Zona pellucida removal modifies the expression and release of specific microRNAs in domestic cat blastocysts
In conclusion, in vitro culture of domestic cat embryos without the zona pellucida modifies the expression of miR-21, miR-25, miR-29, miR-199 and miR-96 at the blastocyst stage and the release of miR-21, miR-25 and miR-98.PMID:37724015 | DOI:10.1017/S0967199423000436 (Source: Zygote)
Source: Zygote - September 19, 2023 Category: Reproduction Medicine Authors: Daniel Veraguas-D ávila Diego Caama ño Darling Sa éz-Ruiz Yazm ín Vásquez Fernando Saravia Fidel Ovidio Castro Lleretny Rodr íguez-Alvarez Source Type: research

Zona pellucida removal modifies the expression and release of specific microRNAs in domestic cat blastocysts
In conclusion, in vitro culture of domestic cat embryos without the zona pellucida modifies the expression of miR-21, miR-25, miR-29, miR-199 and miR-96 at the blastocyst stage and the release of miR-21, miR-25 and miR-98.PMID:37724015 | DOI:10.1017/S0967199423000436 (Source: Zygote)
Source: Zygote - September 19, 2023 Category: Reproduction Medicine Authors: Daniel Veraguas-D ávila Diego Caama ño Darling Sa éz-Ruiz Yazm ín Vásquez Fernando Saravia Fidel Ovidio Castro Lleretny Rodr íguez-Alvarez Source Type: research

Zona pellucida removal modifies the expression and release of specific microRNAs in domestic cat blastocysts
In conclusion, in vitro culture of domestic cat embryos without the zona pellucida modifies the expression of miR-21, miR-25, miR-29, miR-199 and miR-96 at the blastocyst stage and the release of miR-21, miR-25 and miR-98.PMID:37724015 | DOI:10.1017/S0967199423000436 (Source: Zygote)
Source: Zygote - September 19, 2023 Category: Reproduction Medicine Authors: Daniel Veraguas-D ávila Diego Caama ño Darling Sa éz-Ruiz Yazm ín Vásquez Fernando Saravia Fidel Ovidio Castro Lleretny Rodr íguez-Alvarez Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research

Kisspeptin decreases the adverse effects of human ovarian vitrification by regulating ROS-related apoptotic occurrences
In this study, the effects of kisspeptin on the improvement of the vitrification and thawing results of human ovarian tissues were investigated. In this work, 12 ovaries from patients who underwent hysterectomy were collected laparoscopically, and then 32 samples from each of their tissues were taken. Haematoxylin and eosin (H&E) staining was performed to check the normality of the ovarian tissue and, subsequently, the samples were allocated randomly into four groups, including: (1) fresh (control), (2) vitrification, (3) vitrified + 1 μM kisspeptin, and (4) vitrified + 10 μM kisspeptin groups. After vitrification, t...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Anahita Tavakoli Fereshteh Aliakbari Malek Soleimani Mehranjani Source Type: research

Obeticholic acid treatment of mice to promote fertilization and reproduction
Zygote. 2023 Sep 1:1-10. doi: 10.1017/S0967199423000400. Online ahead of print.ABSTRACTObeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, has been demonstrated to ameliorate the histopathological characteristics of liver damage. Nonetheless, the systemic safety profile of OCA with regard to reproduction and development remains poorly understood. In the present study, we conducted a dose-response experiment by administering OCA at doses of 5 mg/kg, 10 mg/kg, or 20 mg/kg through tube feeding to investigate its effect on reproductive development and fertilization rate in both male and female mice. Furthermore, we e...
Source: Zygote - September 1, 2023 Category: Reproduction Medicine Authors: Ming Liang Huailiang Yang Lanyong Xu Longqiao Cao Source Type: research