Synergic effects of EP2 and FP receptors co-activation on Blood-Retinal Barrier and Microglia
In this study, we investigated effects of OMD and latanoprost acid (LTA), a FP agonist, on BRB and microglia in vitro and in vivo. To investigate the function of outer/inner BRB and microglia, in vitro, ARPE-19 cells, human retinal microvascular endothelial cells (HRMECs), and MG5 cells were used. Cell viability, inflammatory cytokines mRNA and protein levels, barrier morphology/function, and microglial activation were evaluated using proliferation assays, qRT-PCR, ELISA, immunocytochemistry, trans-epithelial electrical resistance, and permeability assay. Moreover, after vitreous injection into the mouse, outer BRB morphol...
Source: Experimental Eye Research - October 26, 2023 Category: Opthalmology Authors: Natsuko Nakamura Megumi Honjo Reiko Yamagishi Rei Sakata Sumiko Watanabe Makoto Aihara Source Type: research

Synergic effects of EP2 and FP receptors co-activation on Blood-Retinal Barrier and Microglia
In this study, we investigated effects of OMD and latanoprost acid (LTA), a FP agonist, on BRB and microglia in vitro and in vivo. To investigate the function of outer/inner BRB and microglia, in vitro, ARPE-19 cells, human retinal microvascular endothelial cells (HRMECs), and MG5 cells were used. Cell viability, inflammatory cytokines mRNA and protein levels, barrier morphology/function, and microglial activation were evaluated using proliferation assays, qRT-PCR, ELISA, immunocytochemistry, trans-epithelial electrical resistance, and permeability assay. Moreover, after vitreous injection into the mouse, outer BRB morphol...
Source: Experimental Eye Research - October 26, 2023 Category: Opthalmology Authors: Natsuko Nakamura Megumi Honjo Reiko Yamagishi Rei Sakata Sumiko Watanabe Makoto Aihara Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research

Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia
Conclusions: The DNA analysis of the patients with alopecia may contribute to a successful treatment.PMID:37763773 | PMC:PMC10537507 | DOI:10.3390/medicina59091654 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Monica P ăun Gustavo Torres George Sorin Țiplica Victor Mihail Cauni Source Type: research