Lower limb lymphedema and cellulitis as a complication of COVID ‐19 vaccine: A case report
Physicians should consider secondary lymphedema among the complications of the COVID-19 vaccine. Prolonged inflammation in lymphedema patients might compromise lymphatic function and increase edema. AbstractA 68-year-old man without complications following his first dose of Sinopharm (BBIBP-CorV) COVID-19 vaccine developed left foot and ankle edema, extending to his left leg 3  days after his second dose. Color-Doppler sonography and lymphoscintigraphy showed extensive soft tissue swelling and fat edema in both legs, proposing lymphatic drainage disorder. (Source: Clinical Case Reports)
Source: Clinical Case Reports - December 16, 2022 Category: General Medicine Authors: Ahmad Hosseinzadeh, Kamyar Ebrahimi, Reza Shahriarirad, Farzad Dalfardi Tags: CASE REPORT Source Type: research

Molecules, Vol. 27, Pages 8596: Challenges in Preparation of Albumin Nanoparticle-Based Radiopharmaceuticals
r Albumin nanocolloids have been used as radiopharmaceuticals for more than 40 years. Their main use is in lymphoscintigraphy and the detection of the sentinel lymph node as part of the surgical treatment of a variety of solid tumours. The main licensed products are labelled with the gamma emitter technetium-99m. Recently, two analogues labelled with positron emitters have been reported, using gallium-68 and zirconium-89. For about 10 years, there has been interest in dual-modal agents with both radioactive and fluorescent labels to improve the localisation of the sentinel lymph node. Indocyanine green (ICG) has been t...
Source: Molecules - December 6, 2022 Category: Chemistry Authors: James R. Ballinger Tags: Review Source Type: research

Prognostic Significance and Management of Sentinel Nodes in the Triangular Intermuscular Space of Patients with Melanoma
ConclusionsLymphoscintigraphy showed TIS SNs in 11% of patients with melanomas on their upper back. In such cases, retrieval of TIS SNs is required for accurate staging and to minimize the risk of TIS recurrence. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - December 3, 2022 Category: Cancer & Oncology Source Type: research

Can late lymphoscintigraphy be omitted in the sentinel node procedure in early ‐stage vulvar cancer?
ConclusionsThis study showed good statistical correlations between early and late scintigraphy in most patients. However, in 35% of women late scintigraphy detected more nodes. In case of poor visualization after the first scintigraphy, re-injection should be considered. Late scintigraphy is probably helpful in confirming successful re-injection and in showing deviating lymph flow in women with failed mapping after the first injection and successful re-injection. Because missing metastatic sentinel lymph nodes often leads to a poor prognosis, we prefer optimal correlations between imaging and intraoperative identification....
Source: Acta Obstetricia et Gynecologica Scandinavica - November 22, 2022 Category: OBGYN Authors: Daniek Thissen, Joanne A. Hullu, Marcel J. R. Janssen, Johanna W. M. Aarts Tags: ORIGINAL RESEARCH ARTICLE Source Type: research