Fight Aging! Newsletter, October 11th 2021
In conclusion, this study examined how age and the process of aging are associated with changes in the microbiome of the small intestine, using validated sampling and processing techniques. The most significant differences are higher relative abundance of the phylum Proteobacteria and decreased relative abundance of Bacteroidetes in older subjects when compared to the youngest group. The higher relative abundance of Proteobacteria appeared to affect other duodenal microbial taxa, leading to decreased microbial diversity and increased relative abundance of coliforms and of anaerobic bacteria. The small intestine is vital to...
Source: Fight Aging! - October 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
On the Benefits of Estrogens in the Context of Longevity Differences by Gender
Why do women tend to live longer than men? There are a good many possible explanations for this well characterized observation. Gender differences in the pace of aging appears to be a robust outcome of the intersection of natural selection with a given mating strategy, but that doesn't say much about the specific mechanisms involved. Sex hormones are the obvious starting point for any investigation of the relevant molecular biology. In humans, estrogen provides numerous physiological benefits in addition to being a sex hormone, and so a higher estrogen level in women is a possible candidate mechanism.
The tudy repor...
Source: Fight Aging! - October 7, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
EVALI: New information on vaping-induced lung injury
E-cigarettes (vapes) first made headlines due to skyrocketing sales and popularity. Then reports of serious illnesses and deaths related to vaping tobacco and other substances began mounting in summer 2019. By mid-February 2020, the CDC reported more than 2,800 cases of lung injuries requiring hospitalization across all 50 states, and 68 deaths. EVALI, as this illness is now called, continues to generate questions, although emergency department visits related to vaping have been declining.
Why did vaping injuries, and even deaths, seem to occur so suddenly, even though e-cigarettes have been in use for years? Why is EVALI ...
Source: Harvard Health Blog - April 3, 2020 Category: Consumer Health News Authors: Molly Wolf, MD Tags: Addiction Health Lung disease Smoking cessation Source Type: blogs
Fight Aging! Newsletter, October 21st 2019
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - October 20, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Kelsey Moody Presenting on the LysoClear Program at Ending Age-Related Diseases 2019
Kelsey Moody of Ichor Therapeutics presented on the LysoClear development program at the Ending Age-Related Diseases conference organized by the Life Extension Advocacy Foundation earlier this year. LysoClear is an example of the commercial development of a rejuvenation therapy, taken all the way from the starting point of the discovery of microbial enzymes capable of breaking down certain forms of harmful age-related molecular waste that contribute to aging and age-related diseases. The actual research is largely done, and the task now is to focus on manufacture, regulatory approval, and entry into the clinic.
Take...
Source: Fight Aging! - October 14, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Magnetic Nanoclusters For Tumor Destruction
A wide variety of magnetic nanoparticles have been developed by researchers. These devices can be injected into tumors and, using a magnetic field, made to heat up and kill cancer cells. One major challenge with using such nanoparticles is that they are usually expected to be injected using a syringe directly into a tumor, but most tumors aren’t so easy to reach. A more systemic delivery method, which can let magnetic nanoparticles access deep-seated cancers, is very much needed.
Now, researchers at Oregon State University have reported in the journal ACS Nano that they have developed specially designed nanoclust...
Source: Medgadget - June 27, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Medicine Nanomedicine Oncology Source Type: blogs
Pants on Fire
A 37-year-old man presented to the ED with thigh pain. He said his e-cigarette battery exploded in his pants pocket after he placed his keys in the pocket. He said he took his pants off immediately and noted that the battery had melted.His initial vital signs were a temperature of 98.7°F, heart rate of 112 bpm, blood pressure of 159/95 mm Hg, and pulse oximetry of 98% on room air. He had a large area of burns of different degrees on his right thigh. Total body surface area of nine percent with first-, second-, and third-degree burns was noted.E-cigarette use, or vaping, has risen significantly in the past 10 years. The...
Source: The Tox Cave - May 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Why It ’ s Okay to Cry in Public
I waited three months after I was discharged from the hospital for suicidal depression to make contact with the professional world again. I wanted to be sure I didn’t “crack,” like I had done in a group therapy session. A publishing conference seemed like an ideal, safe place to meet. A crowded room of book editors would certainly prevent any emotional outbursts on my part. So I reached out to colleague who had been feeding me assignments pre-nervous breakdown and invited her for a cup of coffee.
“How are you?” she asked me.
I stood there frozen, trying my best to mimic the natural smile I had practiced in front ...
Source: World of Psychology - April 9, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Brain and Behavior Depression General Mental Health and Wellness Self-Help bonding Crying Embarrassment Emotional Expression Source Type: blogs
7 Simple Ways to Ease Anxiety
Anxiety serves a life-saving role when we are in real danger. Adrenaline pumps through our system, and suddenly we can run like Usain Bolt and lift a 200-pound man without much effort. However, most of the time, anxiety is like a fire alarm with a dead battery that beeps annoyingly every five minutes when there is absolutely nothing to worry about. We experience the heart palpitations, restlessness, panic, and nausea as if a saber-toothed tiger were 20 yards away.
Thankfully there are a few simple gestures to communicate to your body that there is no immediate danger — that it’s a false alarm… yet again. I have u...
Source: World of Psychology - April 7, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Anxiety and Panic Mental Health and Wellness Research Self-Help Anxious Thoughts Coping Skills Relaxation Source Type: blogs
New MRI-Based Calcium Sensor Helps Us Better Understand Neuron Activity
Researchers have created a way to use magnetic resonance imaging (MRI) to measure calcium activity in order to analyze signal processing in neuron behavior in living animals, according to a study recently published inNature Communications.Calcium analysis can demonstrate critical neuron activity. However, current technology is limited, and can only enter the first few millimeters of the brain ’s surface. Researchers at the Massachusetts Institute of Technology have developed an MRI-based intracellular calcium sensor that can penetrate cell membranes. The technique identifies magnetic interactions with a manganese-based c...
Source: radRounds - March 16, 2019 Category: Radiology Authors: Julie Morse Source Type: blogs
Does Crying Help or Hurt Depression?
Tears. I liken them to numinous mist or emotional sign language.
“They’re considered a release, a psychological tonic, and to many a glimpse of something deeper: the heart’s own sign language, emotional perspiration from the well of common humanity,” writes Benedict Carey in his New York Times piece “The Muddled Track of All Those Tears.”
The Healing Property of Tears
Tears heal us in several ways. They remove toxins from our body that build up from stress, like the endorphin leucine-enkaphalin and prolactin, the hormone that causes aggression. They lower manganese levels — which triggers anxiety, nervous...
Source: World of Psychology - January 23, 2019 Category: Psychiatry & Psychology Authors: Therese J. Borchard Tags: Depression Grief and Loss Mental Health and Wellness Personal Psychology Self-Help Crying Emotional Expression Source Type: blogs
The Ontario Brain Institute selects 6 neurotech start-ups for ONtrepreneurs program
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Six breakthrough neurotech start-ups win coveted Ontario Brain Institute award (press release):
“Canada’s most prestigious early-stage neurotechnology entrepreneur awards were announced today by the Ontario Brain Institute (OBI). The ONtrepreneurs program, the single largest funder of early-stage neurotech entrepreneurs in Canada, is investing in six early-stage ventures this year to help accelerate their path to commercialization through access to funding, resources, and mentorship … “The ONtrepreneurs program is at the heart of OBI’s mandate to unlock the huge commercial and medical potential from one of th...
Source: SharpBrains - October 5, 2018 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Health & Wellness Technology Cerebian Curv Nanology Labs neurotech Ontario Brain Institute ONtrepreneurs start-ups Supports Health TruReach Welbi Source Type: blogs
Could Baby Teeth Hold the Key to Autism?
A study published in June 2017 found that baby teeth taken from children with autism contain more toxic lead and less of the essential nutrients zinc and manganese compared to teeth from children without autism. Scientists studied twins to control genetic influences and focus on possible environmental contributors to the disease.
The findings suggest that differences in early-life exposure to metals, or more importantly how a child’s body processes them, may affect the risk of autism. These differences were most evident during the months just before and after birth.
This timeline was determined by using lasers to map t...
Source: World of Psychology - June 12, 2018 Category: Psychiatry & Psychology Authors: Janet Singer Tags: Aspergers Autism Children and Teens Research Students Technology Asperger Syndrome Autism Spectrum Disorder autistic Child Development heavy metal exposure lead poisoning manganese Source Type: blogs
Isagenix. – Diet Review
Conclusion – Does Isagenix Work?
Isagenix Isalean’s shake is marketed well, but it’s loaded with sugar and calories. There’s also a lot of protein added, but once you research what kinds of ingredients are included, you realize it’s not a quality meal replacement. The protein added is cheap and can be found for a reduced price elsewhere. Many customers have also complained about the taste, lack of weight loss, and the hard to drink consistency.
There are better options which have only 1 gram of sugar, no added fructose, only high quality whey protein, and great reviews to back up their weight loss claims. T...
Source: Nursing Comments - March 30, 2018 Category: Nursing Authors: M1gu3l Tags: Weight Loss Source Type: blogs
Isagenix. – Diet Review
Conclusion – Does Isagenix Work?
Isagenix Isalean’s shake is marketed well, but it’s loaded with sugar and calories. There’s also a lot of protein added, but once you research what kinds of ingredients are included, you realize it’s not a quality meal replacement. The protein added is cheap and can be found for a reduced price elsewhere. Many customers have also complained about the taste, lack of weight loss, and the hard to drink consistency.
There are better options which have only 1 gram of sugar, no added fructose, only high quality whey protein, and great reviews to back up their weight loss claims. T...
Source: Nursing Comments - March 30, 2018 Category: Nursing Authors: M1gu3l Tags: Weight Loss Source Type: blogs
