Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Systemic Juvenile Idiopathic Arthritis and Secondary Macrophage Activation Syndrome in Latvia from 2009 to 2020: A Nationwide Retrospective Study
Conclusions: The incidence and clinical characteristics of sJIA correlate with the literature findings, although MAS was more common than described in other studies. There is a tendency for the persistent disease to decrease with the use of biological therapy. Tocilizumab is an efficient choice of treatment with a good safety profile.PMID:37109756 | PMC:PMC10144400 | DOI:10.3390/medicina59040798 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2023 Category: Universities & Medical Training Authors: Krist īne Lukjanoviča Ieva Šlēziņa Zane D āvidsone Ruta Šantere Krist īna Budarina Valda Sta ņēviča Source Type: research

Scientists plan a comeback for Ukraine ’s war-ravaged forests
In addition to its horrific human toll, the war in Ukraine has inflicted widespread damage on the nation’s forests. Bombs and missiles have sparked thousands of fires, and “artillery breaks trees in half—it basically mows the forest,” says Brian Milakovsky, a U.S.-born forest ecologist who lived in eastern Ukraine before fleeing the country. Ironically, some forestry experts say the destruction could lead to a major overhaul of how Ukraine manages its forests, changes they say will help ensure these landscapes can better cope with climate change, support biodiversity, and protect water quality. Optimistic tha...
Source: Science of Aging Knowledge Environment - April 19, 2023 Category: Geriatrics Source Type: research

1016 Human leukocyte antigen class II alleles, levels of expression of ORAI1 and STIM1 genes in blood in HIV/TB patients with primary skin pathologies and in a control group in Latvia
This study assessed the distribution of variants of HLA Class II alleles and expression levels of ORAI1 and STIM1 genes in blood between HIV/TB patients with PSP and a control group with no HIV/TB within the Latvian population. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 17, 2023 Category: Dermatology Authors: A. Soha, I. Azina, B. Rozentale, J. Eglite Source Type: research

The impact of government actions and risk perception on the promotion of self-protective behaviors during the COVID-19 pandemic
DiscussionCOVID-19 self-protective behaviors were heterogeneous across countries examined. Our findings show that there is probably no single winning strategy for exiting future health crises, as similar interventions, aimed to promote self-protective behaviors, may be received differently depending on the specific population groups and on the particular geographical context in which they are implemented. (Source: PLoS One)
Source: PLoS One - April 17, 2023 Category: Biomedical Science Authors: Javier Alvarez-Galvez Source Type: research

Marking time: Cosmic ray storms can pin precise dates on history from ancient Egypt to the Vikings
One thousand years ago, according to Viking sagas, intrepid seafarers sailed west from Greenland to a coast they called Vinland. There they set up camps, harvested wild grapes, and skirmished with local people. At an archaeological site in a coastal town in Newfoundland called L’Anse aux Meadows, remnants of structures laid out like Viking longhouses and artifacts such as a bronze cloak pin and iron nails record their presence—likely the first Europeans to set foot in North America. Yet pinning down exactly when Vikings came to Vinland was impossible, until researchers discovered a kind of cosmic timestamp preceding th...
Source: Science of Aging Knowledge Environment - April 13, 2023 Category: Geriatrics Source Type: research