The vaccine provided protection from Ebola virus, Sudan virus, Marburg virus and Lassa virus. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - November 8, 2019 Category: American Health Source Type: news
Health Emergency Preparedness for Imported Cases of High-Consequence Infectious Diseases: Operational Checklist for Country Preparedness Planning in the EU/EEA Countries; Technical Report
Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 10/22/2019.
To support countries in the European Union/European Economic Area (EU/EEA) in their review of preparedness system planning, this 21-page document provides an operational checklist for health emergency preparedness for imported cases of high-consequence infectious diseases. These diseases include Ebola virus disease, Crimean Congo hemorrhagic fever, Marburg virus disease, highly pathogenic avian influenza, pneumonic plague, and severe acute respiratory syndrome. The checklist describes the system elements that need to ...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 22, 2019 Category: International Medicine & Public Health Source Type: news
Ebola in Zaire, 1976: The Past as Prologue
Source: Centers for Disease Control and Prevention (CDC). Published: 9/5/2019.
This one-hour, 29-minute lecture, part of the Centers for Disease Control and Prevention (CDC) Office of Science “We Were There” series, details how disease detectives discovered the Ebola virus in 1976 in Zaire (now the Democratic Republic of the Congo), and how the understanding of it has grown with subsequent outbreaks over the past 40 years. Samples of the unidentified disease in that outbreak yielded alarming images of a filovirus resembling Marburg, but serology testing at the CDC showed a new virus, later named Ebola.
(Video or Mult...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - September 5, 2019 Category: International Medicine & Public Health Source Type: news
