Distinct age ‐adjusted D‐dimer threshold to rule out acute pulmonary embolism in outpatients and inpatients
ConclusionUsing the immunoturbidimetric method to measure DD, an age-adjusted DD cutoff (age  × 10 μg/L, if aged>50  years) should be considered for outpatients with suspected PE. For inpatients, increasing the DD cutoff value to at least 2 × ULN yields the best test performance. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 12, 2024 Category: Respiratory Medicine Authors: Peng Liu, Haixu Yu, Wei Liu, Lin Lin, Ying Qun Ji Tags: ORIGINAL ARTICLE Source Type: research

EGFR amplification indicated poor prognosis in EGFR ‐mutated lung cancer with leptomeningeal metastases
ConclusionEGFR amplification indicated poor prognosis in EGFR-mutated lung cancer with leptomeningeal metastases, providing a novel pathogenesis and treatment direction of these patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 2, 2024 Category: Respiratory Medicine Authors: Di Geng, Ruina Niu, Jinghong Li, Sanxing Guo, Qianqian Guo, Siyuan Huang, Yurong Wang Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 31, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Translation regulatory long non ‐coding RNA 1 negatively regulates cell radiosensitivity via the miR‐22‐3p/SP1 axis in non‐small cell lung cancer
ConclusionTRERNA1 silencing enhanced radiosensitivity of NSCLC cells via the miR-22-3p/SP1 axis. This study may offer new targets for NSCLC treatment. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 30, 2024 Category: Respiratory Medicine Authors: Ming Zhong, Zheng Fang, Weixi Guo, Xiuyi Yu Tags: ORIGINAL ARTICLE Source Type: research

Anti ‐inflammatory effects of reticuline on the JAK2/STAT3/SOCS3 and p38 MAPK/NF‐κB signaling pathway in a mouse model of obesity‐associated asthma
ConclusionReticuline alleviates airway inflammation in obesity-related asthma by inactivating the JAK2/STAT3/SOCS3 and p38 MAPK/NF- κB signaling pathways. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 20, 2024 Category: Respiratory Medicine Authors: Xiaojiang Lyu, Jiaojiao Liu, Zengrong Liu, Ying Wu, Ping Zhu, Chonghai Liu Tags: ORIGINAL ARTICLE Source Type: research

Metformin enhanced the effect of pirfenidone on pulmonary fibrosis in mice
ConclusionMetformin enhanced the antifibrotic effects of pirfenidone on BLM-treated mice. Moreover, these findings provide an experimental basis for examining whether metformin can improve the antifibrotic effects of pirfenidone on patients with idiopathic pulmonary fibrosis (IPF). It has broad therapeutic prospects for patients with IPF. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 18, 2024 Category: Respiratory Medicine Authors: Nana Liu, Yanqiu Song, Ting Liu, Hongyu Wang, Naihao Yu, Hui Ma Tags: ORIGINAL ARTICLE Source Type: research

Construction of brain metastasis prediction model in limited stage small cell lung cancer patients without prophylactic cranial irradiation
ConclusionsA novel nomogram has been developed to forecast the likelihood of BM in patients diagnosed with LS-SCLC. This tool holds the potential to assist healthcare professionals in formulating more informed and tailored treatment plans. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 16, 2024 Category: Respiratory Medicine Authors: Jiayi Guo, Jianjiang Liu, Wanli Ye, Jun Xu, Wangyan Zhong, Xiaoyu Zhang, Hang Yuan, Hao Shi, Ting Li, Yibing Xu, Jiwei Mao, Bin Shen, Dongping Wu Tags: ORIGINAL ARTICLE Source Type: research

Association of biofilm formation, antimicrobial resistance, clinical characteristics, and clinical outcomes among Acinetobacter baumannii isolates from patients with ventilator ‐associated pneumonia
ConclusionBiofilm formation ofA. baumannii causing VAP was associated with antimicrobial resistance and bacteremia as well as unfavorable clinical outcomes. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 12, 2024 Category: Respiratory Medicine Authors: Arnon Chukamnerd, Niwat Saipetch, Kamonnut Singkhamanan, Natnicha Ingviya, Nawaporn Assanangkornchai, Komwit Surachat, Sarunyou Chusri Tags: ORIGINAL ARTICLE Source Type: research

A novel gelatinized barium sulfate injection method for assessment of bronchoalveolar lavage parameters
ConclusionThis novel gelatinized-barium injection technique provides a minimally complex method to yield clinically meaningful feedback on the performance of BAL. The technique is also adaptable to study of procedural parameters in the context of variable lung anatomies and pathologies. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 12, 2024 Category: Respiratory Medicine Authors: Alexander R. Gross, Temitope Kehinde, Lindsey Morais, Marshall Hutchison, Joy Grise, Nada Mohamed, Varun Badami, Haroon Ahmed, Matthew J. Zdilla, Jeffrey A. Vos, Austin G. Gross, Rachel Leonard Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 3, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Down ‐regulation of miR‐21‐5p by pirfenidone to inhibit fibroblast proliferation in the treatment of acquired tracheal stenosis
ConclusionPFD may have a preventive and curative effect on ATS by inhibiting fibroblast proliferation and the fibrotic process and possibly through down-regulating miR-21-5p and up-regulating Smad7 and its mediated fibrotic and inflammatory responses. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 28, 2023 Category: Respiratory Medicine Authors: Wentao Li, Pingping Huang, Jinmei Wei, Sen Tan, Guangnan Liu, Qiu Yang, Guangfa Wang Tags: ORIGINAL ARTICLE Source Type: research

Preoperative pulmonary nodule localization: A comparison of hook wire and Lung ‐pro‐guided surgical markers
ConclusionThe above studies show that the Lung-pro guided surgical marker localization and the CT-guided Hook-wire localization have shown good safety and effectiveness. However, the Lung-pro guided surgical marker localization may show more safety than the Hook-wire and can improve the patient's perioperative experience. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 21, 2023 Category: Respiratory Medicine Authors: Rui He, Chao Ming, Yujie Lei, Wanling Chen, Lianhua Ye, Guangjian Li, Xiangwu Zhang, Boyi Jiang, Teng Zeng, Yunchao Huang, Guangqiang Zhao Tags: ORIGINAL ARTICLE Source Type: research

Acquired tracheomalacia due to SARS ‐CoV‐2 pneumonia
ConclusionsTracheomalacia is an exceptional sequela of SARS-CoV-2 survivors. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 20, 2023 Category: Respiratory Medicine Authors: David Espejo, Marta Zapata, Saliha Omari, Xavier Mu ñoz, Maria‐Jesús Cruz, Se‐COVID‐19 team, Jordi Andreu, Marta Arjona, Cristina Berastegui, Miriam Barrecheguren, José Cardoso, David Clofent, Almudena Felipe, Galo‐David Granados, Tags: LETTER TO THE EDITOR Source Type: research

Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 20, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Determinants of under ‐five pneumonia in randomly selected health facilities at Aleta Wondo Woreda, Sidama Region Ethiopia: Case–control study
ConclusionDeterminants of pneumonia in under-five children were multifactorial (socioeconomic, nutritional, and environmental). Addressing these factors by involving all relevant stakeholders is important to reduce pneumonia-related morbidity and mortality among under-five children in the study area. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 15, 2023 Category: Respiratory Medicine Authors: Tsegaye Alemu, Berihun Ayele, Mende Mensa Sorato Tags: ORIGINAL ARTICLE Source Type: research